ENSG00000039123

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000230640 ENSG00000039123 No_inf pgKDN_inf MTREX protein_coding protein_coding 28.7327 24.77252 32.41003 2.14082 1.378771 0.387563 22.672763 14.438062 29.3181247 1.1484670 0.8237528 1.0214088 0.78157500 0.591425 0.909450 0.318025 0.002913677 0.002913677 FALSE TRUE
ENST00000504388 ENSG00000039123 No_inf pgKDN_inf MTREX protein_coding protein_coding_CDS_not_defined 28.7327 24.77252 32.41003 2.14082 1.378771 0.387563 1.612115 1.973881 1.0085763 0.6592666 0.6317494 -0.9617715 0.05555000 0.076425 0.029725 -0.046700 0.556609486 0.002913677 FALSE TRUE
ENST00000518955 ENSG00000039123 No_inf pgKDN_inf MTREX protein_coding retained_intron 28.7327 24.77252 32.41003 2.14082 1.378771 0.387563 2.860704 5.445802 1.2334032 1.9036216 1.2334032 -2.1334969 0.09926667 0.203825 0.034225 -0.169600 0.224347427 0.002913677 FALSE FALSE
MSTRG.22906.8 ENSG00000039123 No_inf pgKDN_inf MTREX protein_coding   28.7327 24.77252 32.41003 2.14082 1.378771 0.387563 0.593542 1.256398 0.3348652 1.2563976 0.1934577 -1.8766260 0.02758333 0.064800 0.010525 -0.054275 0.910957488 0.002913677 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000039123 E001 1.2085813 0.0109718868 0.534687175 0.78461120 5 55307989 55308000 12 + 0.378 0.280 -0.616
ENSG00000039123 E002 1.7988795 0.0075472799 0.108226509 0.34506317 5 55308001 55308009 9 + 0.529 0.280 -1.393
ENSG00000039123 E003 5.6935891 0.0490271758 0.489569576 0.75252068 5 55308010 55308068 59 + 0.854 0.766 -0.348
ENSG00000039123 E004 10.3806149 0.0035097064 0.128015999 0.37917595 5 55308069 55308147 79 + 1.104 0.962 -0.521
ENSG00000039123 E005 21.2258779 0.0155991118 0.057161071 0.23899454 5 55322327 55322464 138 + 1.401 1.238 -0.568
ENSG00000039123 E006 11.2892039 0.0063242140 0.877197327 0.95832617 5 55324132 55324159 28 + 1.090 1.075 -0.056
ENSG00000039123 E007 12.3448113 0.0011160505 0.277278846 0.57065272 5 55324160 55324198 39 + 1.155 1.063 -0.330
ENSG00000039123 E008 0.0000000       5 55324468 55324705 238 +      
ENSG00000039123 E009 0.0000000       5 55327530 55327627 98 +      
ENSG00000039123 E010 0.2539903 0.0159964240 0.128095607   5 55327628 55327715 88 + 0.000 0.205 9.744
ENSG00000039123 E011 8.7367369 0.0015326071 0.722884253 0.88860331 5 55327716 55327778 63 + 0.997 0.962 -0.130
ENSG00000039123 E012 12.2177102 0.0012826542 0.154574569 0.42003349 5 55328699 55328811 113 + 1.161 1.040 -0.437
ENSG00000039123 E013 0.0000000       5 55329356 55329407 52 +      
ENSG00000039123 E014 19.2041600 0.0007319460 0.021957824 0.13448481 5 55340010 55340184 175 + 1.358 1.199 -0.560
ENSG00000039123 E015 14.8147899 0.0047267340 0.685809136 0.87025700 5 55341681 55341771 91 + 1.206 1.173 -0.118
ENSG00000039123 E016 19.8618993 0.0030059901 0.220904435 0.50787586 5 55343331 55343455 125 + 1.347 1.260 -0.302
