ENSG00000047315

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000314595 ENSG00000047315 No_inf pgKDN_inf POLR2B protein_coding protein_coding 76.69624 68.7114 79.26484 2.824803 5.15106 0.2061035 46.02603 29.50344 56.42296 2.324669 1.303960 0.9351659 0.5975750 0.431775 0.721550 0.289775 0.008209626 0.008209626 FALSE TRUE
ENST00000484821 ENSG00000047315 No_inf pgKDN_inf POLR2B protein_coding retained_intron 76.69624 68.7114 79.26484 2.824803 5.15106 0.2061035 23.77567 32.24856 16.98101 2.135524 4.512147 -0.9249106 0.3134583 0.468450 0.205625 -0.262825 0.016530699 0.008209626   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000047315 E001 0.0000000       4 56977722 56977741 20 +      
ENSG00000047315 E002 0.0000000       4 56977742 56977781 40 +      
ENSG00000047315 E003 0.1268540 0.0123304652 3.551518e-01   4 56977782 56977791 10 + 0.000 0.114 10.715
ENSG00000047315 E004 0.0000000       4 56977792 56977808 17 +      
ENSG00000047315 E005 0.0000000       4 56977809 56978000 192 +      
ENSG00000047315 E006 1.6060719 0.0086166409 1.242505e-01 0.3734786404 4 56978640 56978863 224 + 0.301 0.531 1.260
ENSG00000047315 E007 0.3621491 0.0165712649 8.666292e-01   4 56978864 56978868 5 + 0.146 0.114 -0.418
ENSG00000047315 E008 0.9688479 0.0120044841 8.826506e-01 0.9605566116 4 56978869 56978895 27 + 0.301 0.278 -0.155
ENSG00000047315 E009 0.8424059 0.0132459201 5.301872e-01 0.7813644669 4 56978896 56978903 8 + 0.301 0.204 -0.740
ENSG00000047315 E010 17.5368862 0.0008377427 5.822602e-02 0.2415988896 4 56978904 56979004 101 + 1.314 1.178 -0.478
ENSG00000047315 E011 0.3813786 0.0280493600 4.734291e-02   4 56985260 56985279 20 + 0.000 0.278 12.309
ENSG00000047315 E012 1.3490904 0.0356077438 3.532366e-01 0.6430005023 4 56985280 56985457 178 + 0.301 0.447 0.845
ENSG00000047315 E013 23.0026988 0.0005786722 9.700409e-02 0.3244530313 4 56986354 56986426 73 + 1.415 1.311 -0.361
ENSG00000047315 E014 0.0000000       4 56986427 56986803 377 +      
ENSG00000047315 E015 39.2277395 0.0003966762 3.094440e-02 0.1656978687 4 56990748 56990898 151 + 1.640 1.535 -0.358
ENSG00000047315 E016 0.0000000       4 56990899 56990906 8 +      
ENSG00000047315 E017 29.5676196 0.0004705507 1.357325e-03 0.0189573581 4 56994404 56994516 113 + 1.547 1.365 -0.626
ENSG00000047315 E018 40.6045862 0.0054541077 1.797256e-01 0.4549572712 4 56994647 56994866 220 + 1.644 1.567 -0.259
ENSG00000047315 E019 35.0635062 0.0003891218 3.459024e-01 0.6368071071 4 56995251 56995409 159 + 1.571 1.523 -0.163
ENSG00000047315 E020 37.7583021 0.0004171040 1.932078e-02 0.1242174545 4 56999617 56999781 165 + 1.627 1.511 -0.397
ENSG00000047315 E021 49.6145162 0.0083138553 3.608950e-02 0.1823885796 4 57005246 57005442 197 + 1.744 1.627 -0.397
ENSG00000047315 E022 37.4935716 0.0004019188 1.271580e-02 0.0938674086 4 57005600 57005719 120 + 1.627 1.503 -0.425
ENSG00000047315 E023 51.4232406 0.0014374745 2.180134e-01 0.5044330817 4 57006816 57007002 187 + 1.736 1.681 -0.184
ENSG00000047315 E024 2.3214292 0.0062409397 5.256654e-01 0.7783029032 4 57009559 57010172 614 + 0.477 0.568 0.430
ENSG00000047315 E025 0.4896324 0.0158400211 6.906733e-01   4 57010173 57010200 28 + 0.146 0.204 0.582
ENSG00000047315 E026 0.9783833 0.0120946836 5.754096e-01 0.8099102169 4 57010201 57010360 160 + 0.255 0.342 0.582
ENSG00000047315 E027 52.6380358 0.0003809355 1.410740e-01 0.3996367844 4 57010361 57010504 144 + 1.748 1.687 -0.208
ENSG00000047315 E028 50.9825552 0.0002871863 4.033282e-01 0.6863580295 4 57010748 57010887 140 + 1.724 1.689 -0.118
ENSG00000047315 E029 43.2730017 0.0003837538 1.555211e-01 0.4214502358 4 57010989 57011100 112 + 1.667 1.601 -0.222
ENSG00000047315 E030 55.8942068 0.0002501530 8.214382e-01 0.9352046578 4 57015502 57015656 155 + 1.753 1.744 -0.029
ENSG00000047315 E031 0.1170040 0.0117501307 8.136197e-01   4 57015657 57015658 2 + 0.079 0.000 -9.665
ENSG00000047315 E032 74.8552742 0.0002105798 8.111579e-01 0.9305245249 4 57017043 57017241 199 + 1.877 1.870 -0.026
ENSG00000047315 E033 61.7616058 0.0045044535 4.235345e-01 0.7028079557 4 57017560 57017728 169 + 1.775 1.813 0.128
ENSG00000047315 E034 38.1819304 0.0003871839 2.001311e-03 0.0255767601 4 57020899 57020995 97 + 1.519 1.668 0.508
ENSG00000047315 E035 40.2525520 0.0004222397 1.541575e-01 0.4194285329 4 57022152 57022246 95 + 1.580 1.648 0.230
ENSG00000047315 E036 0.2543986 0.0160426500 1.327064e-01   4 57023227 57023329 103 + 0.000 0.204 11.724
ENSG00000047315 E037 64.5402418 0.0002367834 1.714352e-01 0.4439517492 4 57023330 57023490 161 + 1.831 1.780 -0.172
ENSG00000047315 E038 53.5736480 0.0003244562 7.150118e-01 0.8851526895 4 57023491 57023580 90 + 1.737 1.723 -0.049
ENSG00000047315 E039 7.0689089 0.0063278333 3.309908e-05 0.0009380796 4 57023581 57023661 81 + 0.663 1.103 1.698
ENSG00000047315 E040 68.3365093 0.0011751568 1.581126e-01 0.4249374696 4 57023662 57023751 90 + 1.812 1.866 0.184
ENSG00000047315 E041 68.8526510 0.0002381691 9.577639e-03 0.0781719665 4 57024005 57024112 108 + 1.797 1.890 0.315
ENSG00000047315 E042 70.0863313 0.0002045742 6.944316e-05 0.0017436440 4 57024886 57024999 114 + 1.781 1.922 0.476
ENSG00000047315 E043 83.5400466 0.0002095707 9.538865e-04 0.0144595043 4 57025377 57025537 161 + 1.873 1.981 0.362
ENSG00000047315 E044 73.4585739 0.0061995635 2.767050e-01 0.5701383035 4 57030204 57030399 196 + 1.844 1.895 0.173
ENSG00000047315 E045 0.0000000       4 57030899 57031158 260 +      

Help

Please Click HERE to learn more details about the results from DEXseq.