ENSG00000048052

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000405010 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding protein_coding 81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 5.022057 3.768282 11.297889 3.7682821 3.9494981 1.5815273 0.05784167 0.032325 0.141200 0.108875 3.993503e-01 5.091993e-10 FALSE TRUE
ENST00000411993 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding protein_coding_CDS_not_defined 81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 3.364321 9.110346 0.000000 2.3266063 0.0000000 -9.8329448 0.03849167 0.094425 0.000000 -0.094425 5.091993e-10 5.091993e-10   FALSE
ENST00000428307 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding protein_coding 81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 2.445228 4.982028 0.000000 2.8767316 0.0000000 -8.9634821 0.03659167 0.060700 0.000000 -0.060700 5.345315e-01 5.091993e-10 FALSE TRUE
ENST00000471887 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding protein_coding_CDS_not_defined 81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 3.646336 3.995496 3.284827 0.5728119 0.8665653 -0.2817782 0.05445000 0.042850 0.038450 -0.004400 9.131291e-01 5.091993e-10   FALSE
ENST00000622668 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding protein_coding 81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 9.545495 4.134261 15.721595 1.4967404 2.2169415 1.9244783 0.13494167 0.045975 0.168650 0.122675 2.650892e-01 5.091993e-10 FALSE TRUE
MSTRG.25891.1 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding   81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 3.949948 8.697254 2.890500 1.2516439 0.4429410 -1.5859164 0.04462500 0.094125 0.033300 -0.060825 2.274098e-01 5.091993e-10 TRUE FALSE
MSTRG.25891.13 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding   81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 3.279453 1.621591 5.556751 1.2752416 1.4595513 1.7705560 0.05002500 0.014850 0.070775 0.055925 3.361382e-01 5.091993e-10 FALSE TRUE
MSTRG.25891.37 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding   81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 5.926194 9.988733 1.779020 5.7713921 1.7790202 -2.4825756 0.08004167 0.104100 0.012150 -0.091950 8.424444e-01 5.091993e-10 FALSE TRUE
MSTRG.25891.39 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding   81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 4.885367 1.507679 12.663716 1.5076794 1.9899841 3.0619006 0.05793333 0.014000 0.147875 0.133875 1.132115e-02 5.091993e-10 FALSE TRUE
MSTRG.25891.40 ENSG00000048052 No_inf pgKDN_inf HDAC9 protein_coding   81.91768 97.17636 101.1868 8.962491 20.77966 0.0583376 17.812334 12.258196 34.855538 7.0772735 20.8746410 1.5068787 0.15413333 0.109475 0.253200 0.143725 1.000000e+00 5.091993e-10   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000048052 E001 2.1043902 3.327966e-02 3.257235e-01 6.182487e-01 7 18086730 18086948 219 + 0.400 0.558 0.785
ENSG00000048052 E002 11.6414084 3.091025e-03 2.163549e-08 1.444169e-06 7 18086949 18087213 265 + 0.744 1.274 1.969
ENSG00000048052 E003 0.3724075 1.665807e-02 6.337956e-01   7 18087883 18088035 153 + 0.098 0.169 0.911
