ENSG00000048740

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354897 ENSG00000048740 No_inf pgKDN_inf CELF2 protein_coding protein_coding 25.17649 21.92602 27.66126 0.1956494 0.2441001 0.3350863 1.1965527 0.000000 2.3994479 0.0000000 1.4071481 7.9125588 0.04379167 0.000000 0.086200 0.086200 0.50780892 0.01988824 FALSE TRUE
ENST00000417956 ENSG00000048740 No_inf pgKDN_inf CELF2 protein_coding protein_coding 25.17649 21.92602 27.66126 0.1956494 0.2441001 0.3350863 0.7185551 0.000000 1.8260852 0.0000000 1.1530230 7.5204892 0.02631667 0.000000 0.065625 0.065625 0.51277629 0.01988824 FALSE TRUE
ENST00000608830 ENSG00000048740 No_inf pgKDN_inf CELF2 protein_coding protein_coding 25.17649 21.92602 27.66126 0.1956494 0.2441001 0.3350863 4.1495501 4.690128 3.6578162 0.7449685 3.6578162 -0.3577787 0.16899167 0.214500 0.130725 -0.083775 0.12220823 0.01988824 FALSE TRUE
ENST00000609870 ENSG00000048740 No_inf pgKDN_inf CELF2 protein_coding nonsense_mediated_decay 25.17649 21.92602 27.66126 0.1956494 0.2441001 0.3350863 1.4115337 0.000000 1.9894791 0.0000000 1.1648631 7.6434804 0.05178333 0.000000 0.072300 0.072300 0.51068185 0.01988824 FALSE TRUE
ENST00000631460 ENSG00000048740 No_inf pgKDN_inf CELF2 protein_coding protein_coding 25.17649 21.92602 27.66126 0.1956494 0.2441001 0.3350863 1.5986273 3.421232 0.0000000 1.2623950 0.0000000 -8.4225828 0.06800000 0.155375 0.000000 -0.155375 0.01988824 0.01988824 FALSE TRUE
MSTRG.3073.15 ENSG00000048740 No_inf pgKDN_inf CELF2 protein_coding   25.17649 21.92602 27.66126 0.1956494 0.2441001 0.3350863 3.8609265 0.000000 5.0521941 0.0000000 2.9226550 8.9836190 0.14507500 0.000000 0.184150 0.184150 0.52032540 0.01988824 FALSE TRUE
MSTRG.3073.16 ENSG00000048740 No_inf pgKDN_inf CELF2 protein_coding   25.17649 21.92602 27.66126 0.1956494 0.2441001 0.3350863 2.1877681 0.000000 5.5043468 0.0000000 2.2368079 9.1070462 0.08123333 0.000000 0.200900 0.200900 0.02305955 0.01988824 FALSE TRUE
MSTRG.3073.17 ENSG00000048740 No_inf pgKDN_inf CELF2 protein_coding   25.17649 21.92602 27.66126 0.1956494 0.2441001 0.3350863 1.7824778 3.189044 0.9557383 1.2476389 0.9557383 -1.7279366 0.07610000 0.145225 0.034475 -0.110750 0.18829292 0.01988824 FALSE TRUE
MSTRG.3073.18 ENSG00000048740 No_inf pgKDN_inf CELF2 protein_coding   25.17649 21.92602 27.66126 0.1956494 0.2441001 0.3350863 5.3289058 7.787342 3.5772359 2.8740877 2.1839734 -1.1201098 0.22274167 0.356825 0.127850 -0.228975 0.64391676 0.01988824 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000048740 E001 0.0000000       10 10798397 10798615 219 +      
ENSG00000048740 E002 0.0000000       10 10798616 10798623 8 +      
ENSG00000048740 E003 0.0000000       10 10798624 10798817 194 +      
ENSG00000048740 E004 0.0000000       10 10846063 10846156 94 +      
ENSG00000048740 E005 0.0000000       10 10919964 10919999 36 +      
ENSG00000048740 E006 0.0000000       10 11005321 11005323 3 +      
ENSG00000048740 E007 0.0000000       10 11005324 11005334 11 +      
ENSG00000048740 E008 0.0000000       10 11005335 11005376 42 +      
