ENSG00000048028

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000003302 ENSG00000048028 No_inf pgKDN_inf USP28 protein_coding protein_coding 3.833154 3.205965 5.154151 0.2045681 0.6620018 0.6832794 0.5535616 0.9202095 0.2849206 0.4545010 0.1737751 -1.657229 0.15314167 0.266425 0.051825 -0.214600 0.54075162 0.03856192 FALSE TRUE
ENST00000542033 ENSG00000048028 No_inf pgKDN_inf USP28 protein_coding protein_coding_CDS_not_defined 3.833154 3.205965 5.154151 0.2045681 0.6620018 0.6832794 0.1028831 0.0000000 0.3086493 0.0000000 0.3086493 4.993898 0.02670000 0.000000 0.080100 0.080100 0.90219011 0.03856192 FALSE TRUE
ENST00000544272 ENSG00000048028 No_inf pgKDN_inf USP28 protein_coding retained_intron 3.833154 3.205965 5.154151 0.2045681 0.6620018 0.6832794 0.4641378 0.0000000 1.3924133 0.0000000 1.0095429 7.131768 0.07858333 0.000000 0.235750 0.235750 0.57948570 0.03856192 FALSE TRUE
ENST00000544750 ENSG00000048028 No_inf pgKDN_inf USP28 protein_coding protein_coding 3.833154 3.205965 5.154151 0.2045681 0.6620018 0.6832794 0.1978165 0.0000000 0.5934496 0.0000000 0.5934496 5.915161 0.03399167 0.000000 0.101975 0.101975 0.88143733 0.03856192   FALSE
ENST00000544967 ENSG00000048028 No_inf pgKDN_inf USP28 protein_coding protein_coding 3.833154 3.205965 5.154151 0.2045681 0.6620018 0.6832794 0.9358456 1.6689333 0.3108989 0.2022755 0.3108989 -2.387354 0.28430833 0.522800 0.072925 -0.449875 0.03856192 0.03856192 FALSE TRUE
MSTRG.5551.3 ENSG00000048028 No_inf pgKDN_inf USP28 protein_coding   3.833154 3.205965 5.154151 0.2045681 0.6620018 0.6832794 1.4647304 0.6168224 2.2638194 0.4203356 0.4812167 1.858989 0.39041667 0.210775 0.457425 0.246650 0.52911698 0.03856192 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000048028 E001 0.0000000       11 113797874 113797874 1 -      
ENSG00000048028 E002 0.2541163 0.016098764 0.268540281   11 113797875 113797908 34 - 0.000 0.168 9.932
ENSG00000048028 E003 2.5926990 0.006078862 0.361355779 0.65081006 11 113797909 113798091 183 - 0.482 0.609 0.596
ENSG00000048028 E004 1.2219531 0.012106736 0.900840195 0.96792704 11 113798092 113798101 10 - 0.356 0.338 -0.105
ENSG00000048028 E005 13.6534684 0.001276110 0.277463544 0.57073679 11 113798102 113798804 703 - 1.120 1.201 0.288
ENSG00000048028 E006 6.8720809 0.010751771 0.792818587 0.92093381 11 113798805 113798978 174 - 0.881 0.907 0.102
ENSG00000048028 E007 5.0227600 0.002936917 0.928556012 0.97886595 11 113798979 113799061 83 - 0.784 0.775 -0.034
ENSG00000048028 E008 10.0349558 0.001510207 0.551069646 0.79502970 11 113799062 113799415 354 - 1.067 1.019 -0.175
ENSG00000048028 E009 3.7958975 0.004093066 0.690755027 0.87301827 11 113801483 113801678 196 - 0.704 0.657 -0.198
ENSG00000048028 E010 0.0000000       11 113801679 113801701 23 -      
ENSG00000048028 E011 3.0601716 0.071526236 0.735945210 0.89521916 11 113803158 113803281 124 - 0.634 0.583 -0.222
ENSG00000048028 E012 2.8180194 0.101415165 0.785162582 0.91717419 11 113803798 113803877 80 - 0.607 0.556 -0.232
ENSG00000048028 E013 2.6801476 0.065651226 0.384441538 0.67059779 11 113804673 113804751 79 - 0.634 0.495 -0.636
ENSG00000048028 E014 1.0809354 0.012577717 0.069807385 0.26722915 11 113804868 113804927 60 - 0.444 0.168 -1.912
ENSG00000048028 E015 2.0703053 0.006694404 0.375906088 0.66312922 11 113804928 113805046 119 - 0.549 0.424 -0.619
ENSG00000048028 E016 0.0000000       11 113806489 113806584 96 -      
ENSG00000048028 E017 0.0000000       11 113807951 113808022 72 -      
ENSG00000048028 E018 0.0000000       11 113808023 113808136 114 -      
ENSG00000048028 E019 4.0353835 0.004659139 0.687276706 0.87096702 11 113808298 113808437 140 - 0.725 0.679 -0.192
ENSG00000048028 E020 4.1679962 0.003935170 0.907228780 0.97053469 11 113809063 113809254 192 - 0.704 0.720 0.065
ENSG00000048028 E021 0.9789530 0.018525486 0.910363866 0.97163368 11 113812276 113812278 3 - 0.304 0.289 -0.105
