ENSG00000051382

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000462294 ENSG00000051382 No_inf pgKDN_inf PIK3CB protein_coding protein_coding 12.91532 9.782902 14.7422 1.2044 1.589177 0.5911214 0.3536734 1.061020 0.0000000 1.061020 0.0000000 -6.742842 0.02642500 0.079275 0.00000 -0.079275 0.82291049 0.01521582 FALSE FALSE
ENST00000469284 ENSG00000051382 No_inf pgKDN_inf PIK3CB protein_coding nonsense_mediated_decay 12.91532 9.782902 14.7422 1.2044 1.589177 0.5911214 2.2110949 1.159944 2.4406161 1.159944 0.8675456 1.066705 0.16636667 0.132750 0.15580 0.023050 0.53706785 0.01521582 FALSE TRUE
ENST00000477593 ENSG00000051382 No_inf pgKDN_inf PIK3CB protein_coding protein_coding 12.91532 9.782902 14.7422 1.2044 1.589177 0.5911214 5.4991520 3.533509 8.7665525 0.756720 0.2556056 1.308476 0.43755000 0.398100 0.61605 0.217950 0.55179155 0.01521582 FALSE TRUE
ENST00000483968 ENSG00000051382 No_inf pgKDN_inf PIK3CB protein_coding protein_coding 12.91532 9.782902 14.7422 1.2044 1.589177 0.5911214 0.7395011 0.000000 0.8397578 0.000000 0.4848487 6.408980 0.05105000 0.000000 0.05280 0.052800 0.54292371 0.01521582 FALSE FALSE
ENST00000544716 ENSG00000051382 No_inf pgKDN_inf PIK3CB protein_coding protein_coding 12.91532 9.782902 14.7422 1.2044 1.589177 0.5911214 1.1519723 2.790470 0.0000000 1.111625 0.0000000 -8.129525 0.10640000 0.272700 0.00000 -0.272700 0.01521582 0.01521582 FALSE TRUE
MSTRG.20815.17 ENSG00000051382 No_inf pgKDN_inf PIK3CB protein_coding   12.91532 9.782902 14.7422 1.2044 1.589177 0.5911214 0.6852295 0.000000 1.2856378 0.000000 0.8807990 7.017519 0.04250833 0.000000 0.07800 0.078000 0.54438295 0.01521582   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000051382 E001 0.1272623 0.0123618610 0.386045237   3 138652698 138652698 1 - 0.000 0.109 9.305
ENSG00000051382 E002 1.8710075 0.0129228455 0.015987133 0.10964795 3 138652699 138654017 1319 - 0.264 0.618 1.908
ENSG00000051382 E003 0.0000000       3 138654018 138654019 2 -      
ENSG00000051382 E004 0.0000000       3 138654020 138654021 2 -      
ENSG00000051382 E005 1.4617490 0.0311042926 0.981022138 0.99804343 3 138654022 138654067 46 - 0.392 0.386 -0.037
ENSG00000051382 E006 59.0130974 0.0004624974 0.370411119 0.65872307 3 138654068 138655087 1020 - 1.763 1.790 0.089
ENSG00000051382 E007 8.3185690 0.0017337515 0.274761616 0.56819113 3 138655088 138655149 62 - 0.921 1.019 0.364
ENSG00000051382 E008 31.1143517 0.0014642597 0.304341010 0.59776824 3 138655150 138655526 377 - 1.482 1.530 0.165
ENSG00000051382 E009 13.9436382 0.0010273923 0.171571063 0.44413313 3 138656142 138656274 133 - 1.126 1.223 0.348
ENSG00000051382 E010 0.1271363 0.0123556025 0.386038847   3 138657283 138657689 407 - 0.000 0.109 11.847
ENSG00000051382 E011 10.3626782 0.0013520989 0.001170080 0.01687806 3 138657690 138657835 146 - 0.910 1.185 1.005
ENSG00000051382 E012 5.7685769 0.0058745831 0.129691196 0.38201884 3 138663906 138663959 54 - 0.749 0.911 0.633
ENSG00000051382 E013 6.2527349 0.0030523433 0.198095658 0.47949426 3 138663960 138664029 70 - 0.795 0.926 0.506
ENSG00000051382 E014 12.7727459 0.0011817093 0.014175647 0.10109075 3 138665036 138665203 168 - 1.044 1.231 0.671
ENSG00000051382 E015 6.8898671 0.0026855244 0.045360817 0.20831350 3 138681967 138681983 17 - 0.795 0.994 0.759
ENSG00000051382 E016 11.8182103 0.0012134970 0.948668166 0.98676200 3 138681984 138682045 62 - 1.105 1.105 -0.001
ENSG00000051382 E017 0.1186381 0.0118978152 0.744130750   3 138682046 138682060 15 - 0.083 0.000 -12.098
