ENSG00000040933

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000409463 ENSG00000040933 No_inf pgKDN_inf INPP4A protein_coding protein_coding 21.06573 45.78462 7.823911 23.15778 0.2053074 -2.547374 0.1978534 0.5935601 0.0000000 0.5935601 0.0000000 -5.9154256 0.01704167 0.051125 0.000000 -0.051125 1.00000000 0.01530454 FALSE TRUE
ENST00000409540 ENSG00000040933 No_inf pgKDN_inf INPP4A protein_coding protein_coding 21.06573 45.78462 7.823911 23.15778 0.2053074 -2.547374 1.8417787 0.4255756 2.1370448 0.2472511 0.1238923 2.3013574 0.20165000 0.023225 0.273475 0.250250 0.01530454 0.01530454 FALSE TRUE
ENST00000409851 ENSG00000040933 No_inf pgKDN_inf INPP4A protein_coding protein_coding 21.06573 45.78462 7.823911 23.15778 0.2053074 -2.547374 5.0810827 6.0111957 4.1098540 0.2643576 0.6126029 -0.5474568 0.46870833 0.342425 0.520675 0.178250 0.67790240 0.01530454 FALSE TRUE
ENST00000468638 ENSG00000040933 No_inf pgKDN_inf INPP4A protein_coding retained_intron 21.06573 45.78462 7.823911 23.15778 0.2053074 -2.547374 1.0508294 1.9253046 0.3399876 0.8683189 0.1990814 -2.4671850 0.06638333 0.069125 0.042025 -0.027100 0.99718882 0.01530454 FALSE FALSE
ENST00000523221 ENSG00000040933 No_inf pgKDN_inf INPP4A protein_coding protein_coding 21.06573 45.78462 7.823911 23.15778 0.2053074 -2.547374 0.2172016 0.0000000 0.6516047 0.0000000 0.6516047 6.0478975 0.02960000 0.000000 0.088800 0.088800 0.68741720 0.01530454 FALSE TRUE
MSTRG.16727.9 ENSG00000040933 No_inf pgKDN_inf INPP4A protein_coding   21.06573 45.78462 7.823911 23.15778 0.2053074 -2.547374 11.8441009 35.5323026 0.0000000 22.6965590 0.0000000 -11.7953214 0.14355000 0.430650 0.000000 -0.430650 0.81405109 0.01530454   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000040933 E001 0.0000000       2 98444854 98444857 4 +      
ENSG00000040933 E002 0.7237664 0.1390367154 2.566474e-01 5.487603e-01 2 98444858 98444949 92 + 0.339 0.148 -1.549
ENSG00000040933 E003 2.7201797 0.0052612703 6.811490e-01 8.682653e-01 2 98444950 98445085 136 + 0.528 0.583 0.257
ENSG00000040933 E004 2.5757057 0.0055147934 5.255341e-01 7.782153e-01 2 98518964 98519025 62 + 0.598 0.509 -0.412
ENSG00000040933 E005 0.6147876 0.1689559905 9.721970e-01 9.947660e-01 2 98519147 98519862 716 + 0.202 0.206 0.036
ENSG00000040933 E006 4.4355848 0.0034854423 9.068295e-01 9.703271e-01 2 98519946 98520048 103 + 0.736 0.720 -0.065
ENSG00000040933 E007 4.8071467 0.0465371380 9.379898e-01 9.821510e-01 2 98520049 98520154 106 + 0.759 0.752 -0.026
ENSG00000040933 E008 3.1876351 0.0193909892 5.950148e-01 8.219485e-01 2 98520687 98520731 45 + 0.658 0.583 -0.327
ENSG00000040933 E009 3.0854803 0.0045921707 9.445254e-01 9.846154e-01 2 98520732 98521766 1035 + 0.598 0.606 0.035
ENSG00000040933 E010 4.9719357 0.0028758777 3.674025e-03 4.005556e-02 2 98533377 98533456 80 + 0.940 0.606 -1.344
ENSG00000040933 E011 4.3533396 0.0090447966 7.584032e-04 1.212681e-02 2 98533457 98533495 39 + 0.925 0.509 -1.735
ENSG00000040933 E012 5.8947929 0.0036886405 1.043926e-06 4.849142e-05 2 98535729 98535845 117 + 1.078 0.535 -2.175
ENSG00000040933 E013 5.3319228 0.1197908007 5.203079e-02 2.264954e-01 2 98536129 98536208 80 + 0.968 0.627 -1.358
ENSG00000040933 E014 6.5748488 0.0030905784 1.455028e-02 1.029186e-01 2 98537863 98537974 112 + 1.008 0.752 -0.981
ENSG00000040933 E015 5.8566655 0.0024346126 6.186341e-02 2.498720e-01 2 98538891 98538981 91 + 0.940 0.736 -0.791
