ENSG00000058063

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000323116 ENSG00000058063 No_inf pgKDN_inf ATP11B protein_coding protein_coding 16.82656 15.31782 18.54619 0.5949929 0.8528005 0.2757483 6.3264947 3.062366 9.623989 1.2581148 2.0303273 1.6487833 0.37275833 0.194975 0.525500 0.330525 3.555058e-01 3.533709e-11 FALSE TRUE
ENST00000466758 ENSG00000058063 No_inf pgKDN_inf ATP11B protein_coding nonsense_mediated_decay 16.82656 15.31782 18.54619 0.5949929 0.8528005 0.2757483 2.0390142 5.393205 0.000000 0.4172350 0.0000000 -9.0776717 0.13330833 0.352300 0.000000 -0.352300 3.533709e-11 3.533709e-11 TRUE TRUE
ENST00000482070 ENSG00000058063 No_inf pgKDN_inf ATP11B protein_coding protein_coding 16.82656 15.31782 18.54619 0.5949929 0.8528005 0.2757483 0.9434007 0.000000 1.251876 0.0000000 1.2518761 6.9794264 0.04636667 0.000000 0.059575 0.059575 8.509867e-01 3.533709e-11 FALSE FALSE
ENST00000490303 ENSG00000058063 No_inf pgKDN_inf ATP11B protein_coding retained_intron 16.82656 15.31782 18.54619 0.5949929 0.8528005 0.2757483 1.3789444 0.543606 1.419253 0.5436060 0.8363305 1.3683302 0.08418333 0.038225 0.078600 0.040375 8.272095e-01 3.533709e-11 FALSE TRUE
ENST00000491699 ENSG00000058063 No_inf pgKDN_inf ATP11B protein_coding protein_coding 16.82656 15.31782 18.54619 0.5949929 0.8528005 0.2757483 0.7015826 2.104748 0.000000 0.7780719 0.0000000 -7.7243419 0.04445833 0.133375 0.000000 -0.133375 3.016657e-02 3.533709e-11 FALSE TRUE
MSTRG.21145.4 ENSG00000058063 No_inf pgKDN_inf ATP11B protein_coding   16.82656 15.31782 18.54619 0.5949929 0.8528005 0.2757483 3.6329425 3.467850 3.832639 1.3170881 1.6157969 0.1439016 0.21527500 0.235375 0.206450 -0.028925 9.880477e-01 3.533709e-11 TRUE TRUE
MSTRG.21145.6 ENSG00000058063 No_inf pgKDN_inf ATP11B protein_coding   16.82656 15.31782 18.54619 0.5949929 0.8528005 0.2757483 1.0226683 0.000000 1.951723 0.0000000 0.9871008 7.6159776 0.05911667 0.000000 0.103900 0.103900 1.458833e-01 3.533709e-11 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000058063 E001 0.2352613 0.2559570794 4.139624e-01   3 182793500 182793502 3 + 0.154 0.000 -9.886
ENSG00000058063 E002 0.2352613 0.2559570794 4.139624e-01   3 182793503 182793503 1 + 0.154 0.000 -12.106
ENSG00000058063 E003 4.4380179 0.0701160710 5.857162e-02 2.424502e-01 3 182793504 182793786 283 + 0.844 0.547 -1.243
ENSG00000058063 E004 0.9627093 0.3661622700 4.308637e-01 7.086115e-01 3 182820260 182820264 5 + 0.358 0.193 -1.192
ENSG00000058063 E005 4.2936451 0.0074676149 9.521118e-04 1.444681e-02 3 182820265 182820376 112 + 0.870 0.429 -1.928
ENSG00000058063 E006 5.3089415 0.0049562845 6.968069e-02 2.669480e-01 3 182828120 182828209 90 + 0.882 0.667 -0.860
ENSG00000058063 E007 4.5866234 0.0053475638 7.796904e-02 2.856393e-01 3 182829672 182829752 81 + 0.830 0.611 -0.901
ENSG00000058063 E008 0.1176306 0.0117416877 7.102304e-01   3 182833673 182833874 202 + 0.084 0.000 -11.825
ENSG00000058063 E009 7.0023292 0.0020695451 6.137499e-02 2.487936e-01 3 182836035 182836142 108 + 0.980 0.782 -0.758
ENSG00000058063 E010 4.8466550 0.0073927138 4.835695e-01 7.480307e-01 3 182836342 182836353 12 + 0.802 0.717 -0.343
ENSG00000058063 E011 10.4522351 0.0022343658 6.576064e-01 8.568025e-01 3 182836354 182836470 117 + 1.075 1.034 -0.149
ENSG00000058063 E012 0.0000000       3 182836471 182836624 154 +      
ENSG00000058063 E013 4.5013773 0.0671307356 7.499953e-01 9.014575e-01 3 182837071 182837116 46 + 0.756 0.717 -0.158
ENSG00000058063 E014 5.9742732 0.0036534930 9.752008e-01 9.955421e-01 3 182837117 182837174 58 + 0.844 0.838 -0.021
ENSG00000058063 E015 6.0716524 0.0024184091 4.690852e-01 7.370862e-01 3 182842075 182842122 48 + 0.882 0.801 -0.312
ENSG00000058063 E016 7.3986390 0.0429008246 4.014728e-01 6.845944e-01 3 182845458 182845522 65 + 0.970 0.856 -0.433
