ENSG00000044115

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000302763 ENSG00000044115 No_inf pgKDN_inf CTNNA1 protein_coding protein_coding 112.1649 84.85136 125.5363 5.822284 4.378259 0.5650402 72.60889 37.175874 86.945709 3.072409 3.089864 1.225526 0.6253917 0.437675 0.695550 0.257875 0.0003267482 0.0003267482 FALSE TRUE
ENST00000520520 ENSG00000044115 No_inf pgKDN_inf CTNNA1 protein_coding protein_coding 112.1649 84.85136 125.5363 5.822284 4.378259 0.5650402 7.31138 15.891857 3.671453 2.286523 3.671453 -2.110848 0.0783500 0.187475 0.028800 -0.158675 0.0062305980 0.0003267482 FALSE TRUE
ENST00000540387 ENSG00000044115 No_inf pgKDN_inf CTNNA1 protein_coding protein_coding 112.1649 84.85136 125.5363 5.822284 4.378259 0.5650402 16.59158 9.391677 21.167931 5.427053 2.396208 1.171572 0.1450500 0.114375 0.168625 0.054250 0.7385702840 0.0003267482 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000044115 E001 0.0000000       5 138610967 138610977 11 +      
ENSG00000044115 E002 0.0000000       5 138610978 138611089 112 +      
ENSG00000044115 E003 0.0000000       5 138653064 138653122 59 +      
ENSG00000044115 E004 0.0000000       5 138663837 138663876 40 +      
ENSG00000044115 E005 0.0000000       5 138723467 138723625 159 +      
ENSG00000044115 E006 0.0000000       5 138753097 138753171 75 +      
ENSG00000044115 E007 0.0000000       5 138753418 138753420 3 +      
ENSG00000044115 E008 0.0000000       5 138753421 138753424 4 +      
ENSG00000044115 E009 0.2372762 0.2501462733 5.574133e-01   5 138753425 138753430 6 + 0.137 0.000 -10.824
ENSG00000044115 E010 2.6939942 0.0052423469 2.072522e-01 4.909496e-01 5 138753431 138753444 14 + 0.482 0.659 0.805
ENSG00000044115 E011 4.1458967 0.0034748223 3.765531e-01 6.637367e-01 5 138753445 138753445 1 + 0.655 0.767 0.464
ENSG00000044115 E012 15.9468697 0.0008390908 2.118182e-01 4.968269e-01 5 138753446 138753510 65 + 1.178 1.274 0.338
ENSG00000044115 E013 0.1187032 0.0118112644 1.000000e+00   5 138753661 138754098 438 + 0.074 0.000 -12.865
ENSG00000044115 E014 0.0000000       5 138754369 138754438 70 +      
ENSG00000044115 E015 0.1176306 0.0117350515 1.000000e+00   5 138754694 138755163 470 + 0.074 0.000 -12.866
ENSG00000044115 E016 0.1265070 0.0122488456 3.017633e-01   5 138761941 138762098 158 + 0.000 0.122 13.004
ENSG00000044115 E017 32.4469595 0.0016623492 3.788019e-01 6.656556e-01 5 138781923 138782029 107 + 1.529 1.483 -0.155
ENSG00000044115 E018 0.0000000       5 138782290 138782403 114 +      
ENSG00000044115 E019 63.9593752 0.0003662136 4.874667e-02 2.175266e-01 5 138783177 138783372 196 + 1.827 1.753 -0.249
ENSG00000044115 E020 0.1170040 0.0116909381 1.000000e+00   5 138783373 138783374 2 + 0.074 0.000 -12.867
ENSG00000044115 E021 0.0000000       5 138790926 138791043 118 +      
ENSG00000044115 E022 80.3381219 0.0010564189 1.188187e-02 8.995460e-02 5 138810038 138810204 167 + 1.930 1.840 -0.301
ENSG00000044115 E023 0.0000000       5 138811959 138812182 224 +      
ENSG00000044115 E024 74.9295305 0.0007085498 3.996166e-02 1.937864e-01 5 138812183 138812302 120 + 1.894 1.822 -0.244
ENSG00000044115 E025 61.8919643 0.0005033112 5.157740e-01 7.716865e-01 5 138824530 138824676 147 + 1.794 1.773 -0.074
ENSG00000044115 E026 48.2700568 0.0050402053 9.704889e-01 9.941189e-01 5 138824677 138824767 91 + 1.678 1.683 0.017
ENSG00000044115 E027 32.1612808 0.0009002742 7.129549e-01 8.840580e-01 5 138824768 138824799 32 + 1.499 1.523 0.082
ENSG00000044115 E028 61.3192758 0.0002487957 1.206416e-01 3.674159e-01 5 138827515 138827626 112 + 1.803 1.746 -0.195
ENSG00000044115 E029 65.6344650 0.0017597181 5.841300e-02 2.420256e-01 5 138827627 138827718 92 + 1.839 1.763 -0.255
ENSG00000044115 E030 0.0000000       5 138827719 138828232 514 +      
ENSG00000044115 E031 0.0000000       5 138870275 138870459 185 +      
ENSG00000044115 E032 0.0000000       5 138874038 138874158 121 +      
ENSG00000044115 E033 0.0000000       5 138875230 138875265 36 +      
ENSG00000044115 E034 0.0000000       5 138875266 138875398 133 +      
ENSG00000044115 E035 0.0000000       5 138875399 138875399 1 +      
