ENSG00000054967

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000064780 ENSG00000054967 No_inf pgKDN_inf RELT protein_coding protein_coding 22.98072 20.20091 24.32392 0.565783 1.389973 0.2678344 18.492393 15.5831950 21.6159894 0.6378986 0.8647597 0.4718496 0.80260833 0.770925 0.891450 0.120525 0.12011794 0.03034151 FALSE TRUE
ENST00000393580 ENSG00000054967 No_inf pgKDN_inf RELT protein_coding protein_coding 22.98072 20.20091 24.32392 0.565783 1.389973 0.2678344 1.300175 0.2995459 0.3615631 0.2995459 0.3615631 0.2634540 0.05629167 0.015750 0.016600 0.000850 1.00000000 0.03034151 FALSE TRUE
ENST00000539134 ENSG00000054967 No_inf pgKDN_inf RELT protein_coding retained_intron 22.98072 20.20091 24.32392 0.565783 1.389973 0.2678344 1.115667 2.4634537 0.3683874 0.2846673 0.2397632 -2.7085909 0.05221667 0.122575 0.014300 -0.108275 0.03034151 0.03034151   FALSE
ENST00000545886 ENSG00000054967 No_inf pgKDN_inf RELT protein_coding retained_intron 22.98072 20.20091 24.32392 0.565783 1.389973 0.2678344 1.251868 1.2684318 0.7420681 0.1275187 0.1916033 -0.7654401 0.05544167 0.062675 0.030725 -0.031950 0.64857059 0.03034151 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000054967 E001 0.3646686 0.1255933223 6.351064e-01   11 73376399 73376399 1 + 0.170 0.097 -0.938
ENSG00000054967 E002 0.4915226 0.0174098373 9.694502e-01   11 73376400 73376407 8 + 0.170 0.176 0.062
ENSG00000054967 E003 5.2147182 0.0035856732 1.202713e-01 0.366750426 11 73376408 73376499 92 + 0.873 0.699 -0.693
ENSG00000054967 E004 0.0000000       11 73376668 73376869 202 +      
ENSG00000054967 E005 0.7274471 0.0140740646 4.399478e-01 0.715780784 11 73384346 73384416 71 + 0.292 0.176 -0.938
ENSG00000054967 E006 0.3814089 0.4994621187 2.664745e-01   11 73384536 73384621 86 + 0.000 0.243 10.867
ENSG00000054967 E007 8.9406812 0.0062957034 5.269754e-03 0.051573023 11 73389112 73389181 70 + 1.113 0.845 -0.997
ENSG00000054967 E008 11.5219612 0.0024979559 1.735956e-02 0.115389505 11 73390551 73390625 75 + 1.187 0.989 -0.716
ENSG00000054967 E009 19.1842142 0.0007458324 5.093827e-01 0.767282787 11 73390755 73390921 167 + 1.325 1.285 -0.141
ENSG00000054967 E010 13.9364100 0.0314351657 8.149621e-01 0.932395521 11 73391144 73391223 80 + 1.187 1.161 -0.090
ENSG00000054967 E011 0.6166128 0.0147383020 6.270920e-01 0.839813460 11 73391982 73392210 229 + 0.170 0.243 0.647
ENSG00000054967 E012 34.1408202 0.0004674866 7.131275e-02 0.270554906 11 73392211 73392468 258 + 1.587 1.502 -0.290
ENSG00000054967 E013 6.5432089 0.0029924664 1.025091e-01 0.334751416 11 73392469 73393243 775 + 0.780 0.954 0.670
ENSG00000054967 E014 6.9828747 0.0019186743 7.701071e-05 0.001910531 11 73393244 73393683 440 + 0.639 1.061 1.647
ENSG00000054967 E015 2.9941560 0.0055948737 1.035695e-02 0.082133753 11 73393684 73393836 153 + 0.387 0.740 1.647
ENSG00000054967 E016 22.3876399 0.0023813972 9.857089e-01 0.999078879 11 73393837 73393917 81 + 1.367 1.371 0.015
ENSG00000054967 E017 0.6339197 0.0384705905 2.003762e-02 0.127097394 11 73393918 73394235 318 + 0.000 0.352 12.327
ENSG00000054967 E018 26.0700682 0.0006064797 8.396938e-01 0.942517944 11 73394236 73394317 82 + 1.425 1.439 0.048
ENSG00000054967 E019 0.1272623 0.0123330993 5.186730e-01   11 73394318 73394476 159 + 0.000 0.097 10.257
ENSG00000054967 E020 52.1669574 0.0003070737 2.689624e-01 0.562583652 11 73394477 73394734 258 + 1.745 1.706 -0.134
ENSG00000054967 E021 2.2145611 0.0782495906 6.095676e-01 0.830174629 11 73394735 73395086 352 + 0.465 0.544 0.383
ENSG00000054967 E022 36.0146336 0.0004813926 7.426394e-01 0.898327471 11 73395087 73395285 199 + 1.559 1.577 0.062
ENSG00000054967 E023 69.2697153 0.0005012981 2.502040e-02 0.145508969 11 73395444 73397474 2031 + 1.806 1.882 0.257

Help

Please Click HERE to learn more details about the results from DEXseq.