ENSG00000064601

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372459 ENSG00000064601 No_inf pgKDN_inf CTSA protein_coding protein_coding 251.0319 271.4987 222.3612 3.021582 2.76287 -0.2880281 8.5979 1.102938 14.69408 0.5962903 4.235287 3.7237707 0.03621667 0.004050 0.06560 0.061550 0.0009751681 0.0009751681 FALSE  
ENST00000646241 ENSG00000064601 No_inf pgKDN_inf CTSA protein_coding protein_coding 251.0319 271.4987 222.3612 3.021582 2.76287 -0.2880281 216.3349 244.928627 190.16146 6.8126866 6.391044 -0.3651196 0.86049167 0.902425 0.85485 -0.047575 0.4860676164 0.0009751681 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000064601 E001 0.2533610 1.598524e-02 3.667645e-01   20 45890144 45890253 110 + 0.000 0.152 9.842
ENSG00000064601 E002 0.0000000       20 45890254 45890298 45 +      
ENSG00000064601 E003 0.0000000       20 45890299 45890340 42 +      
ENSG00000064601 E004 0.0000000       20 45890341 45890867 527 +      
ENSG00000064601 E005 0.0000000       20 45890868 45890962 95 +      
ENSG00000064601 E006 0.0000000       20 45890963 45890970 8 +      
ENSG00000064601 E007 0.0000000       20 45890971 45891071 101 +      
ENSG00000064601 E008 0.0000000       20 45891072 45891172 101 +      
ENSG00000064601 E009 0.9777567 7.595078e-02 6.932931e-01 8.746998e-01 20 45891173 45891312 140 + 0.330 0.265 -0.438
ENSG00000064601 E010 1.1062448 5.876181e-02 9.023138e-01 9.687547e-01 20 45891313 45891321 9 + 0.330 0.312 -0.117
ENSG00000064601 E011 1.4790642 3.830773e-02 9.692672e-01 9.936412e-01 20 45891322 45891334 13 + 0.385 0.393 0.047
ENSG00000064601 E012 7.9875617 1.798207e-03 7.184225e-01 8.867152e-01 20 45891335 45891340 6 + 0.967 0.933 -0.127
ENSG00000064601 E013 11.4207667 1.717412e-03 4.606098e-01 7.319790e-01 20 45891341 45891341 1 + 1.122 1.061 -0.221
ENSG00000064601 E014 11.9008934 1.472372e-03 3.239314e-01 6.164978e-01 20 45891342 45891342 1 + 1.149 1.069 -0.290
ENSG00000064601 E015 14.2411133 9.676859e-04 3.699959e-01 6.582668e-01 20 45891343 45891344 2 + 1.215 1.147 -0.239
ENSG00000064601 E016 14.8385914 9.275822e-04 2.233911e-01 5.110224e-01 20 45891345 45891347 3 + 1.244 1.154 -0.319
ENSG00000064601 E017 25.0597781 6.002262e-04 3.597341e-01 6.492185e-01 20 45891348 45891353 6 + 1.439 1.386 -0.184
ENSG00000064601 E018 25.3056785 6.126289e-04 3.512353e-01 6.415865e-01 20 45891354 45891355 2 + 1.444 1.390 -0.186
ENSG00000064601 E019 28.9686517 4.727786e-04 1.936110e-01 4.734196e-01 20 45891356 45891365 10 + 1.510 1.439 -0.243
ENSG00000064601 E020 43.2391323 3.238796e-04 2.060521e-01 4.896336e-01 20 45891366 45891375 10 + 1.671 1.614 -0.192
ENSG00000064601 E021 47.0374892 2.998343e-04 1.605274e-01 4.283751e-01 20 45891376 45891379 4 + 1.709 1.649 -0.205
ENSG00000064601 E022 0.7167763 1.520242e-01 6.785434e-02 2.628566e-01 20 45891380 45891385 6 + 0.385 0.083 -2.761
ENSG00000064601 E023 2.5678365 6.490074e-02 4.572463e-01 7.292511e-01 20 45891386 45891397 12 + 0.616 0.492 -0.576
ENSG00000064601 E024 4.3846183 6.989770e-02 1.561571e-01 4.223336e-01 20 45891398 45891420 23 + 0.844 0.618 -0.925
ENSG00000064601 E025 4.3846183 6.989770e-02 1.561571e-01 4.223336e-01 20 45891421 45891425 5 + 0.844 0.618 -0.925
ENSG00000064601 E026 1.3075204 9.526984e-03 7.863868e-04 1.244512e-02 20 45891426 45891449 24 + 0.585 0.083 -3.761
ENSG00000064601 E027 3.4630073 1.204349e-02 2.364260e-06 9.786187e-05 20 45891450 45891547 98 + 0.910 0.265 -3.083
ENSG00000064601 E028 2.1555546 1.173543e-01 4.513607e-03 4.611420e-02 20 45891548 45891568 21 + 0.722 0.212 -2.762
ENSG00000064601 E029 76.9205281 2.179815e-04 2.441873e-04 4.932583e-03 20 45891569 45891620 52 + 1.954 1.829 -0.420
ENSG00000064601 E030 154.5005271 6.550423e-04 1.888031e-02 1.222109e-01 20 45891621 45891762 142 + 2.219 2.159 -0.200
ENSG00000064601 E031 1.5970735 8.388726e-03 7.863467e-01 9.176781e-01 20 45891763 45891822 60 + 0.433 0.393 -0.216
ENSG00000064601 E032 0.9786630 1.161362e-02 6.679195e-01 8.618078e-01 20 45891823 45891845 23 + 0.330 0.265 -0.439
