ENSG00000062598

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000290246 ENSG00000062598 No_inf pgKDN_inf ELMO2 protein_coding protein_coding 35.20228 36.95587 36.27835 1.344766 1.77303 -0.02668752 6.389162 4.8424112 6.5331326 0.6781226 1.7282397 0.4312797 0.18443333 0.131800 0.179600 0.047800 0.85566849 0.03547053 FALSE TRUE
ENST00000396391 ENSG00000062598 No_inf pgKDN_inf ELMO2 protein_coding protein_coding 35.20228 36.95587 36.27835 1.344766 1.77303 -0.02668752 3.438184 0.8337547 6.6616385 0.8337547 2.1106090 2.9831455 0.09760000 0.021475 0.179125 0.157650 0.03547053 0.03547053 FALSE TRUE
ENST00000452857 ENSG00000062598 No_inf pgKDN_inf ELMO2 protein_coding protein_coding 35.20228 36.95587 36.27835 1.344766 1.77303 -0.02668752 13.936238 16.9630123 12.7118441 1.2859718 1.6871958 -0.4159348 0.39323333 0.457225 0.350375 -0.106850 0.55465452 0.03547053 FALSE TRUE
ENST00000481852 ENSG00000062598 No_inf pgKDN_inf ELMO2 protein_coding protein_coding_CDS_not_defined 35.20228 36.95587 36.27835 1.344766 1.77303 -0.02668752 1.642433 2.9817617 0.6633435 0.4563303 0.2305943 -2.1515806 0.04591667 0.080725 0.017650 -0.063075 0.11717982 0.03547053 FALSE FALSE
MSTRG.18363.6 ENSG00000062598 No_inf pgKDN_inf ELMO2 protein_coding   35.20228 36.95587 36.27835 1.344766 1.77303 -0.02668752 3.871718 4.4427117 6.0205432 1.6697340 3.0415289 0.4376038 0.10856667 0.120075 0.170900 0.050825 1.00000000 0.03547053 FALSE TRUE
MSTRG.18363.7 ENSG00000062598 No_inf pgKDN_inf ELMO2 protein_coding   35.20228 36.95587 36.27835 1.344766 1.77303 -0.02668752 3.315152 4.3905910 1.5433003 1.6048718 1.5433003 -1.5023605 0.09624167 0.122975 0.044975 -0.078000 0.37422866 0.03547053 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000062598 E001 0.1187032 0.0118644921 0.514627501   20 46366050 46366053 4 - 0.096 0.000 -9.838
ENSG00000062598 E002 0.1187032 0.0118644921 0.514627501   20 46366054 46366054 1 - 0.096 0.000 -12.234
ENSG00000062598 E003 0.1187032 0.0118644921 0.514627501   20 46366055 46366057 3 - 0.096 0.000 -12.234
ENSG00000062598 E004 225.9956304 0.0020907668 0.042783534 0.20161530 20 46366058 46367359 1302 - 2.330 2.377 0.159
ENSG00000062598 E005 36.2016932 0.0004385973 0.610512754 0.83067947 20 46367360 46367560 201 - 1.554 1.584 0.100
ENSG00000062598 E006 22.0933555 0.0007804940 0.647820202 0.85124948 20 46368891 46368968 78 - 1.345 1.378 0.114
ENSG00000062598 E007 6.4503991 0.0030297607 0.019419992 0.12457521 20 46368969 46370442 1474 - 0.718 0.975 0.995
ENSG00000062598 E008 21.8870241 0.0007655264 0.417322161 0.69703179 20 46370443 46370513 71 - 1.383 1.337 -0.159
ENSG00000062598 E009 14.5402756 0.0012546768 0.385714689 0.67161053 20 46370514 46370525 12 - 1.222 1.161 -0.216
ENSG00000062598 E010 26.1282415 0.0006210866 0.655664585 0.85567822 20 46371352 46371459 108 - 1.417 1.447 0.103
ENSG00000062598 E011 26.7748217 0.0006070731 0.286657919 0.58017333 20 46371579 46371691 113 - 1.471 1.416 -0.191
ENSG00000062598 E012 32.2022792 0.0004516594 0.588295330 0.81727656 20 46371806 46371969 164 - 1.533 1.509 -0.079
