ENSG00000051523

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261623 ENSG00000051523 No_inf pgKDN_inf CYBA protein_coding protein_coding 1876.534 1431.489 2006.117 21.66726 19.94598 0.4868861 1786.539 1300.877 1950.762 19.40811 14.59551 0.5845494 0.947625 0.908775 0.9725 0.063725 3.241828e-36 3.241828e-36 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000051523 E001 1.207881 1.011307e-01 3.718629e-01 6.597949e-01 16 88643275 88643288 14 - 0.411 0.255 -0.976
ENSG00000051523 E002 3.621738 5.062211e-03 8.189749e-02 2.944510e-01 16 88643289 88643289 1 - 0.758 0.531 -0.978
ENSG00000051523 E003 989.388305 8.795886e-05 2.990524e-05 8.629797e-04 16 88643290 88643513 224 - 3.014 2.973 -0.136
ENSG00000051523 E004 709.776843 3.919480e-05 1.683421e-03 2.234645e-02 16 88643514 88643539 26 - 2.868 2.833 -0.117
ENSG00000051523 E005 824.340707 3.344781e-05 3.493981e-02 1.787897e-01 16 88643540 88643571 32 - 2.926 2.905 -0.071
ENSG00000051523 E006 5.832410 2.536012e-03 2.400612e-03 2.922677e-02 16 88643572 88643581 10 - 0.641 0.979 1.337
ENSG00000051523 E007 39.995991 5.496230e-04 4.844519e-23 1.707740e-20 16 88643582 88644022 441 - 1.304 1.805 1.717
ENSG00000051523 E008 26.793998 5.629945e-03 1.548895e-13 2.247753e-11 16 88644023 88644178 156 - 1.133 1.637 1.750
ENSG00000051523 E009 21.058136 8.607042e-04 5.389563e-21 1.571247e-18 16 88644179 88644247 69 - 0.902 1.574 2.388
ENSG00000051523 E010 15.066772 9.523762e-04 6.880513e-18 1.559217e-15 16 88644248 88644274 27 - 0.722 1.446 2.654
ENSG00000051523 E011 10.402459 1.335279e-03 1.976649e-11 2.158068e-09 16 88644275 88644287 13 - 0.641 1.281 2.425
ENSG00000051523 E012 60.196343 2.758871e-04 2.240157e-52 4.315022e-49 16 88644288 88644741 454 - 1.354 2.015 2.248
ENSG00000051523 E013 8.123770 1.689445e-03 1.023996e-07 5.964168e-06 16 88644742 88644821 80 - 0.618 1.164 2.109
ENSG00000051523 E014 35.873406 3.699684e-04 5.145172e-29 2.831629e-26 16 88644822 88645086 265 - 1.174 1.785 2.104
ENSG00000051523 E015 52.597502 5.444405e-04 1.685263e-47 2.330589e-44 16 88645087 88645429 343 - 1.279 1.962 2.332
ENSG00000051523 E016 64.483918 2.198175e-04 1.126876e-48 1.736483e-45 16 88645430 88645964 535 - 1.429 2.033 2.046
ENSG00000051523 E017 19.417002 1.152621e-02 9.108360e-08 5.357146e-06 16 88645965 88646115 151 - 1.046 1.485 1.546
ENSG00000051523 E018 691.715740 3.663255e-05 5.690160e-01 8.061496e-01 16 88646116 88646131 16 - 2.843 2.837 -0.020
ENSG00000051523 E019 680.804198 4.432002e-05 3.018579e-02 1.634251e-01 16 88646132 88646140 9 - 2.845 2.820 -0.082
ENSG00000051523 E020 1132.600696 3.646404e-05 2.595547e-03 3.095574e-02 16 88646141 88646197 57 - 3.066 3.040 -0.087
ENSG00000051523 E021 23.020912 2.793571e-03 1.190359e-18 2.866107e-16 16 88646198 88646519 322 - 0.980 1.601 2.186
ENSG00000051523 E022 6.442417 2.370603e-03 2.087770e-03 2.640755e-02 16 88646520 88646603 84 - 0.683 1.014 1.286
ENSG00000051523 E023 12.117414 1.109912e-03 6.135437e-04 1.022270e-02 16 88646604 88646754 151 - 0.959 1.243 1.028
ENSG00000051523 E024 1039.785719 3.243705e-05 4.099483e-04 7.462083e-03 16 88646755 88646787 33 - 3.032 3.000 -0.107
ENSG00000051523 E025 1389.655825 5.958871e-05 1.071213e-01 3.430060e-01 16 88646788 88646838 51 - 3.149 3.136 -0.042
ENSG00000051523 E026 66.823843 2.541727e-04 2.097967e-04 4.351991e-03 16 88646839 88646968 130 - 1.759 1.898 0.467
ENSG00000051523 E027 16.735941 1.498041e-02 2.850480e-02 1.580851e-01 16 88646969 88647100 132 - 1.147 1.338 0.672
ENSG00000051523 E028 1123.806704 7.944006e-04 3.124210e-01 6.058356e-01 16 88647101 88647175 75 - 3.057 3.044 -0.043
ENSG00000051523 E029 697.754520 4.741609e-05 3.545422e-02 1.802421e-01 16 88648045 88648114 70 - 2.855 2.831 -0.078
ENSG00000051523 E030 4.695863 3.168212e-03 3.438379e-02 1.771214e-01 16 88650253 88650314 62 - 0.618 0.869 1.022
ENSG00000051523 E031 649.132680 6.876861e-04 3.564034e-01 6.461698e-01 16 88650956 88651083 128 - 2.819 2.805 -0.048

Help

Please Click HERE to learn more details about the results from DEXseq.