ENSG00000048052 E004 0.0000000       7 18151775 18151879 105 +      
ENSG00000048052 E005 9.9289467 1.484961e-03 1.924872e-10 1.866468e-08 7 18162229 18162349 121 + 0.577 1.234 2.539
ENSG00000048052 E006 0.3622142 1.664922e-02 5.361274e-01   7 18162350 18162628 279 + 0.178 0.092 -1.089
ENSG00000048052 E007 0.0000000       7 18290092 18290187 96 +      
ENSG00000048052 E008 0.0000000       7 18290188 18290347 160 +      
ENSG00000048052 E009 0.0000000       7 18290348 18290421 74 +      
ENSG00000048052 E010 0.2533610 1.603625e-02 2.704315e-01   7 18290422 18290440 19 + 0.000 0.169 12.852
ENSG00000048052 E011 0.3802150 3.401521e-02 1.217702e-01   7 18290441 18290449 9 + 0.000 0.233 13.332
ENSG00000048052 E012 0.3802150 3.401521e-02 1.217702e-01   7 18290450 18290455 6 + 0.000 0.233 13.332
ENSG00000048052 E013 4.5530933 5.764636e-03 2.926339e-08 1.901556e-06 7 18290456 18290515 60 + 0.178 0.958 3.998
ENSG00000048052 E014 11.2145305 1.714107e-02 8.685997e-11 8.789316e-09 7 18325512 18325592 81 + 0.547 1.296 2.892
ENSG00000048052 E015 43.3088934 7.565767e-03 8.160273e-32 5.177837e-29 7 18327449 18328142 694 + 1.055 1.863 2.796
ENSG00000048052 E016 0.3810317 2.635930e-02 1.209080e-01   7 18395115 18395183 69 + 0.000 0.233 13.362
ENSG00000048052 E017 0.0000000       7 18458842 18458901 60 +      
ENSG00000048052 E018 0.8809875 1.276590e-02 6.252717e-02 2.511676e-01 7 18495669 18495709 41 + 0.098 0.384 2.496
ENSG00000048052 E019 0.7544805 2.837095e-02 1.165907e-01 3.601696e-01 7 18495710 18495714 5 + 0.098 0.340 2.233
ENSG00000048052 E020 0.7547628 1.378406e-01 1.525916e-01 4.166604e-01 7 18495715 18495738 24 + 0.098 0.340 2.233
ENSG00000048052 E021 0.7547628 1.378406e-01 1.525916e-01 4.166604e-01 7 18495739 18495744 6 + 0.098 0.340 2.233
ENSG00000048052 E022 0.6276265 1.695478e-01 2.611274e-01 5.538420e-01 7 18495745 18495745 1 + 0.098 0.290 1.911
ENSG00000048052 E023 0.9819067 7.531730e-02 9.042415e-01 9.691845e-01 7 18495746 18495748 3 + 0.303 0.290 -0.089
ENSG00000048052 E024 1.4627251 9.103340e-03 4.798786e-01 7.454428e-01 7 18495749 18495755 7 + 0.442 0.340 -0.575
ENSG00000048052 E025 1.8238667 7.406179e-03 3.587019e-01 6.481582e-01 7 18495756 18495757 2 + 0.515 0.384 -0.674
ENSG00000048052 E026 3.1680772 4.487249e-03 3.300569e-01 6.225733e-01 7 18495758 18495758 1 + 0.680 0.558 -0.537
ENSG00000048052 E027 3.6373465 3.926491e-03 9.646996e-02 3.235170e-01 7 18495759 18495760 2 + 0.763 0.558 -0.878
ENSG00000048052 E028 9.9200955 1.469712e-03 5.860350e-04 9.880342e-03 7 18495761 18495854 94 + 1.173 0.870 -1.116
ENSG00000048052 E029 9.2527956 1.705678e-03 3.996192e-07 2.025664e-05 7 18495855 18495957 103 + 1.201 0.722 -1.802
ENSG00000048052 E030 7.6252147 1.890209e-03 3.226936e-03 3.647906e-02 7 18495958 18496023 66 + 1.065 0.777 -1.089
ENSG00000048052 E031 0.8893592 1.532526e-02 6.076833e-03 5.701947e-02 7 18496024 18496166 143 + 0.000 0.425 14.537
ENSG00000048052 E032 0.6264628 1.414415e-02 2.013315e-01 4.836582e-01 7 18496167 18496175 9 + 0.098 0.290 1.911
ENSG00000048052 E033 0.7440934 1.324230e-02 4.701033e-01 7.380164e-01 7 18496176 18496261 86 + 0.178 0.290 0.911