ENSG00000062598 E013 0.3728195 0.0165996911 0.611974238   20 46372835 46373240 406 - 0.096 0.171 0.954
ENSG00000062598 E014 0.0000000       20 46373241 46373398 158 -      
ENSG00000062598 E015 27.9628183 0.0004777156 0.732756309 0.89374429 20 46373399 46373535 137 - 1.449 1.472 0.080
ENSG00000062598 E016 13.4413488 0.0010317895 0.425708134 0.70473120 20 46374332 46374350 19 - 1.188 1.131 -0.204
ENSG00000062598 E017 19.8515692 0.0006962311 0.968163951 0.99362450 20 46374351 46374437 87 - 1.315 1.322 0.025
ENSG00000062598 E018 7.4914721 0.0018316444 0.639196469 0.84652004 20 46374438 46374440 3 - 0.901 0.952 0.191
ENSG00000062598 E019 20.4870829 0.0006681809 0.673507980 0.86483822 20 46374536 46374640 105 - 1.315 1.346 0.109
ENSG00000062598 E020 17.5208963 0.0008207611 0.996674989 1.00000000 20 46375236 46375285 50 - 1.265 1.269 0.014
ENSG00000062598 E021 19.0752829 0.0007767099 0.455215726 0.72782157 20 46375286 46375370 85 - 1.325 1.280 -0.157
ENSG00000062598 E022 20.4230766 0.0006382547 0.504817808 0.76384690 20 46375668 46375790 123 - 1.350 1.312 -0.133
ENSG00000062598 E023 2.2463524 0.0063004633 0.020872073 0.13020337 20 46376704 46376967 264 - 0.300 0.641 1.761
ENSG00000062598 E024 0.7420473 0.0138056120 0.443539952 0.71834272 20 46379919 46380252 334 - 0.175 0.293 0.954
ENSG00000062598 E025 11.7149413 0.0016988012 0.308027028 0.60127749 20 46380253 46380303 51 - 1.144 1.064 -0.287
ENSG00000062598 E026 10.4008809 0.0013618747 0.759204956 0.90546548 20 46383416 46383467 52 - 1.068 1.046 -0.080
ENSG00000062598 E027 7.3523171 0.0019287247 0.927121787 0.97833620 20 46383468 46383494 27 - 0.915 0.928 0.050
ENSG00000062598 E028 13.4684754 0.0009898620 0.821881142 0.93540724 20 46386124 46386275 152 - 1.167 1.154 -0.046
ENSG00000062598 E029 9.4152074 0.0016997965 0.601676946 0.82575208 20 46387338 46387426 89 - 1.039 0.996 -0.159
ENSG00000062598 E030 6.2200009 0.0024973821 0.399897561 0.68356333 20 46387427 46387431 5 - 0.901 0.816 -0.330
ENSG00000062598 E031 5.9663575 0.0025373567 0.255558437 0.54754256 20 46387432 46387437 6 - 0.901 0.782 -0.461
ENSG00000062598 E032 0.3716209 0.0165677002 0.610788001   20 46387505 46387622 118 - 0.096 0.171 0.954
ENSG00000062598 E033 15.9239725 0.0009508802 0.009156663 0.07586345 20 46389039 46389220 182 - 1.315 1.131 -0.650
ENSG00000062598 E034 3.1558390 0.0058474077 0.203262455 0.48577241 20 46393093 46393143 51 - 0.697 0.533 -0.724
ENSG00000062598 E035 0.0000000       20 46393529 46393601 73 -      
ENSG00000062598 E036 0.0000000       20 46393981 46394048 68 -      
ENSG00000062598 E037 0.0000000       20 46394049 46394089 41 -      
ENSG00000062598 E038 0.0000000       20 46394405 46394503 99 -      
ENSG00000062598 E039 0.0000000       20 46394504 46394532 29 -      
ENSG00000062598 E040 1.6856558 0.0078985786 0.091485189 0.31407780 20 46398697 46398771 75 - 0.542 0.293 -1.368
ENSG00000062598 E041 1.8032864 0.0075391812 0.057501468 0.23974836 20 46406548 46406632 85 - 0.572 0.293 -1.506
ENSG00000062598 E042 0.0000000       20 46432894 46432985 92 -      

Help

Please Click HERE to learn more details about the results from DEXseq.