ENSG00000058063 E017 7.4782366 0.0420658133 4.443407e-02 2.061334e-01 3 182848476 182848557 82 + 1.026 0.761 -1.012
ENSG00000058063 E018 10.5966358 0.0107641557 2.495847e-03 3.006723e-02 3 182857878 182858023 146 + 1.173 0.872 -1.105
ENSG00000058063 E019 2.8898510 0.0135789549 7.478716e-02 2.789661e-01 3 182858024 182858028 5 + 0.685 0.429 -1.191
ENSG00000058063 E020 11.8500013 0.0052681901 2.616595e-02 1.496642e-01 3 182859162 182859359 198 + 1.185 0.987 -0.718
ENSG00000058063 E021 6.3297704 0.0360886284 7.331087e-01 8.938910e-01 3 182865456 182865526 71 + 0.882 0.838 -0.169
ENSG00000058063 E022 13.8344333 0.0010357280 2.442567e-01 5.343884e-01 3 182865527 182865698 172 + 1.208 1.116 -0.329
ENSG00000058063 E023 10.9993094 0.0013229534 4.912732e-02 2.185625e-01 3 182866268 182866443 176 + 1.147 0.974 -0.630
ENSG00000058063 E024 6.2241316 0.0429003398 5.984015e-01 8.239306e-01 3 182867376 182867444 69 + 0.830 0.888 0.225
ENSG00000058063 E025 7.8754904 0.0283096901 4.079183e-01 6.903253e-01 3 182869078 182869151 74 + 0.989 0.888 -0.378
ENSG00000058063 E026 10.9588091 0.0013062982 2.134796e-03 2.683247e-02 3 182869228 182869331 104 + 1.179 0.904 -1.006
ENSG00000058063 E027 18.1358006 0.0007366231 8.782028e-03 7.369689e-02 3 182872356 182872537 182 + 1.353 1.169 -0.649
ENSG00000058063 E028 15.5779456 0.0009324360 6.977773e-01 8.766455e-01 3 182873812 182873965 154 + 1.231 1.201 -0.107
ENSG00000058063 E029 7.5593111 0.0018470723 9.433413e-01 9.842603e-01 3 182873966 182874015 50 + 0.928 0.933 0.020
ENSG00000058063 E030 6.1677082 0.0022240139 1.576248e-01 4.242522e-01 3 182879496 182879538 43 + 0.917 0.761 -0.606
ENSG00000058063 E031 9.9687133 0.0170605244 7.993189e-01 9.247095e-01 3 182879539 182879649 111 + 1.051 1.023 -0.103
ENSG00000058063 E032 7.7692131 0.0342758570 6.091125e-01 8.299490e-01 3 182880879 182880947 69 + 0.970 0.904 -0.247
ENSG00000058063 E033 5.7873298 0.0024381060 4.858126e-02 2.171001e-01 3 182880948 182880981 34 + 0.917 0.693 -0.886
ENSG00000058063 E034 12.5686947 0.0013680727 1.819269e-02 1.191286e-01 3 182884753 182884898 146 + 1.208 1.011 -0.711
ENSG00000058063 E035 10.8685743 0.0012356846 5.744795e-01 8.094673e-01 3 182885951 182886010 60 + 1.051 1.097 0.167
ENSG00000058063 E036 20.4720105 0.0007124921 2.871237e-02 1.586978e-01 3 182887586 182887713 128 + 1.262 1.400 0.481
ENSG00000058063 E037 16.5285265 0.0153946405 2.635187e-01 5.565935e-01 3 182889410 182889548 139 + 1.197 1.290 0.330
ENSG00000058063 E038 9.4818103 0.0306928548 5.043506e-01 7.635055e-01 3 182896700 182896765 66 + 1.051 0.974 -0.284
ENSG00000058063 E039 0.0000000       3 182897302 182897302 1 +      
ENSG00000058063 E040 17.1551275 0.0160696662 7.226452e-01 8.885940e-01 3 182897303 182897406 104 + 1.272 1.237 -0.123
ENSG00000058063 E041 15.8433311 0.0126564678 8.664341e-01 9.539942e-01 3 182898607 182898684 78 + 1.220 1.230 0.037
ENSG00000058063 E042 15.9728576 0.0009317012 7.859049e-01 9.174873e-01 3 182898685 182898772 88 + 1.220 1.237 0.062
ENSG00000058063 E043 0.2455571 0.0162136987 8.296216e-01   3 182902481 182902566 86 + 0.084 0.107 0.394
ENSG00000058063 E044 0.2541163 0.0159513915 1.610257e-01   3 182905794 182905919 126 + 0.000 0.193 12.251
ENSG00000058063 E045 0.5077596 0.0150511459 2.269524e-02 1.371786e-01 3 182908459 182908505 47 + 0.000 0.327 13.193
ENSG00000058063 E046 16.1050345 0.0113946252 7.767098e-02 2.851672e-01 3 182913861 182913994 134 + 1.292 1.143 -0.526
ENSG00000058063 E047 22.3337319 0.0007339472 6.390443e-01 8.465030e-01 3 182913995 182915372 1378 + 1.353 1.380 0.093
ENSG00000058063 E048 233.7977252 0.0001933939 3.852811e-18 8.956789e-16 3 182918023 182921629 3607 + 2.301 2.439 0.458

Help

Please Click HERE to learn more details about the results from DEXseq.