ENSG00000047249

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355221 ENSG00000047249 No_inf pgKDN_inf ATP6V1H protein_coding protein_coding 85.99321 63.1199 85.97127 2.297095 3.708763 0.445699 1.762590 0.000000 4.745254 0.0000000 1.715526 8.8933785 0.01989167 0.000000 0.054200 0.054200 6.521777e-05 6.521777e-05 FALSE  
ENST00000359530 ENSG00000047249 No_inf pgKDN_inf ATP6V1H protein_coding protein_coding 85.99321 63.1199 85.97127 2.297095 3.708763 0.445699 25.866876 14.326313 28.089539 0.5986413 2.667687 0.9708724 0.29500833 0.228325 0.328400 0.100075 4.097676e-01 6.521777e-05 FALSE  
ENST00000518072 ENSG00000047249 No_inf pgKDN_inf ATP6V1H protein_coding retained_intron 85.99321 63.1199 85.97127 2.297095 3.708763 0.445699 9.620623 3.985584 15.665026 3.9855837 5.543515 1.9719897 0.10600833 0.068350 0.177275 0.108925 3.997893e-01 6.521777e-05    
ENST00000520188 ENSG00000047249 No_inf pgKDN_inf ATP6V1H protein_coding protein_coding 85.99321 63.1199 85.97127 2.297095 3.708763 0.445699 18.085466 10.797673 21.929470 0.7588062 1.933728 1.0214727 0.20870833 0.170600 0.258350 0.087750 4.403536e-01 6.521777e-05 FALSE  
ENST00000523426 ENSG00000047249 No_inf pgKDN_inf ATP6V1H protein_coding protein_coding_CDS_not_defined 85.99321 63.1199 85.97127 2.297095 3.708763 0.445699 17.769841 18.535072 9.130637 3.1278447 3.110802 -1.0206692 0.21003333 0.290050 0.103950 -0.186100 3.890081e-01 6.521777e-05 TRUE  
ENST00000523899 ENSG00000047249 No_inf pgKDN_inf ATP6V1H protein_coding protein_coding_CDS_not_defined 85.99321 63.1199 85.97127 2.297095 3.708763 0.445699 9.519469 12.095778 2.047614 4.1085850 2.047614 -2.5566514 0.11679167 0.187025 0.025300 -0.161725 3.096280e-01 6.521777e-05 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000047249 E001 0.0000000       8 53715543 53715556 14 -      
ENSG00000047249 E002 0.9723400 0.0118794582 0.937356779 0.98208705 8 53715557 53715669 113 - 0.284 0.296 0.082
ENSG00000047249 E003 1.9594689 0.0207278164 0.274112802 0.56763548 8 53715670 53715672 3 - 0.393 0.556 0.819
ENSG00000047249 E004 3.1790652 0.0420156851 0.339541804 0.63119456 8 53715673 53715682 10 - 0.554 0.690 0.597
ENSG00000047249 E005 6.9513311 0.0025683244 0.236400645 0.52543134 8 53715683 53715730 48 - 0.839 0.960 0.463
ENSG00000047249 E006 46.7978503 0.0003523165 0.869613110 0.95513414 8 53715731 53715899 169 - 1.664 1.671 0.022
ENSG00000047249 E007 51.9885478 0.0003496063 0.012371401 0.09213593 8 53715900 53716024 125 - 1.669 1.772 0.349
ENSG00000047249 E008 0.0000000       8 53739553 53739623 71 -      
ENSG00000047249 E009 0.0000000       8 53743517 53743576 60 -      
ENSG00000047249 E010 17.4638540 0.0010491515 0.014774571 0.10393929 8 53743577 53743586 10 - 1.181 1.351 0.597
ENSG00000047249 E011 54.7063535 0.0002795014 0.102928476 0.33538814 8 53743587 53743690 104 - 1.707 1.772 0.221
ENSG00000047249 E012 0.1186381 0.0118564899 1.000000000   8 53743691 53743715 25 - 0.073 0.000 -9.931
ENSG00000047249 E013 0.7351900 0.0537207074 0.505212083 0.76413026 8 53756262 53756554 293 - 0.191 0.296 0.819
