ENSG00000050130

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000425728 ENSG00000050130 No_inf pgKDN_inf JKAMP protein_coding protein_coding 45.00066 35.15129 50.92837 1.017593 0.8037963 0.5347646 4.118417 1.323474 4.6184375 1.0066176 1.6149424 1.795336 0.08698333 0.035525 0.091400 0.055875 0.70124576 0.0276482 FALSE TRUE
ENST00000553156 ENSG00000050130 No_inf pgKDN_inf JKAMP protein_coding retained_intron 45.00066 35.15129 50.92837 1.017593 0.8037963 0.5347646 2.805022 4.070499 1.9278502 0.7039194 0.7759340 -1.074289 0.06759167 0.116675 0.037350 -0.079325 0.24229132 0.0276482   FALSE
ENST00000553941 ENSG00000050130 No_inf pgKDN_inf JKAMP protein_coding retained_intron 45.00066 35.15129 50.92837 1.017593 0.8037963 0.5347646 1.763320 3.216293 0.5170965 1.9893672 0.3004755 -2.613738 0.04465833 0.092300 0.010375 -0.081925 0.84155977 0.0276482 FALSE TRUE
ENST00000554754 ENSG00000050130 No_inf pgKDN_inf JKAMP protein_coding protein_coding_CDS_not_defined 45.00066 35.15129 50.92837 1.017593 0.8037963 0.5347646 2.773155 6.704666 1.6148007 1.7690976 1.1619335 -2.047053 0.07520000 0.193025 0.032575 -0.160450 0.10113553 0.0276482 TRUE FALSE
ENST00000554795 ENSG00000050130 No_inf pgKDN_inf JKAMP protein_coding protein_coding 45.00066 35.15129 50.92837 1.017593 0.8037963 0.5347646 8.608042 1.374607 11.3476827 1.3746068 2.1638320 3.036120 0.17719167 0.039425 0.222925 0.183500 0.02764820 0.0276482 FALSE FALSE
ENST00000556985 ENSG00000050130 No_inf pgKDN_inf JKAMP protein_coding protein_coding 45.00066 35.15129 50.92837 1.017593 0.8037963 0.5347646 1.953471 2.716943 0.0000000 2.7169426 0.0000000 -8.091141 0.04484167 0.071675 0.000000 -0.071675 0.83428937 0.0276482 FALSE TRUE
ENST00000616435 ENSG00000050130 No_inf pgKDN_inf JKAMP protein_coding protein_coding 45.00066 35.15129 50.92837 1.017593 0.8037963 0.5347646 16.809714 8.127546 25.7766359 1.5768233 3.3970694 1.663958 0.35786667 0.233375 0.504975 0.271600 0.06073666 0.0276482 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000050130 E001 0.0000000       14 59484443 59484444 2 +      
ENSG00000050130 E002 0.5078243 0.1797393678 0.0261199572 0.149454039 14 59484445 59484491 47 + 0.000 0.349 11.563
ENSG00000050130 E003 1.3785160 0.0095114633 0.0036889741 0.040145507 14 59484492 59484502 11 + 0.143 0.577 2.838
ENSG00000050130 E004 1.9871312 0.0073327811 0.0163511098 0.111155693 14 59484503 59484516 14 + 0.295 0.643 1.805
ENSG00000050130 E005 4.9981749 0.0037205466 0.5018071154 0.761585530 14 59484517 59484527 11 + 0.738 0.816 0.314
ENSG00000050130 E006 5.4797215 0.0032201643 0.6322502022 0.842417765 14 59484528 59484530 3 + 0.782 0.836 0.215
ENSG00000050130 E007 5.9602566 0.0025439389 0.7622650598 0.907258548 14 59484531 59484536 6 + 0.822 0.856 0.132
ENSG00000050130 E008 6.9113517 0.0024801132 0.7760623332 0.914037968 14 59484537 59484544 8 + 0.903 0.874 -0.110
ENSG00000050130 E009 8.3913594 0.0045510693 0.7556013506 0.903665504 14 59484545 59484559 15 + 0.952 0.984 0.118
ENSG00000050130 E010 9.4427760 0.0085501717 0.4832607240 0.747917699 14 59484560 59484568 9 + 1.038 0.970 -0.249
ENSG00000050130 E011 11.3565898 0.0032969607 0.1818770708 0.457931840 14 59484569 59484593 25 + 1.128 1.011 -0.425
ENSG00000050130 E012 5.4154453 0.0088379229 0.0193972059 0.124499453 14 59484594 59484989 396 + 0.671 0.940 1.064
ENSG00000050130 E013 2.9567711 0.1520187242 0.2221457440 0.509470109 14 59484990 59485116 127 + 0.469 0.726 1.152
ENSG00000050130 E014 3.3540085 0.0059959892 0.0010375751 0.015416137 14 59485465 59485968 504 + 0.407 0.836 1.916
ENSG00000050130 E015 1.4677899 0.1094415994 0.5193532833 0.774089637 14 59486681 59486712 32 + 0.335 0.455 0.668
ENSG00000050130 E016 10.0468082 0.0028734125 0.4886375254 0.751916300 14 59486713 59486730 18 + 1.060 0.998 -0.229
ENSG00000050130 E017 20.2634127 0.0125466346 0.9578081836 0.989905942 14 59486731 59486804 74 + 1.322 1.317 -0.018
ENSG00000050130 E018 5.3300700 0.0026202794 0.0001565449 0.003412729 14 59487194 59487673 480 + 0.570 0.998 1.719
ENSG00000050130 E019 46.0110903 0.0003790852 0.2397721029 0.528824266 14 59487674 59487828 155 + 1.643 1.694 0.175
ENSG00000050130 E020 27.0797299 0.0006188198 0.9710286455 0.994322655 14 59495018 59495087 70 + 1.441 1.440 -0.004
ENSG00000050130 E021 38.1095309 0.0004104250 0.8610951794 0.951853949 14 59495088 59495224 137 + 1.587 1.580 -0.025
ENSG00000050130 E022 0.0000000       14 59495225 59495305 81 +      
ENSG00000050130 E023 49.4392515 0.0003433508 0.2081189488 0.491853642 14 59498727 59498908 182 + 1.715 1.663 -0.176
ENSG00000050130 E024 1.8401427 0.0077051990 0.2570817203 0.549387650 14 59500882 59501190 309 + 0.373 0.540 0.861
ENSG00000050130 E025 32.7152418 0.0013326886 0.0025052184 0.030153191 14 59501191 59501267 77 + 1.579 1.415 -0.562
ENSG00000050130 E026 163.2432653 0.0020100408 0.4013010919 0.684517020 14 59503854 59505410 1557 + 2.215 2.196 -0.062

Help

Please Click HERE to learn more details about the results from DEXseq.