ENSG00000064601 E033 1.5957765 8.590399e-03 7.863288e-01 9.176781e-01 20 45891846 45891915 70 + 0.433 0.393 -0.216
ENSG00000064601 E034 158.9968697 2.673032e-03 4.698794e-01 7.378582e-01 20 45891916 45892027 112 + 2.209 2.188 -0.071
ENSG00000064601 E035 0.7538810 1.396819e-02 1.860311e-01 4.639584e-01 20 45892028 45892272 245 + 0.109 0.312 1.883
ENSG00000064601 E036 95.0200110 1.922484e-04 1.387192e-01 3.960658e-01 20 45892273 45892305 33 + 2.001 1.956 -0.150
ENSG00000064601 E037 67.8066976 3.025240e-04 1.043015e-01 3.374968e-01 20 45892306 45892323 18 + 1.864 1.805 -0.198
ENSG00000064601 E038 1.3699532 1.178608e-02 3.056744e-01 5.989658e-01 20 45892324 45892397 74 + 0.268 0.428 0.976
ENSG00000064601 E039 65.2088841 2.996618e-04 6.857630e-02 2.643552e-01 20 45892398 45892484 87 + 1.852 1.785 -0.227
ENSG00000064601 E040 0.4801267 1.531356e-02 1.934430e-01   20 45892485 45892724 240 + 0.268 0.083 -2.024
ENSG00000064601 E041 0.0000000       20 45892725 45892880 156 +      
ENSG00000064601 E042 0.0000000       20 45892881 45892887 7 +      
ENSG00000064601 E043 1.0053224 1.627546e-02 7.020682e-02 2.680997e-01 20 45892888 45892978 91 + 0.109 0.393 2.369
ENSG00000064601 E044 0.6244167 1.505190e-02 3.019588e-01 5.951993e-01 20 45892979 45893039 61 + 0.109 0.265 1.561
ENSG00000064601 E045 0.0000000       20 45893040 45893145 106 +      
ENSG00000064601 E046 0.0000000       20 45893146 45893219 74 +      
ENSG00000064601 E047 0.0000000       20 45893220 45893311 92 +      
ENSG00000064601 E048 1.6071449 8.614750e-03 7.769276e-01 9.142698e-01 20 45893312 45893987 676 + 0.385 0.428 0.239
ENSG00000064601 E049 107.0458272 1.656563e-04 4.369090e-01 7.133332e-01 20 45893988 45894072 85 + 2.039 2.017 -0.072
ENSG00000064601 E050 1.5133649 8.764234e-03 9.232268e-03 7.633499e-02 20 45894073 45894649 577 + 0.109 0.520 3.021
ENSG00000064601 E051 213.4599238 9.468769e-05 7.918891e-01 9.204885e-01 20 45894650 45894741 92 + 2.320 2.326 0.023
ENSG00000064601 E052 102.7449931 1.590096e-04 8.111899e-01 9.305245e-01 20 45894823 45894832 10 + 2.003 2.012 0.029
ENSG00000064601 E053 175.1048198 1.092729e-04 4.480244e-01 7.221675e-01 20 45894833 45894901 69 + 2.248 2.232 -0.053
ENSG00000064601 E054 288.5099439 8.520415e-04 1.666391e-01 4.369682e-01 20 45894994 45895133 140 + 2.470 2.443 -0.090
ENSG00000064601 E055 1.2334435 1.010059e-02 8.809714e-01 9.600208e-01 20 45895134 45895138 5 + 0.330 0.354 0.146
ENSG00000064601 E056 42.1674156 3.194642e-04 1.909791e-07 1.046775e-05 20 45895139 45896455 1317 + 1.457 1.715 0.880
ENSG00000064601 E057 17.5559035 2.910126e-02 3.260121e-01 6.184849e-01 20 45896456 45896964 509 + 1.199 1.299 0.352
ENSG00000064601 E058 211.1602239 2.732191e-04 6.220413e-01 8.371179e-01 20 45896965 45897040 76 + 2.312 2.324 0.040
ENSG00000064601 E059 20.0086057 1.017645e-03 6.691605e-04 1.095311e-02 20 45897041 45897625 585 + 1.158 1.397 0.840
ENSG00000064601 E060 4.5186253 4.114065e-03 1.126521e-03 1.643435e-02 20 45897626 45897716 91 + 0.433 0.864 1.883
ENSG00000064601 E061 114.4858265 3.357174e-03 7.309075e-01 8.931254e-01 20 45897717 45897725 9 + 2.046 2.060 0.047
ENSG00000064601 E062 244.2525444 3.382384e-04 1.532835e-01 4.178239e-01 20 45897726 45897806 81 + 2.364 2.394 0.102
ENSG00000064601 E063 6.3693180 2.170980e-03 5.318727e-03 5.179852e-02 20 45897807 45897907 101 + 0.645 0.964 1.262
ENSG00000064601 E064 8.5847906 1.588524e-03 1.149429e-02 8.813378e-02 20 45897908 45898004 97 + 0.807 1.061 0.957
ENSG00000064601 E065 394.8514308 1.398571e-04 2.440863e-03 2.958228e-02 20 45898005 45898109 105 + 2.561 2.609 0.159
ENSG00000064601 E066 3.0649230 1.302487e-01 6.933445e-01 8.747127e-01 20 45898110 45898366 257 + 0.645 0.572 -0.322
ENSG00000064601 E067 488.0202965 1.182184e-03 2.824962e-02 1.572048e-01 20 45898367 45898949 583 + 2.657 2.698 0.138

Help

Please Click HERE to learn more details about the results from DEXseq.