ENSG00000044115 E036 0.0000000       5 138875400 138875431 32 +      
ENSG00000044115 E037 0.0000000       5 138875432 138875432 1 +      
ENSG00000044115 E038 0.0000000       5 138875433 138875434 2 +      
ENSG00000044115 E039 0.0000000       5 138875435 138875436 2 +      
ENSG00000044115 E040 0.0000000       5 138875437 138875439 3 +      
ENSG00000044115 E041 0.0000000       5 138875440 138875442 3 +      
ENSG00000044115 E042 0.0000000       5 138875443 138875463 21 +      
ENSG00000044115 E043 0.0000000       5 138875464 138875487 24 +      
ENSG00000044115 E044 0.0000000       5 138875488 138875597 110 +      
ENSG00000044115 E045 0.0000000       5 138875598 138875606 9 +      
ENSG00000044115 E046 0.0000000       5 138875607 138875652 46 +      
ENSG00000044115 E047 0.0000000       5 138875653 138875738 86 +      
ENSG00000044115 E048 0.1272623 0.0123627962 3.016243e-01   5 138880190 138880194 5 + 0.000 0.122 13.002
ENSG00000044115 E049 0.1272623 0.0123627962 3.016243e-01   5 138880195 138880213 19 + 0.000 0.122 13.002
ENSG00000044115 E050 0.2541163 0.0160133602 1.045442e-01   5 138880214 138880288 75 + 0.000 0.217 13.928
ENSG00000044115 E051 0.1268540 0.0122829637 3.017517e-01   5 138880681 138880733 53 + 0.000 0.122 13.003
ENSG00000044115 E052 0.0000000       5 138881042 138881044 3 +      
ENSG00000044115 E053 0.0000000       5 138881045 138881137 93 +      
ENSG00000044115 E054 0.0000000       5 138881138 138881138 1 +      
ENSG00000044115 E055 38.9010195 0.0003660092 4.832265e-02 2.163542e-01 5 138886212 138886228 17 + 1.622 1.527 -0.325
ENSG00000044115 E056 54.0927732 0.0003828769 1.479182e-01 4.094759e-01 5 138886229 138886292 64 + 1.750 1.692 -0.195
ENSG00000044115 E057 89.1421575 0.0004008353 4.804448e-02 2.156640e-01 5 138887490 138887642 153 + 1.965 1.903 -0.210
ENSG00000044115 E058 0.2340080 0.2314109236 5.525484e-01   5 138887643 138887732 90 + 0.137 0.000 -12.708
ENSG00000044115 E059 0.0000000       5 138891183 138891211 29 +      
ENSG00000044115 E060 48.3787706 0.0004955342 1.080613e-01 3.447070e-01 5 138904349 138904398 50 + 1.706 1.637 -0.233
ENSG00000044115 E061 33.7266711 0.0009463410 1.335903e-01 3.883921e-01 5 138904399 138904441 43 + 1.556 1.479 -0.266
ENSG00000044115 E062 0.4991354 0.0152140884 1.240823e-01   5 138904442 138904792 351 + 0.074 0.295 2.390
ENSG00000044115 E063 79.1982995 0.0002089915 2.672294e-01 5.604226e-01 5 138917742 138917898 157 + 1.905 1.870 -0.116
ENSG00000044115 E064 24.0633575 0.0006165640 2.449917e-01 5.353883e-01 5 138924510 138924529 20 + 1.412 1.343 -0.239
ENSG00000044115 E065 47.8743405 0.0003474175 5.807595e-02 2.412242e-01 5 138924530 138924588 59 + 1.706 1.624 -0.278
ENSG00000044115 E066 84.5548715 0.0001782856 6.666036e-02 2.600550e-01 5 138924589 138924710 122 + 1.941 1.883 -0.195
ENSG00000044115 E067 99.2915400 0.0001698613 9.406340e-01 9.831865e-01 5 138925256 138925407 152 + 1.988 1.990 0.006
ENSG00000044115 E068 0.2543986 0.0160573781 1.044405e-01   5 138925408 138925491 84 + 0.000 0.217 13.927
ENSG00000044115 E069 73.4757081 0.0002275500 2.967192e-01 5.899164e-01 5 138929246 138929356 111 + 1.843 1.885 0.140
ENSG00000044115 E070 108.4334181 0.0001873106 2.382322e-01 5.270968e-01 5 138930473 138930637 165 + 2.011 2.050 0.130
ENSG00000044115 E071 42.4166132 0.0007386794 8.070383e-01 9.288123e-01 5 138930638 138930654 17 + 1.628 1.621 -0.025
ENSG00000044115 E072 86.4685796 0.0003025234 8.897403e-01 9.632796e-01 5 138930830 138930935 106 + 1.926 1.935 0.030
ENSG00000044115 E073 2.0902579 0.0138132298 1.831179e-01 4.597896e-01 5 138930936 138931074 139 + 0.395 0.592 0.975
ENSG00000044115 E074 8.1246219 0.0981799608 5.062936e-02 2.224195e-01 5 138931901 138932577 677 + 0.817 1.102 1.066
ENSG00000044115 E075 97.4238058 0.0008279802 2.272823e-01 5.156372e-01 5 138932578 138932712 135 + 1.963 2.007 0.146
ENSG00000044115 E076 1.9954137 0.0206475937 2.606345e-03 3.104475e-02 5 138932888 138932958 71 + 0.241 0.689 2.390
ENSG00000044115 E077 592.0869921 0.0003865490 3.004162e-09 2.361902e-07 5 138933802 138935034 1233 + 2.729 2.807 0.259

Help

Please Click HERE to learn more details about the results from DEXseq.