ENSG00000039123 E017 8.0690955 0.0095619133 0.039573086 0.19290807 5 55344522 55344543 22 + 1.030 0.809 -0.838
ENSG00000039123 E018 11.4455738 0.0012222828 0.024059278 0.14202199 5 55344544 55344585 42 + 1.161 0.962 -0.726
ENSG00000039123 E019 10.6485019 0.0013142638 0.293314885 0.58689093 5 55344586 55344620 35 + 1.097 1.003 -0.345
ENSG00000039123 E020 19.4907213 0.0006676711 0.211690287 0.49672847 5 55345094 55345196 103 + 1.339 1.253 -0.300
ENSG00000039123 E021 22.9651129 0.0010919038 0.050000250 0.22071644 5 55347013 55347144 132 + 1.421 1.295 -0.439
ENSG00000039123 E022 13.6872368 0.0010260822 0.365527080 0.65406393 5 55349573 55349652 80 + 1.190 1.117 -0.261
ENSG00000039123 E023 14.1787356 0.0011483224 0.537333801 0.78636135 5 55350919 55351029 111 + 1.195 1.146 -0.177
ENSG00000039123 E024 16.4346540 0.0009643820 0.648506853 0.85159156 5 55353168 55353269 102 + 1.222 1.253 0.110
ENSG00000039123 E025 23.0325423 0.0005871899 0.280742769 0.57393171 5 55358573 55358698 126 + 1.347 1.411 0.223
ENSG00000039123 E026 30.0617298 0.0004709254 0.407635548 0.69010659 5 55366725 55366875 151 + 1.468 1.511 0.147
ENSG00000039123 E027 31.8557580 0.0004897855 0.200370319 0.48234808 5 55378314 55378486 173 + 1.538 1.468 -0.240
ENSG00000039123 E028 23.3099178 0.0190667255 0.114692975 0.35696526 5 55379127 55379195 69 + 1.431 1.295 -0.472
ENSG00000039123 E029 30.4314811 0.0004738718 0.413262055 0.69406831 5 55387974 55388102 129 + 1.510 1.464 -0.158
ENSG00000039123 E030 23.6456952 0.0014243012 0.456306919 0.72870214 5 55397416 55397526 111 + 1.405 1.357 -0.166
ENSG00000039123 E031 33.4809926 0.0004122288 0.010478165 0.08277858 5 55400233 55400421 189 + 1.474 1.602 0.438
ENSG00000039123 E032 0.4894765 0.0157559404 0.674137073   5 55405252 55405424 173 + 0.145 0.205 0.607
ENSG00000039123 E033 40.3240332 0.0004161596 0.005522895 0.05321040 5 55405425 55405588 164 + 1.553 1.680 0.431
ENSG00000039123 E034 32.9193393 0.0005091400 0.161174627 0.42931610 5 55410524 55410629 106 + 1.493 1.564 0.241
ENSG00000039123 E035 26.8703352 0.0009616869 0.041230382 0.19712077 5 55414182 55414238 57 + 1.388 1.503 0.396
ENSG00000039123 E036 30.4428255 0.0004731247 0.289871234 0.58355101 5 55415970 55416055 86 + 1.468 1.523 0.188
ENSG00000039123 E037 26.4099943 0.0005458986 0.014741111 0.10381915 5 55416056 55416132 77 + 1.369 1.507 0.473
ENSG00000039123 E038 33.0068289 0.0062784064 0.031139337 0.16637716 5 55422878 55422982 105 + 1.468 1.595 0.435
ENSG00000039123 E039 6.5278841 0.0022574567 0.005884071 0.05569524 5 55422983 55424719 1737 + 0.729 1.015 1.101
ENSG00000039123 E040 28.4169048 0.0006592254 0.146790005 0.40784815 5 55424720 55425579 860 + 1.428 1.507 0.271

Help

Please Click HERE to learn more details about the results from DEXseq.