ENSG00000050748

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000347470 ENSG00000050748 No_inf pgKDN_inf MAPK9 protein_coding protein_coding 21.06517 19.1216 22.29827 0.7399486 0.2506317 0.2216206 5.232350 1.241752 7.362783 1.2417518 0.6885111 2.5582607 0.2386500 0.059825 0.329600 0.269775 2.809209e-02 2.346277e-10 FALSE TRUE
ENST00000393360 ENSG00000050748 No_inf pgKDN_inf MAPK9 protein_coding protein_coding 21.06517 19.1216 22.29827 0.7399486 0.2506317 0.2216206 4.178977 3.574013 4.805186 0.9003970 0.3034327 0.4260156 0.1983750 0.188950 0.215875 0.026925 8.867952e-01 2.346277e-10 FALSE TRUE
ENST00000397072 ENSG00000050748 No_inf pgKDN_inf MAPK9 protein_coding protein_coding 21.06517 19.1216 22.29827 0.7399486 0.2506317 0.2216206 2.400521 2.299250 2.576665 0.4586776 0.8771413 0.1636689 0.1137667 0.120775 0.116150 -0.004625 9.543695e-01 2.346277e-10 FALSE TRUE
ENST00000425491 ENSG00000050748 No_inf pgKDN_inf MAPK9 protein_coding protein_coding 21.06517 19.1216 22.29827 0.7399486 0.2506317 0.2216206 1.389637 1.578873 1.420980 0.1968074 0.2047904 -0.1510003 0.0669000 0.083875 0.063825 -0.020050 8.733662e-01 2.346277e-10 FALSE TRUE
MSTRG.24039.5 ENSG00000050748 No_inf pgKDN_inf MAPK9 protein_coding   21.06517 19.1216 22.29827 0.7399486 0.2506317 0.2216206 4.821481 3.307751 5.869489 0.2916464 0.9374052 0.8254851 0.2271333 0.173100 0.262625 0.089525 6.783167e-01 2.346277e-10 FALSE TRUE
MSTRG.24039.6 ENSG00000050748 No_inf pgKDN_inf MAPK9 protein_coding   21.06517 19.1216 22.29827 0.7399486 0.2506317 0.2216206 2.136183 5.757959 0.000000 0.7298735 0.0000000 -9.1719171 0.1106750 0.302525 0.000000 -0.302525 2.346277e-10 2.346277e-10 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000050748 E001 0.0000000       5 180233143 180233593 451 -      
ENSG00000050748 E002 0.4891593 0.0606137797 0.913544892   5 180233594 180233617 24 - 0.181 0.165 -0.156
ENSG00000050748 E003 1.7146354 0.0339097408 0.845669941 0.94509661 5 180233618 180233678 61 - 0.448 0.419 -0.156
ENSG00000050748 E004 32.8583501 0.0030477301 0.002365680 0.02892204 5 180233679 180234365 687 - 1.429 1.596 0.575
ENSG00000050748 E005 4.2980240 0.0039722085 0.851757168 0.94757268 5 180234366 180234449 84 - 0.710 0.733 0.092
ENSG00000050748 E006 99.9408195 0.0002501849 0.007329003 0.06513139 5 180234450 180236186 1737 - 1.961 2.034 0.244
ENSG00000050748 E007 56.3685419 0.0005350694 0.369450278 0.65762965 5 180236187 180236525 339 - 1.776 1.741 -0.119
ENSG00000050748 E008 10.4045328 0.0070186433 0.577223765 0.81104563 5 180236526 180236526 1 - 1.083 1.031 -0.190
ENSG00000050748 E009 2.4430296 0.0069183105 0.499986920 0.76019210 5 180236527 180236531 5 - 0.585 0.489 -0.446
ENSG00000050748 E010 3.7504221 0.0048284811 0.007360547 0.06531487 5 180236532 180238308 1777 - 0.449 0.802 1.560
ENSG00000050748 E011 0.1272623 0.0123321353 0.598872725   5 180238309 180238331 23 - 0.000 0.091 10.148
ENSG00000050748 E012 19.0405479 0.0008867039 0.072598615 0.27352663 5 180238332 180238403 72 - 1.361 1.242 -0.416
ENSG00000050748 E013 16.3722117 0.0143542333 0.253992556 0.54559640 5 180239924 180239987 64 - 1.287 1.193 -0.329
ENSG00000050748 E014 24.1233914 0.0006544712 0.405643882 0.68833366 5 180241031 180241155 125 - 1.425 1.375 -0.171
ENSG00000050748 E015 6.9822978 0.0027681270 0.597462145 0.82331367 5 180242573 180242577 5 - 0.929 0.875 -0.207
ENSG00000050748 E016 29.9223344 0.0004764319 0.147452877 0.40885996 5 180242578 180242727 150 - 1.445 1.522 0.262
ENSG00000050748 E017 16.1954904 0.0008862545 0.928278112 0.97874517 5 180242728 180242755 28 - 1.238 1.230 -0.025
ENSG00000050748 E018 0.8795680 0.0138371553 0.067776452 0.26271778 5 180242756 180242900 145 - 0.100 0.379 2.429
ENSG00000050748 E019 2.8399241 0.0063315189 0.436374242 0.71280539 5 180246028 180246544 517 - 0.522 0.628 0.481
ENSG00000050748 E020 11.2443260 0.0020487148 0.057760351 0.24046453 5 180246545 180247438 894 - 0.991 1.153 0.589
ENSG00000050748 E021 20.2024045 0.0035654727 0.380179263 0.66675004 5 180247439 180247510 72 - 1.356 1.296 -0.209
ENSG00000050748 E022 0.0000000       5 180247663 180247728 66 -      
ENSG00000050748 E023 0.2441377 0.0161427218 0.933517293   5 180247855 180247926 72 - 0.100 0.091 -0.156
ENSG00000050748 E024 23.0223247 0.0007026685 0.375007228 0.66263604 5 180248973 180249138 166 - 1.407 1.353 -0.187
ENSG00000050748 E025 0.3806233 0.0158291894 0.125344523   5 180253507 180253677 171 - 0.000 0.229 11.641
ENSG00000050748 E026 17.2378288 0.0008951340 0.218436014 0.50504257 5 180261684 180261822 139 - 1.304 1.218 -0.300
ENSG00000050748 E027 0.0000000       5 180262957 180263089 133 -      
ENSG00000050748 E028 9.1646327 0.0015647135 0.300511103 0.59334331 5 180264781 180264839 59 - 1.054 0.960 -0.349
ENSG00000050748 E029 0.0000000       5 180264840 180264842 3 -      
ENSG00000050748 E030 17.1955846 0.0072414593 0.115635510 0.35848104 5 180269280 180269409 130 - 1.320 1.200 -0.423
ENSG00000050748 E031 1.9808994 0.0128904271 0.439624274 0.71555033 5 180279796 180280036 241 - 0.407 0.521 0.581
ENSG00000050748 E032 18.6435267 0.0151055167 0.101162097 0.33218122 5 180280440 180280608 169 - 1.361 1.224 -0.478
ENSG00000050748 E033 3.0312532 0.0057110179 0.099498864 0.32952851 5 180286975 180287067 93 - 0.710 0.489 -0.986
ENSG00000050748 E034 9.2860821 0.0122815825 0.404767163 0.68747322 5 180291848 180292099 252 - 1.054 0.971 -0.308

Help

Please Click HERE to learn more details about the results from DEXseq.