ENSG00000034053

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000382938 ENSG00000034053 No_inf pgKDN_inf APBA2 protein_coding retained_intron 4.37731 3.77959 4.63642 0.1746529 0.2522434 0.2940777 0.3934384 0.35663391 0.5516985 0.09241662 0.1482594 0.6154556 0.08778333 0.092100 0.115550 0.023450 0.89868493 0.04446391 FALSE TRUE
ENST00000411764 ENSG00000034053 No_inf pgKDN_inf APBA2 protein_coding protein_coding 4.37731 3.77959 4.63642 0.1746529 0.2522434 0.2940777 1.0256408 1.30577102 0.0000000 0.81589183 0.0000000 -7.0397646 0.24839167 0.350625 0.000000 -0.350625 0.53851213 0.04446391 FALSE TRUE
ENST00000558330 ENSG00000034053 No_inf pgKDN_inf APBA2 protein_coding protein_coding 4.37731 3.77959 4.63642 0.1746529 0.2522434 0.2940777 0.4316470 0.18306198 1.1118791 0.18306198 0.8993299 2.5387812 0.09783333 0.051675 0.241825 0.190150 0.83783269 0.04446391 FALSE TRUE
ENST00000559814 ENSG00000034053 No_inf pgKDN_inf APBA2 protein_coding retained_intron 4.37731 3.77959 4.63642 0.1746529 0.2522434 0.2940777 0.4362852 0.07063814 0.1121803 0.07063814 0.1121803 0.5994777 0.08731667 0.016700 0.022600 0.005900 1.00000000 0.04446391 FALSE TRUE
ENST00000561069 ENSG00000034053 No_inf pgKDN_inf APBA2 protein_coding protein_coding 4.37731 3.77959 4.63642 0.1746529 0.2522434 0.2940777 0.1548469 0.00000000 0.4645407 0.00000000 0.3268965 5.5684600 0.03197500 0.000000 0.095925 0.095925 0.57225247 0.04446391 FALSE TRUE
ENST00000683413 ENSG00000034053 No_inf pgKDN_inf APBA2 protein_coding protein_coding 4.37731 3.77959 4.63642 0.1746529 0.2522434 0.2940777 0.3094299 0.49821301 0.1348280 0.32089029 0.1348280 -1.8110928 0.07571667 0.135325 0.033925 -0.101400 0.80944649 0.04446391 FALSE TRUE
MSTRG.9196.14 ENSG00000034053 No_inf pgKDN_inf APBA2 protein_coding   4.37731 3.77959 4.63642 0.1746529 0.2522434 0.2940777 0.4224091 1.26722718 0.0000000 0.73388557 0.0000000 -6.9968714 0.11011667 0.330350 0.000000 -0.330350 0.49084095 0.04446391 FALSE TRUE
MSTRG.9196.5 ENSG00000034053 No_inf pgKDN_inf APBA2 protein_coding   4.37731 3.77959 4.63642 0.1746529 0.2522434 0.2940777 1.0381895 0.00000000 2.2612932 0.00000000 0.8047927 7.8273702 0.22626667 0.000000 0.490175 0.490175 0.04446391 0.04446391 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000034053 E001 0.0000000       15 28884483 28884613 131 +      
ENSG00000034053 E002 0.0000000       15 28885974 28886021 48 +      
ENSG00000034053 E003 0.3635311 0.0169885461 0.679938139   15 28886022 28886113 92 + 0.163 0.102 -0.785
ENSG00000034053 E004 0.7242644 0.0141818243 0.523566886 0.77675239 15 28886114 28886159 46 + 0.281 0.184 -0.785
ENSG00000034053 E005 0.6056263 0.0159280692 0.780641018 0.91548364 15 28886160 28886162 3 + 0.226 0.184 -0.370
ENSG00000034053 E006 1.4679807 0.0113736801 0.799272684 0.92470661 15 28886163 28886278 116 + 0.374 0.412 0.215
ENSG00000034053 E007 0.0000000       15 28893874 28894044 171 +      
ENSG00000034053 E008 0.1272623 0.0124979948 0.463472403   15 28895520 28895609 90 + 0.000 0.102 10.064
ENSG00000034053 E009 0.0000000       15 28919367 28919487 121 +      
ENSG00000034053 E010 0.1187032 0.0120761091 0.621698709   15 28921637 28921639 3 + 0.089 0.000 -10.704
ENSG00000034053 E011 1.4632294 0.0304132139 0.753510438 0.90304717 15 28921640 28921718 79 + 0.413 0.365 -0.271
ENSG00000034053 E012 0.4830507 0.5036559615 0.653547294   15 28921719 28921749 31 + 0.226 0.102 -1.372
ENSG00000034053 E013 0.0000000       15 28961304 28961584 281 +      
ENSG00000034053 E014 0.0000000       15 28990419 28990796 378 +      
ENSG00000034053 E015 3.1117497 0.0052812831 0.003837647 0.04129369 15 28995753 28995806 54 + 0.761 0.365 -1.856
ENSG00000034053 E016 0.1268540 0.0124073550 0.463612158   15 29028310 29028364 55 + 0.000 0.102 10.064
ENSG00000034053 E017 0.0000000       15 29044324 29044428 105 +      
ENSG00000034053 E018 9.4326709 0.0015970396 0.015997320 0.10965931 15 29053845 29054402 558 + 1.108 0.895 -0.785
ENSG00000034053 E019 8.9315639 0.0017943421 0.767339076 0.90988438 15 29054403 29054835 433 + 0.984 1.010 0.096
ENSG00000034053 E020 0.0000000       15 29070658 29071099 442 +      
ENSG00000034053 E021 3.1513672 0.0053033508 0.227657095 0.51609675 15 29074921 29075001 81 + 0.687 0.528 -0.703
ENSG00000034053 E022 1.5950576 0.0100600613 0.585813215 0.81615575 15 29076055 29076091 37 + 0.374 0.454 0.437
ENSG00000034053 E023 4.2585325 0.0039239527 0.683918143 0.86922521 15 29093075 29093220 146 + 0.744 0.695 -0.200
ENSG00000034053 E024 0.0000000       15 29094278 29094313 36 +      
ENSG00000034053 E025 2.9283434 0.0060133874 0.966736609 0.99332412 15 29098490 29098576 87 + 0.597 0.591 -0.026
ENSG00000034053 E026 6.2385188 0.0024463909 0.687122003 0.87092686 15 29101599 29101784 186 + 0.839 0.880 0.158
ENSG00000034053 E027 2.9253901 0.0062983889 0.969681559 0.99376475 15 29101785 29102759 975 + 0.597 0.591 -0.026
ENSG00000034053 E028 7.1368440 0.0019045703 0.095890754 0.32251010 15 29105379 29105558 180 + 0.825 0.987 0.615
ENSG00000034053 E029 7.7304486 0.0022420653 0.317603712 0.61033416 15 29106607 29106819 213 + 0.893 0.987 0.352
ENSG00000034053 E030 5.4808931 0.0035047005 0.806347965 0.92839149 15 29108270 29108389 120 + 0.825 0.797 -0.107
ENSG00000034053 E031 0.3707119 0.1131950175 0.519715525   15 29108390 29108620 231 + 0.089 0.184 1.215
ENSG00000034053 E032 5.8514146 0.0054930168 0.724350494 0.88928162 15 29113876 29114016 141 + 0.853 0.815 -0.148
ENSG00000034053 E033 20.1249646 0.0008957554 0.053224383 0.22962994 15 29117062 29118315 1254 + 1.267 1.379 0.391

Help

Please Click HERE to learn more details about the results from DEXseq.