ENSG00000047249 E014 62.9799795 0.0002244593 0.484497443 0.74865834 8 53756555 53756656 102 - 1.783 1.809 0.087
ENSG00000047249 E015 43.3799714 0.0003725493 0.003645980 0.03985454 8 53769618 53769653 36 - 1.580 1.711 0.444
ENSG00000047249 E016 48.3798474 0.0003344055 0.088700144 0.30898105 8 53769654 53769743 90 - 1.652 1.724 0.246
ENSG00000047249 E017 76.4505564 0.0023116296 0.759279440 0.90551427 8 53771989 53772167 179 - 1.881 1.868 -0.042
ENSG00000047249 E018 55.4620230 0.0002877862 0.586329374 0.81656357 8 53795647 53795749 103 - 1.747 1.724 -0.078
ENSG00000047249 E019 53.5873167 0.0003076293 0.203770943 0.48640620 8 53795750 53795839 90 - 1.704 1.755 0.174
ENSG00000047249 E020 40.0708378 0.0003609964 0.505748796 0.76457887 8 53801799 53801896 98 - 1.589 1.620 0.106
ENSG00000047249 E021 0.8559352 0.0153716901 0.717897830 0.88650726 8 53806742 53806858 117 - 0.240 0.296 0.404
ENSG00000047249 E022 23.1844322 0.0006385447 0.114901723 0.35730567 8 53811164 53811217 54 - 1.407 1.305 -0.353
ENSG00000047249 E023 16.1590952 0.0035848533 0.098302896 0.32707719 8 53814662 53814674 13 - 1.267 1.136 -0.465
ENSG00000047249 E024 28.0429041 0.0044139874 0.214024998 0.49918212 8 53814675 53814731 57 - 1.479 1.399 -0.275
ENSG00000047249 E025 22.4039634 0.0009312842 0.557095007 0.79922868 8 53814732 53814766 35 - 1.371 1.332 -0.134
ENSG00000047249 E026 37.8018071 0.0003859999 0.039925119 0.19368919 8 53817417 53817530 114 - 1.613 1.508 -0.357
ENSG00000047249 E027 12.8015989 0.0011119124 0.281788477 0.57513641 8 53829444 53829445 2 - 1.160 1.069 -0.326
ENSG00000047249 E028 26.4839687 0.0005646628 0.385650899 0.67157433 8 53829446 53829533 88 - 1.446 1.393 -0.181
ENSG00000047249 E029 1.7308128 0.1423659520 0.086781169 0.30536618 8 53831789 53832864 1076 - 0.284 0.594 1.668
ENSG00000047249 E030 0.2352613 0.2670847862 0.579058051   8 53832865 53832983 119 - 0.136 0.000 -10.930
ENSG00000047249 E031 15.7837124 0.0127677843 0.099869343 0.33017939 8 53832984 53833009 26 - 1.263 1.115 -0.526
ENSG00000047249 E032 21.4018609 0.0046118381 0.002288497 0.02826060 8 53833010 53833060 51 - 1.410 1.185 -0.787
ENSG00000047249 E033 14.6474905 0.0053274858 0.001539681 0.02086521 8 53833061 53833086 26 - 1.267 0.990 -0.996
ENSG00000047249 E034 0.0000000       8 53833087 53833189 103 -      
ENSG00000047249 E035 0.5078243 0.1954438398 0.021755984 0.13390246 8 53839625 53839961 337 - 0.000 0.362 13.464
ENSG00000047249 E036 21.3662343 0.0023378054 0.091452467 0.31404104 8 53841578 53841624 47 - 1.377 1.261 -0.407
ENSG00000047249 E037 26.0281084 0.0005667959 0.599204616 0.82428863 8 53841625 53841725 101 - 1.431 1.399 -0.111
ENSG00000047249 E038 0.2536433 0.0160713383 0.100761705   8 53842504 53842870 367 - 0.000 0.218 12.464
ENSG00000047249 E039 0.1170040 0.0117524424 1.000000000   8 53842871 53842955 85 - 0.073 0.000 -9.931
ENSG00000047249 E040 0.1170040 0.0117524424 1.000000000   8 53842956 53843033 78 - 0.073 0.000 -9.931
ENSG00000047249 E041 28.5452903 0.0008847738 0.262605790 0.55543517 8 53843034 53843558 525 - 1.481 1.416 -0.227

Help

Please Click HERE to learn more details about the results from DEXseq.