ENSG00000059691

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263985 ENSG00000059691 No_inf pgKDN_inf GATB protein_coding protein_coding 7.059109 7.237046 7.380465 1.387428 1.362731 0.02827211 0.8116073 1.6350809 0.6753948 0.5787750 0.3978729 -1.2631514 0.13567500 0.255050 0.133625 -0.121425 7.556013e-01 3.755121e-06 FALSE TRUE
ENST00000503160 ENSG00000059691 No_inf pgKDN_inf GATB protein_coding nonsense_mediated_decay 7.059109 7.237046 7.380465 1.387428 1.362731 0.02827211 1.4728238 1.2363663 0.6848978 0.7140959 0.6848978 -0.8428554 0.22605000 0.206125 0.083000 -0.123125 8.275875e-01 3.755121e-06 FALSE TRUE
ENST00000505211 ENSG00000059691 No_inf pgKDN_inf GATB protein_coding retained_intron 7.059109 7.237046 7.380465 1.387428 1.362731 0.02827211 0.5951346 0.8710077 0.9143963 0.8710077 0.9143963 0.0693568 0.05401667 0.077075 0.084975 0.007900 1.000000e+00 3.755121e-06 FALSE FALSE
ENST00000507592 ENSG00000059691 No_inf pgKDN_inf GATB protein_coding protein_coding_CDS_not_defined 7.059109 7.237046 7.380465 1.387428 1.362731 0.02827211 0.2841152 0.0000000 0.8523455 0.0000000 0.8523455 6.4301941 0.02640000 0.000000 0.079200 0.079200 8.350142e-01 3.755121e-06 FALSE TRUE
ENST00000510720 ENSG00000059691 No_inf pgKDN_inf GATB protein_coding nonsense_mediated_decay 7.059109 7.237046 7.380465 1.387428 1.362731 0.02827211 1.5579752 2.7851359 0.6071784 1.1676063 0.6071784 -2.1791589 0.20341667 0.348125 0.073575 -0.274550 3.291928e-01 3.755121e-06 TRUE TRUE
ENST00000515812 ENSG00000059691 No_inf pgKDN_inf GATB protein_coding protein_coding 7.059109 7.237046 7.380465 1.387428 1.362731 0.02827211 1.9088652 0.0000000 3.3527777 0.0000000 0.2607682 8.3935096 0.28675833 0.000000 0.501450 0.501450 3.755121e-06 3.755121e-06 FALSE TRUE
ENST00000515884 ENSG00000059691 No_inf pgKDN_inf GATB protein_coding nonsense_mediated_decay 7.059109 7.237046 7.380465 1.387428 1.362731 0.02827211 0.1165853 0.3497560 0.0000000 0.3497560 0.0000000 -5.1689467 0.02146667 0.064400 0.000000 -0.064400 8.544562e-01 3.755121e-06 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000059691 E001 0.4975013 0.015972691 0.332638889   4 151670504 151670837 334 - 0.095 0.239 1.578
ENSG00000059691 E002 0.0000000       4 151670838 151670848 11 -      
ENSG00000059691 E003 0.2459655 0.016371384 0.983632727   4 151670849 151670862 14 - 0.095 0.095 -0.007
ENSG00000059691 E004 0.2459655 0.016371384 0.983632727   4 151670863 151670887 25 - 0.095 0.095 -0.007
ENSG00000059691 E005 1.3785210 0.082393569 0.048204071 0.21611292 4 151670888 151670943 56 - 0.173 0.505 2.163
ENSG00000059691 E006 7.6333350 0.002229658 0.348845925 0.63939457 4 151670944 151671135 192 - 0.882 0.980 0.368
ENSG00000059691 E007 8.7808676 0.001674033 0.264739734 0.55779776 4 151671136 151671302 167 - 1.034 0.945 -0.329
ENSG00000059691 E008 0.2444846 0.016417012 0.980968788   4 151672609 151672761 153 - 0.095 0.095 -0.007