ENSG00000048028 E022 2.9337058 0.039079199 0.865789475 0.95372968 11 113812279 113812414 136 - 0.607 0.583 -0.105
ENSG00000048028 E023 2.1026855 0.007488914 0.289895984 0.58357905 11 113812415 113812504 90 - 0.402 0.556 0.770
ENSG00000048028 E024 0.0000000       11 113813755 113813839 85 -      
ENSG00000048028 E025 0.0000000       11 113813840 113813884 45 -      
ENSG00000048028 E026 0.7536601 0.013360471 0.111195522 0.35015042 11 113813885 113813955 71 - 0.098 0.338 2.217
ENSG00000048028 E027 1.2371227 0.083013134 0.629166386 0.84097672 11 113815174 113815263 90 - 0.304 0.383 0.480
ENSG00000048028 E028 1.4783666 0.011914461 0.659252101 0.85778637 11 113815264 113815376 113 - 0.356 0.424 0.381
ENSG00000048028 E029 0.7259937 0.016902617 0.362784446 0.65192034 11 113815377 113815382 6 - 0.304 0.168 -1.105
ENSG00000048028 E030 0.9798616 0.011604720 0.911457716 0.97179299 11 113817658 113817694 37 - 0.304 0.289 -0.105
ENSG00000048028 E031 1.1063686 0.010924232 0.830624985 0.93863501 11 113817695 113817705 11 - 0.304 0.338 0.217
ENSG00000048028 E032 2.8065886 0.005547572 0.415193022 0.69532745 11 113817706 113817830 125 - 0.633 0.526 -0.483
ENSG00000048028 E033 0.8705656 0.018493167 0.298568302 0.59160817 11 113817831 113817837 7 - 0.178 0.338 1.217
ENSG00000048028 E034 0.0000000       11 113820292 113820358 67 -      
ENSG00000048028 E035 1.5044266 0.009661071 0.022898183 0.13801862 11 113823605 113823700 96 - 0.178 0.526 2.217
ENSG00000048028 E036 1.8829126 0.055564819 0.007401964 0.06558527 11 113827233 113827360 128 - 0.178 0.609 2.596
ENSG00000048028 E037 0.0000000       11 113828844 113828920 77 -      
ENSG00000048028 E038 0.8787215 0.017433038 0.062003832 0.25012077 11 113829197 113829220 24 - 0.098 0.383 2.480
ENSG00000048028 E039 1.7222897 0.008732864 0.699154789 0.87742494 11 113829221 113829345 125 - 0.402 0.461 0.310
ENSG00000048028 E040 0.0000000       11 113829346 113829467 122 -      
ENSG00000048028 E041 0.8532895 0.013858326 0.631229764 0.84185375 11 113830867 113830882 16 - 0.304 0.233 -0.520
ENSG00000048028 E042 0.9893022 0.012219562 0.550650192 0.79484576 11 113830883 113830943 61 - 0.246 0.338 0.632
ENSG00000048028 E043 0.1271363 0.012543355 0.577253038   11 113830944 113830946 3 - 0.000 0.092 11.619
ENSG00000048028 E044 0.0000000       11 113830947 113830976 30 -      
ENSG00000048028 E045 0.7520260 0.013348022 0.111036523 0.34982440 11 113831920 113831989 70 - 0.098 0.338 2.217
ENSG00000048028 E046 0.3707734 0.016416532 0.631861657   11 113831990 113831993 4 - 0.098 0.168 0.895
ENSG00000048028 E047 1.8447382 0.010433162 0.916597248 0.97377426 11 113833420 113833557 138 - 0.444 0.461 0.088
ENSG00000048028 E048 0.7267188 0.014447089 0.361282361 0.65081006 11 113834249 113834335 87 - 0.304 0.168 -1.105
ENSG00000048028 E049 0.0000000       11 113835207 113835327 121 -      
ENSG00000048028 E050 1.6803936 0.008625437 0.019700229 0.12572620 11 113840598 113840757 160 - 0.579 0.233 -1.979
ENSG00000048028 E051 1.4624080 0.014781907 0.484410590 0.74858029 11 113841663 113841768 106 - 0.444 0.338 -0.590
ENSG00000048028 E052 0.8524383 0.014146405 0.634103873 0.84362609 11 113852501 113852526 26 - 0.304 0.233 -0.520
ENSG00000048028 E053 1.2160069 0.010628890 0.453450293 0.72614799 11 113852527 113852621 95 - 0.402 0.289 -0.690
ENSG00000048028 E054 0.5998373 0.015677716 0.147871522 0.40940979 11 113852622 113852633 12 - 0.304 0.092 -2.105
ENSG00000048028 E055 0.5982032 0.015536621 0.148071780 0.40971065 11 113854258 113854335 78 - 0.304 0.092 -2.105
ENSG00000048028 E056 0.1170040 0.011765899 0.500518335   11 113874517 113874800 284 - 0.098 0.000 -12.483
ENSG00000048028 E057 0.0000000       11 113874801 113874879 79 -      
ENSG00000048028 E058 0.7154869 0.013644968 0.076122754 0.28192511 11 113875445 113875572 128 - 0.356 0.092 -2.427

Help

Please Click HERE to learn more details about the results from DEXseq.