ENSG00000040933 E016 7.4513445 0.0019374845 6.525680e-02 2.571838e-01 2 98539528 98539675 148 + 1.020 0.837 -0.692
ENSG00000040933 E017 6.7371837 0.0021400418 2.112660e-01 4.961646e-01 2 98543877 98544007 131 + 0.954 0.824 -0.498
ENSG00000040933 E018 7.4973672 0.0021014121 5.744794e-01 8.094673e-01 2 98545969 98546073 105 + 0.954 0.896 -0.217
ENSG00000040933 E019 8.4661382 0.0017995712 3.407549e-01 6.323722e-01 2 98546586 98546694 109 + 1.020 0.929 -0.341
ENSG00000040933 E020 0.1271363 0.0123247772 7.898060e-01   2 98548951 98548954 4 + 0.000 0.080 9.300
ENSG00000040933 E021 0.1271363 0.0123247772 7.898060e-01   2 98548955 98548969 15 + 0.000 0.080 9.300
ENSG00000040933 E022 0.7341174 0.0143243953 6.485057e-01 8.515916e-01 2 98550356 98550443 88 + 0.276 0.206 -0.550
ENSG00000040933 E023 10.4265251 0.0014679340 2.357199e-01 5.250489e-01 2 98552786 98552969 184 + 1.109 1.004 -0.380
ENSG00000040933 E024 6.3704382 0.0022278876 1.781168e-01 4.529255e-01 2 98554271 98554424 154 + 0.940 0.797 -0.550
ENSG00000040933 E025 4.8019113 0.0030911931 7.159445e-01 8.854740e-01 2 98554425 98554489 65 + 0.781 0.736 -0.178
ENSG00000040933 E026 8.9796628 0.0016906604 5.866389e-01 8.167846e-01 2 98555553 98555691 139 + 1.020 0.968 -0.192
ENSG00000040933 E027 6.1975807 0.0096794835 3.569860e-01 6.467198e-01 2 98555692 98555808 117 + 0.781 0.885 0.407
ENSG00000040933 E028 2.2486810 0.0429072450 1.272128e-01 3.781676e-01 2 98555809 98556122 314 + 0.339 0.583 1.257
ENSG00000040933 E029 3.4492675 0.0042430329 8.183785e-01 9.339397e-01 2 98559463 98559495 33 + 0.658 0.627 -0.135
ENSG00000040933 E030 11.2851167 0.0012739107 1.668049e-01 4.372202e-01 2 98563465 98563637 173 + 1.147 1.030 -0.424
ENSG00000040933 E031 7.1314278 0.0105874875 5.403343e-01 7.884206e-01 2 98564640 98564763 124 + 0.940 0.874 -0.250
ENSG00000040933 E032 5.9036458 0.0107260074 4.963383e-01 7.573561e-01 2 98565640 98565716 77 + 0.876 0.797 -0.309
ENSG00000040933 E033 6.0106069 0.0089564371 2.641173e-01 5.571816e-01 2 98565717 98565766 50 + 0.909 0.782 -0.491
ENSG00000040933 E034 0.0000000       2 98566028 98566028 1 +      
ENSG00000040933 E035 8.4383393 0.0022770706 5.654400e-02 2.372895e-01 2 98566029 98566169 141 + 1.067 0.885 -0.676
ENSG00000040933 E036 9.0661081 0.0016008842 1.071208e-01 3.430060e-01 2 98568571 98568668 98 + 1.078 0.929 -0.550
ENSG00000040933 E037 0.4897859 0.4662890854 7.639016e-01   2 98568883 98569008 126 + 0.202 0.148 -0.548
ENSG00000040933 E038 1.1225446 0.0110646185 2.455503e-01 5.360877e-01 2 98569158 98569412 255 + 0.202 0.383 1.257
ENSG00000040933 E039 0.5075387 0.0608684949 1.100333e-01 3.481018e-01 2 98569583 98569831 249 + 0.000 0.257 11.054
ENSG00000040933 E040 0.4971544 0.0289012255 5.356976e-01   2 98571897 98572029 133 + 0.113 0.206 1.035
ENSG00000040933 E041 10.2635585 0.0018976699 5.369770e-01 7.861261e-01 2 98572815 98572927 113 + 1.008 1.061 0.196
ENSG00000040933 E042 12.7262525 0.0043010742 7.104495e-01 8.829636e-01 2 98576989 98577143 155 + 1.109 1.138 0.105
ENSG00000040933 E043 1.7388133 0.0105578359 3.544047e-01 6.442137e-01 2 98581576 98581821 246 + 0.339 0.480 0.772
ENSG00000040933 E044 226.4120373 0.0001417243 2.824758e-14 4.534242e-12 2 98587476 98594392 6917 + 2.275 2.385 0.370

Help

Please Click HERE to learn more details about the results from DEXseq.