ENSG00000059691 E009 6.8355894 0.002425692 0.349233502 0.63959930 4 151672762 151672896 135 - 0.935 0.852 -0.317
ENSG00000059691 E010 1.2454303 0.254098927 0.387832488 0.67353681 4 151672897 151675888 2992 - 0.240 0.433 1.215
ENSG00000059691 E011 2.9134600 0.005381734 0.190930620 0.47029687 4 151679813 151679891 79 - 0.670 0.505 -0.744
ENSG00000059691 E012 0.0000000       4 151686908 151687083 176 -      
ENSG00000059691 E013 3.8264635 0.004335463 0.232194680 0.52083575 4 151688630 151688736 107 - 0.596 0.751 0.656
ENSG00000059691 E014 2.6029001 0.005569104 0.138032955 0.39539293 4 151688737 151688763 27 - 0.434 0.645 0.993
ENSG00000059691 E015 0.0000000       4 151691658 151691724 67 -      
ENSG00000059691 E016 3.8090571 0.003962748 0.641012897 0.84760172 4 151701329 151701395 67 - 0.647 0.712 0.273
ENSG00000059691 E017 2.1841943 0.006807216 0.312812762 0.60616958 4 151701396 151701456 61 - 0.568 0.433 -0.659
ENSG00000059691 E018 2.1956138 0.006575445 0.593258484 0.82069092 4 151701457 151701518 62 - 0.538 0.470 -0.329
ENSG00000059691 E019 0.2539903 0.016189591 0.252367124   4 151703179 151703341 163 - 0.000 0.173 11.951
ENSG00000059691 E020 0.2533610 0.016186570 0.252339843   4 151703342 151703850 509 - 0.000 0.173 11.951
ENSG00000059691 E021 2.8217933 0.005325257 0.887882627 0.96249596 4 151703851 151703895 45 - 0.568 0.594 0.119
ENSG00000059691 E022 2.2213913 0.006282505 0.375622890 0.66308123 4 151705185 151705229 45 - 0.434 0.567 0.645
ENSG00000059691 E023 2.9461655 0.008228518 0.736926878 0.89569149 4 151705230 151705269 40 - 0.568 0.621 0.234
ENSG00000059691 E024 4.4382830 0.019776594 0.395988850 0.68086147 4 151707988 151708101 114 - 0.670 0.787 0.479
ENSG00000059691 E025 3.6944746 0.004196622 0.508862602 0.76698420 4 151716009 151716131 123 - 0.622 0.712 0.380
ENSG00000059691 E026 0.0000000       4 151716132 151716244 113 -      
ENSG00000059691 E027 3.8088599 0.138670170 0.841146856 0.94305428 4 151716876 151717001 126 - 0.647 0.712 0.274
ENSG00000059691 E028 2.6378599 0.010929946 0.007739275 0.06759677 4 151717002 151717074 73 - 0.714 0.347 -1.772
ENSG00000059691 E029 0.0000000       4 151717075 151717331 257 -      
ENSG00000059691 E030 3.0106419 0.004858711 0.020348683 0.12831690 4 151719425 151719538 114 - 0.734 0.433 -1.369
ENSG00000059691 E031 0.2542726 0.272936247 0.312519714   4 151719539 151721945 2407 - 0.000 0.173 11.952
ENSG00000059691 E032 0.1170040 0.011818836 0.521662157   4 151721946 151722215 270 - 0.095 0.000 -11.070
ENSG00000059691 E033 0.1268540 0.012414033 0.554352252   4 151722216 151724480 2265 - 0.000 0.095 10.951
ENSG00000059691 E034 3.6597286 0.003962418 0.414590907 0.69479371 4 151758772 151758922 151 - 0.714 0.621 -0.394
ENSG00000059691 E035 2.6868531 0.005302197 0.620836671 0.83614356 4 151760807 151761007 201 - 0.596 0.537 -0.270

Help

Please Click HERE to learn more details about the results from DEXseq.