ENSG00000051382 E018 10.9246828 0.0374930769 0.481293230 0.74641226 3 138683678 138683787 110 - 1.105 1.030 -0.271
ENSG00000051382 E019 10.4005449 0.0238612350 0.187682195 0.46583301 3 138684625 138684803 179 - 1.112 0.968 -0.525
ENSG00000051382 E020 0.0000000       3 138684804 138685126 323 -      
ENSG00000051382 E021 7.2456069 0.0739416582 0.252652416 0.54411796 3 138688875 138688974 100 - 0.982 0.808 -0.661
ENSG00000051382 E022 9.0450200 0.0178741635 0.026490523 0.15080640 3 138691000 138691143 144 - 1.090 0.845 -0.914
ENSG00000051382 E023 7.0119103 0.0023032525 0.152082578 0.41584067 3 138694786 138694907 122 - 0.962 0.808 -0.589
ENSG00000051382 E024 12.2182747 0.0012203715 0.086562514 0.30489021 3 138698907 138699095 189 - 1.177 1.030 -0.530
ENSG00000051382 E025 5.0616477 0.0145673730 0.093230346 0.31737274 3 138704443 138704493 51 - 0.862 0.647 -0.873
ENSG00000051382 E026 7.8687751 0.0087241274 0.310813465 0.60397815 3 138707159 138707289 131 - 0.991 0.880 -0.420
ENSG00000051382 E027 0.4807534 0.0223100730 0.501786376   3 138707290 138707621 332 - 0.212 0.109 -1.136
ENSG00000051382 E028 6.7249904 0.0223163935 0.336872898 0.62883611 3 138712208 138712304 97 - 0.837 0.941 0.397
ENSG00000051382 E029 3.5470621 0.0208258255 0.518426074 0.77348729 3 138714468 138714493 26 - 0.617 0.699 0.349
ENSG00000051382 E030 7.4297457 0.0518574312 0.949560237 0.98688788 3 138714494 138714659 166 - 0.921 0.926 0.020
ENSG00000051382 E031 3.5633385 0.0094696390 0.164463364 0.43377021 3 138714660 138714719 60 - 0.571 0.746 0.749
ENSG00000051382 E032 2.2218934 0.0697352082 0.164286276 0.43355757 3 138733361 138733371 11 - 0.392 0.618 1.102
ENSG00000051382 E033 4.8954695 0.0034310590 0.310206057 0.60347331 3 138733372 138733438 67 - 0.715 0.827 0.449
ENSG00000051382 E034 11.3480506 0.0536937581 0.169739770 0.44178867 3 138734634 138734804 171 - 1.158 0.981 -0.643
ENSG00000051382 E035 8.6946375 0.0017059845 0.046285639 0.21100242 3 138737707 138737886 180 - 1.060 0.863 -0.735
ENSG00000051382 E036 8.2174378 0.0095609897 0.075220308 0.28000083 3 138742558 138742755 198 - 1.035 0.845 -0.713
ENSG00000051382 E037 1.9253865 0.0069026856 0.160664387 0.42865561 3 138742756 138742781 26 - 0.546 0.331 -1.136
ENSG00000051382 E038 1.7976235 0.0075054674 0.074072965 0.27728007 3 138755754 138755756 3 - 0.546 0.269 -1.551
ENSG00000051382 E039 7.2125753 0.0020035008 0.006231404 0.05801563 3 138755757 138755979 223 - 1.018 0.723 -1.136
ENSG00000051382 E040 1.8304772 0.0588601805 0.760218545 0.90617545 3 138759173 138759174 2 - 0.427 0.477 0.256
ENSG00000051382 E041 6.5723683 0.0038767027 0.857939161 0.95043834 3 138759175 138759359 185 - 0.887 0.863 -0.092
ENSG00000051382 E042 0.2447669 0.0163262342 0.800424455   3 138760782 138760816 35 - 0.083 0.109 0.449
ENSG00000051382 E043 0.0000000       3 138770051 138770117 67 -      
ENSG00000051382 E044 0.0000000       3 138770118 138770555 438 -      
ENSG00000051382 E045 0.2459655 0.0164060247 0.800631129   3 138773282 138773334 53 - 0.083 0.109 0.449
ENSG00000051382 E046 0.2362687 0.0157201237 0.374631653   3 138788876 138788936 61 - 0.152 0.000 -13.003
ENSG00000051382 E047 3.8747504 0.0074909868 0.389683956 0.67532638 3 138796463 138796567 105 - 0.732 0.618 -0.484
ENSG00000051382 E048 1.9504039 0.0081460590 0.885185491 0.96136748 3 138834695 138834928 234 - 0.460 0.477 0.086

Help

Please Click HERE to learn more details about the results from DEXseq.