ENSG00000048052 E034 9.7163104 1.413647e-03 1.894331e-02 1.225180e-01 7 18496262 18496302 41 + 1.126 0.922 -0.750
ENSG00000048052 E035 10.2419712 1.513748e-03 1.511252e-01 4.142713e-01 7 18496303 18496324 22 + 1.109 0.990 -0.435
ENSG00000048052 E036 0.1176306 1.175186e-02 4.975618e-01   7 18496325 18496496 172 + 0.098 0.000 -12.709
ENSG00000048052 E037 0.1271363 1.234348e-02 5.816740e-01   7 18496497 18496678 182 + 0.000 0.092 11.905
ENSG00000048052 E038 0.0000000       7 18496679 18496746 68 +      
ENSG00000048052 E039 0.4816076 1.533369e-02 2.827635e-01   7 18502353 18502486 134 + 0.245 0.092 -1.674
ENSG00000048052 E040 0.6343313 4.031820e-02 2.769669e-02 1.552477e-01 7 18502581 18502607 27 + 0.000 0.340 13.997
ENSG00000048052 E041 0.8876923 9.883985e-02 1.018625e-02 8.127607e-02 7 18502608 18502639 32 + 0.000 0.425 14.288
ENSG00000048052 E042 0.4986009 3.202584e-02 3.627415e-01   7 18505828 18506036 209 + 0.098 0.233 1.496
ENSG00000048052 E043 0.1268540 1.234323e-02 5.816572e-01   7 18509273 18509311 39 + 0.000 0.092 11.905
ENSG00000048052 E044 0.0000000       7 18509312 18509312 1 +      
ENSG00000048052 E045 0.2537694 1.599736e-02 2.705632e-01   7 18509313 18509331 19 + 0.000 0.169 12.852
ENSG00000048052 E046 3.6329424 9.034342e-02 1.023363e-01 3.343271e-01 7 18509332 18509446 115 + 0.782 0.528 -1.091
ENSG00000048052 E047 4.9487474 2.915130e-03 1.851389e-01 4.626903e-01 7 18517658 18518071 414 + 0.680 0.841 0.648
ENSG00000048052 E048 0.8794769 1.282076e-02 6.248905e-02 2.511676e-01 7 18543169 18543244 76 + 0.098 0.384 2.495
ENSG00000048052 E049 0.6068275 2.024647e-02 5.965659e-01 8.227231e-01 7 18543245 18543285 41 + 0.245 0.169 -0.674
ENSG00000048052 E050 2.0049205 6.111437e-02 2.787804e-02 1.558972e-01 7 18543286 18543674 389 + 0.245 0.611 2.026
ENSG00000048052 E051 1.2225589 6.000199e-02 9.167436e-01 9.738490e-01 7 18544881 18545020 140 + 0.355 0.340 -0.089
ENSG00000048052 E052 10.8516983 3.215832e-03 1.352134e-01 3.908985e-01 7 18585281 18585291 11 + 1.134 1.011 -0.448
ENSG00000048052 E053 38.9575426 3.639129e-04 3.575157e-02 1.813435e-01 7 18585292 18585522 231 + 1.648 1.555 -0.316
ENSG00000048052 E054 7.7420224 1.766694e-03 2.242341e-03 2.787242e-02 7 18590336 18590344 9 + 1.074 0.777 -1.123
ENSG00000048052 E055 32.3908489 9.518242e-03 7.316006e-03 6.505796e-02 7 18590345 18590486 142 + 1.604 1.437 -0.571
ENSG00000048052 E056 36.8324355 6.391392e-03 4.198278e-01 6.992678e-01 7 18591516 18591636 121 + 1.598 1.558 -0.137
ENSG00000048052 E057 14.0590319 7.066176e-03 5.225112e-01 7.759530e-01 7 18591637 18591642 6 + 1.201 1.155 -0.164
ENSG00000048052 E058 33.4652438 1.063090e-03 9.984696e-04 1.499205e-02 7 18593908 18594029 122 + 1.617 1.452 -0.566
ENSG00000048052 E059 19.2969838 5.303733e-03 1.842481e-01 4.614032e-01 7 18629350 18629481 132 + 1.351 1.263 -0.309
ENSG00000048052 E060 29.2511274 6.888461e-04 2.936072e-01 5.871798e-01 7 18634627 18634742 116 + 1.506 1.455 -0.174
ENSG00000048052 E061 33.6024103 1.732744e-03 6.650474e-02 2.598152e-01 7 18644671 18644793 123 + 1.584 1.493 -0.310
ENSG00000048052 E062 50.8449928 2.877018e-04 5.944777e-02 2.446030e-01 7 18647785 18647998 214 + 1.750 1.679 -0.242
