ENSG00000038427

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265077 ENSG00000038427 No_inf pgKDN_inf VCAN protein_coding protein_coding 13.94838 27.06409 8.648571 1.648549 0.6950062 -1.644712 0.3668060 0.2133683 0.5833368 0.2133683 0.07193032 1.409427 0.04280833 0.007075 0.067500 0.060425 0.11975515 0.02228713 FALSE TRUE
ENST00000343200 ENSG00000038427 No_inf pgKDN_inf VCAN protein_coding protein_coding 13.94838 27.06409 8.648571 1.648549 0.6950062 -1.644712 0.7120559 0.4102929 1.3717396 0.2370018 0.19251898 1.717019 0.07484167 0.015875 0.158525 0.142650 0.02228713 0.02228713 FALSE TRUE
ENST00000505615 ENSG00000038427 No_inf pgKDN_inf VCAN protein_coding retained_intron 13.94838 27.06409 8.648571 1.648549 0.6950062 -1.644712 7.0886568 14.7045870 4.0837815 0.2646221 0.33610128 -1.845741 0.48240833 0.549725 0.476625 -0.073100 0.83427131 0.02228713 FALSE TRUE
ENST00000507162 ENSG00000038427 No_inf pgKDN_inf VCAN protein_coding protein_coding_CDS_not_defined 13.94838 27.06409 8.648571 1.648549 0.6950062 -1.644712 2.2651528 5.0131265 0.5401546 1.9090573 0.54015462 -3.190677 0.13929167 0.173600 0.050425 -0.123175 0.51893733 0.02228713 TRUE FALSE
MSTRG.23168.11 ENSG00000038427 No_inf pgKDN_inf VCAN protein_coding   13.94838 27.06409 8.648571 1.648549 0.6950062 -1.644712 2.6810906 5.3667346 1.6919760 0.6762658 0.19715617 -1.659520 0.19449167 0.202350 0.202200 -0.000150 1.00000000 0.02228713 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000038427 E001 0.4998907 0.0152721733 1.000000e+00 1.000000000 5 83471618 83471673 56 + 0.145 0.162 0.193
ENSG00000038427 E002 0.4995438 0.0157639889 1.000000e+00   5 83471674 83471743 70 + 0.145 0.162 0.193
ENSG00000038427 E003 0.1265070 0.0123299032 1.000000e+00   5 83471744 83471763 20 + 0.000 0.061 9.104
ENSG00000038427 E004 0.1265070 0.0123299032 1.000000e+00   5 83471764 83471776 13 + 0.000 0.061 9.104
ENSG00000038427 E005 0.1265070 0.0123299032 1.000000e+00   5 83471777 83471790 14 + 0.000 0.061 9.104
ENSG00000038427 E006 0.9966069 0.0205008940 8.718848e-01 0.956088082 5 83471791 83471924 134 + 0.254 0.280 0.193
ENSG00000038427 E007 0.9821553 0.0173007431 1.840264e-01 0.461104705 5 83471925 83472023 99 + 0.413 0.205 -1.392
ENSG00000038427 E008 0.7441847 0.0161905217 7.561144e-01 0.903858215 5 83483513 83483588 76 + 0.254 0.205 -0.392
ENSG00000038427 E009 0.0000000       5 83483589 83483604 16 +      
ENSG00000038427 E010 2.8015598 0.0049504785 3.901695e-03 0.041711404 5 83490098 83490472 375 + 0.789 0.400 -1.771
ENSG00000038427 E011 1.9239083 0.0071677848 9.543756e-05 0.002287915 5 83493546 83493720 175 + 0.760 0.205 -2.977
ENSG00000038427 E012 1.2336612 0.0106907363 4.001270e-01 0.683638162 5 83493804 83493931 128 + 0.413 0.280 -0.807
ENSG00000038427 E013 0.0000000       5 83512102 83512102 1 +      
ENSG00000038427 E014 3.0583177 0.0046079008 1.059220e-02 0.083422265 5 83512103 83512396 294 + 0.789 0.449 -1.508
ENSG00000038427 E015 0.2533610 0.0160122932 8.790605e-01   5 83512397 83512940 544 + 0.000 0.115 10.045
ENSG00000038427 E016 12.8900900 0.0011504537 1.697205e-01 0.441788668 5 83519349 83522309 2961 + 1.173 1.058 -0.413
ENSG00000038427 E017 1.2701700 0.0302952033 2.916332e-02 0.160235350 5 83535614 83536852 1239 + 0.000 0.400 12.096
ENSG00000038427 E018 0.3622142 0.0164498144 1.594930e-01   5 83536853 83537006 154 + 0.254 0.061 -2.392
ENSG00000038427 E019 49.9199181 0.0014493296 1.264464e-03 0.017927480 5 83537007 83539860 2854 + 1.752 1.610 -0.483
ENSG00000038427 E020 64.7237407 0.0002617782 6.324579e-03 0.058630085 5 83539861 83541947 2087 + 1.835 1.734 -0.342
ENSG00000038427 E021 24.8887788 0.0006717425 8.599553e-01 0.951440752 5 83541948 83542268 321 + 1.351 1.363 0.043
ENSG00000038427 E022 0.0000000       5 83544965 83545070 106 +      
ENSG00000038427 E023 13.6090628 0.0011859692 2.710564e-01 0.564729526 5 83545537 83545650 114 + 1.038 1.136 0.356
ENSG00000038427 E024 13.7917348 0.0010319868 1.100498e-02 0.085593407 5 83547971 83548084 114 + 0.931 1.169 0.868
ENSG00000038427 E025 0.0000000       5 83553362 83553363 2 +      
ENSG00000038427 E026 18.3194786 0.0007685406 6.401305e-01 0.847095160 5 83553364 83553522 159 + 1.206 1.242 0.128
ENSG00000038427 E027 11.5561008 0.0019308751 5.824757e-01 0.813971836 5 83554956 83555038 83 + 1.083 1.034 -0.177
ENSG00000038427 E028 14.4665904 0.0010038089 4.015607e-01 0.684679205 5 83572416 83572560 145 + 1.083 1.155 0.260
ENSG00000038427 E029 22.8059100 0.0041990239 5.789298e-01 0.811808793 5 83579980 83580162 183 + 1.293 1.333 0.141
ENSG00000038427 E030 9.3066073 0.0186107403 8.892602e-03 0.074335644 5 83580163 83580306 144 + 0.696 1.028 1.286
ENSG00000038427 E031 137.7056209 0.0001413557 1.118404e-04 0.002608997 5 83580307 83582303 1997 + 2.012 2.110 0.327

Help

Please Click HERE to learn more details about the results from DEXseq.