ENSG00000048740 E009 0.0000000       10 11005377 11005440 64 +      
ENSG00000048740 E010 0.0000000       10 11017872 11017929 58 +      
ENSG00000048740 E011 0.0000000       10 11017930 11017965 36 +      
ENSG00000048740 E012 0.1170040 1.169052e-02 5.399694e-01   10 11017966 11018163 198 + 0.095 0.000 -9.879
ENSG00000048740 E013 0.0000000       10 11018776 11018864 89 +      
ENSG00000048740 E014 0.0000000       10 11165030 11165058 29 +      
ENSG00000048740 E015 0.3532727 1.575709e-02 1.036065e-01   10 11165059 11165106 48 + 0.239 0.000 -13.182
ENSG00000048740 E016 3.2475645 4.431558e-03 1.194086e-02 9.021718e-02 10 11165107 11165139 33 + 0.770 0.434 -1.513
ENSG00000048740 E017 8.6981201 1.556778e-03 2.249322e-03 2.792702e-02 10 11165140 11165317 178 + 1.113 0.822 -1.089
ENSG00000048740 E018 0.3731018 1.678055e-02 5.815567e-01   10 11165484 11165485 2 + 0.095 0.173 1.002
ENSG00000048740 E019 27.7705656 6.561071e-03 7.101006e-01 8.827808e-01 10 11165486 11165682 197 + 1.472 1.446 -0.087
ENSG00000048740 E020 22.4895688 6.659279e-04 4.772180e-01 7.435584e-01 10 11217425 11217507 83 + 1.393 1.348 -0.155
ENSG00000048740 E021 19.2660706 1.193819e-03 1.637263e-01 4.326512e-01 10 11249153 11249201 49 + 1.353 1.259 -0.328
ENSG00000048740 E022 31.5229358 3.163608e-03 1.949760e-02 1.249653e-01 10 11257738 11257872 135 + 1.576 1.442 -0.459
ENSG00000048740 E023 14.3106758 9.576276e-04 6.178283e-03 5.765044e-02 10 11266598 11266677 80 + 1.281 1.071 -0.748
ENSG00000048740 E024 28.2293736 5.121986e-04 4.074853e-01 6.899822e-01 10 11270666 11270824 159 + 1.489 1.442 -0.161
ENSG00000048740 E025 15.3885829 1.460411e-02 4.727402e-01 7.399591e-01 10 11275057 11275120 64 + 1.246 1.182 -0.228
ENSG00000048740 E026 22.7905657 1.187490e-02 1.116404e-01 3.509683e-01 10 11288418 11288552 135 + 1.434 1.314 -0.418
ENSG00000048740 E027 22.1953594 6.656655e-04 1.089961e-01 3.465947e-01 10 11314139 11314258 120 + 1.414 1.314 -0.349
ENSG00000048740 E028 2.7950458 4.934537e-03 3.051674e-01 5.984686e-01 10 11314259 11314270 12 + 0.646 0.506 -0.635
ENSG00000048740 E029 0.6254549 1.945557e-01 2.357880e-01 5.251483e-01 10 11314271 11314789 519 + 0.095 0.297 2.002
ENSG00000048740 E030 0.0000000       10 11320857 11320898 42 +      
ENSG00000048740 E031 1.2075061 1.018053e-02 2.066544e-01 4.902873e-01 10 11321189 11321206 18 + 0.433 0.239 -1.220
ENSG00000048740 E032 30.9207735 5.091066e-04 4.302083e-01 7.081783e-01 10 11321207 11321386 180 + 1.525 1.483 -0.146
ENSG00000048740 E033 30.8984173 4.607944e-04 2.977864e-01 5.908186e-01 10 11325836 11325979 144 + 1.532 1.476 -0.192
ENSG00000048740 E034 44.9588782 1.608615e-03 9.345374e-01 9.810814e-01 10 11328926 11329097 172 + 1.661 1.663 0.010
ENSG00000048740 E035 101.2306229 1.876255e-04 4.433889e-01 7.182593e-01 10 11329098 11330455 1358 + 1.998 2.020 0.072
ENSG00000048740 E036 722.4031980 6.263537e-05 1.583402e-06 6.943025e-05 10 11330456 11336675 6220 + 2.842 2.875 0.109

Help

Please Click HERE to learn more details about the results from DEXseq.