ENSG00000048052 E063 58.5436852 2.565682e-04 5.492933e-02 2.334357e-01 7 18648466 18648683 218 + 1.809 1.741 -0.228
ENSG00000048052 E064 2.5483869 5.488885e-03 2.080354e-01 4.917977e-01 7 18654763 18654869 107 + 0.632 0.462 -0.790
ENSG00000048052 E065 0.7287338 1.430210e-01 4.230519e-01 7.022957e-01 7 18656907 18656987 81 + 0.303 0.169 -1.090
ENSG00000048052 E066 0.6247636 1.415078e-02 2.013153e-01 4.836409e-01 7 18657932 18658042 111 + 0.098 0.290 1.911
ENSG00000048052 E067 72.5639021 1.321845e-02 1.496851e-01 4.120743e-01 7 18666213 18666476 264 + 1.907 1.826 -0.274
ENSG00000048052 E068 754.8876818 4.889074e-05 1.355889e-02 9.801439e-02 7 18666477 18669054 2578 + 2.885 2.871 -0.044
ENSG00000048052 E069 0.3709943 1.663585e-02 6.332495e-01   7 18723026 18723087 62 + 0.098 0.169 0.911
ENSG00000048052 E070 3.4368034 2.395262e-02 8.793133e-01 9.592280e-01 7 18727580 18727757 178 + 0.632 0.659 0.117
ENSG00000048052 E071 3.1659489 4.944579e-03 3.314762e-01 6.236400e-01 7 18749005 18749138 134 + 0.680 0.558 -0.537
ENSG00000048052 E072 3.3319735 4.348517e-03 4.527140e-01 7.257459e-01 7 18762157 18762277 121 + 0.577 0.681 0.451
ENSG00000048052 E073 1.8704470 7.246838e-03 9.428705e-02 3.195876e-01 7 18767106 18767155 50 + 0.303 0.558 1.370
ENSG00000048052 E074 0.2459655 1.650583e-02 9.511309e-01   7 18793159 18793344 186 + 0.098 0.092 -0.089
ENSG00000048052 E075 3.3024611 4.407055e-03 6.952679e-01 8.755827e-01 7 18793345 18793452 108 + 0.657 0.611 -0.196
ENSG00000048052 E076 1.8334637 1.456141e-02 6.877037e-01 8.712555e-01 7 18829161 18829216 56 + 0.480 0.425 -0.282
ENSG00000048052 E077 0.6162956 1.880044e-02 7.216109e-01 8.879595e-01 7 18829217 18829392 176 + 0.178 0.233 0.496
ENSG00000048052 E078 3.8169146 4.741014e-03 5.031884e-01 7.627161e-01 7 18829461 18829548 88 + 0.632 0.722 0.380
ENSG00000048052 E079 4.4620749 2.471235e-02 1.066958e-01 3.422262e-01 7 18835467 18835586 120 + 0.605 0.826 0.911
ENSG00000048052 E080 0.0000000       7 18835587 18835649 63 +      
ENSG00000048052 E081 1.7605880 1.444679e-02 8.862680e-03 7.417410e-02 7 18835900 18835908 9 + 0.178 0.585 2.496
ENSG00000048052 E082 3.6017002 3.911051e-03 6.634151e-02 2.594303e-01 7 18835909 18835997 89 + 0.515 0.759 1.063
ENSG00000048052 E083 0.0000000       7 18851400 18851452 53 +      
ENSG00000048052 E084 2.9207018 3.273976e-02 3.548071e-01 6.445107e-01 7 18874478 18874596 119 + 0.657 0.528 -0.575
ENSG00000048052 E085 0.7329261 5.851431e-02 9.282034e-01 9.787238e-01 7 18906938 18907034 97 + 0.245 0.233 -0.089
ENSG00000048052 E086 3.3012944 4.265809e-03 6.953354e-01 8.756268e-01 7 18935809 18935942 134 + 0.657 0.611 -0.196
ENSG00000048052 E087 1.9680027 7.432078e-03 7.346587e-01 8.947292e-01 7 18954146 18954230 85 + 0.442 0.496 0.273
ENSG00000048052 E088 0.0000000       7 18954231 18954316 86 +      
ENSG00000048052 E089 3.9404971 1.283231e-02 6.441884e-01 8.492705e-01 7 18975806 18975953 148 + 0.657 0.722 0.273
ENSG00000048052 E090 246.7689282 8.466666e-04 4.379118e-04 7.864913e-03 7 18996023 19002416 6394 + 2.348 2.429 0.269

Help

Please Click HERE to learn more details about the results from DEXseq.