ENSG00000064666

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263097 ENSG00000064666 No_inf pgKDN_inf CNN2 protein_coding protein_coding 146.2392 163.1749 138.4129 9.016781 3.343046 -0.237425 121.098 124.8993 123.8138 1.81971 2.507879 -0.01259215 0.834575 0.771775 0.895375 0.1236 0.03960518 0.0116597 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000064666 E001 1.8506256 0.0191617780 7.498221e-01 9.014220e-01 19 1026586 1026607 22 + 0.421 0.474 0.276
ENSG00000064666 E002 1.7241185 0.0189190938 9.213561e-01 9.754609e-01 19 1026608 1026609 2 + 0.421 0.441 0.106
ENSG00000064666 E003 2.9568983 0.0048353844 8.053135e-01 9.279037e-01 19 1026610 1026617 8 + 0.571 0.611 0.177
ENSG00000064666 E004 9.3142502 0.0137421574 3.691311e-01 6.574439e-01 19 1026618 1026628 11 + 1.055 0.971 -0.309
ENSG00000064666 E005 10.5646849 0.0137742468 7.079146e-01 8.815247e-01 19 1026629 1026630 2 + 1.075 1.046 -0.107
ENSG00000064666 E006 30.1384888 0.0006819615 8.730337e-01 9.566407e-01 19 1026631 1026661 31 + 1.479 1.496 0.058
ENSG00000064666 E007 42.4612352 0.0008026350 7.946721e-01 9.218007e-01 19 1026662 1026690 29 + 1.622 1.642 0.070
ENSG00000064666 E008 55.4632795 0.0002819466 8.709227e-01 9.556169e-01 19 1026691 1026724 34 + 1.746 1.748 0.006
ENSG00000064666 E009 0.2457744 0.0165914052 8.557772e-01   19 1026977 1027074 98 + 0.105 0.086 -0.309
ENSG00000064666 E010 1.3781716 0.0096987742 7.125591e-02 2.705151e-01 19 1030943 1031070 128 + 0.189 0.474 1.861
ENSG00000064666 E011 92.6314696 0.0014440669 3.499275e-01 6.401699e-01 19 1031071 1031192 122 + 1.980 1.957 -0.079
ENSG00000064666 E012 85.8837716 0.0001845486 5.773921e-02 2.404158e-01 19 1032392 1032458 67 + 1.964 1.911 -0.177
ENSG00000064666 E013 103.0731432 0.0026264630 9.609240e-02 3.228478e-01 19 1032559 1032663 105 + 2.041 1.990 -0.171
ENSG00000064666 E014 43.6875686 0.0005755887 2.173004e-01 5.036692e-01 19 1032664 1032669 6 + 1.672 1.625 -0.163
ENSG00000064666 E015 60.2587994 0.0020374154 8.327342e-01 9.396922e-01 19 1032670 1032696 27 + 1.783 1.782 -0.001
ENSG00000064666 E016 5.0974019 0.0378801397 9.153082e-02 3.141443e-01 19 1032697 1032921 225 + 0.630 0.868 0.964
ENSG00000064666 E017 2.1166944 0.0069958343 2.170456e-01 5.032951e-01 19 1036067 1036129 63 + 0.373 0.561 0.954
ENSG00000064666 E018 150.0570875 0.0010972586 9.635239e-01 9.923262e-01 19 1036130 1036246 117 + 2.171 2.178 0.024
ENSG00000064666 E019 163.6894268 0.0001053628 9.745433e-02 3.252739e-01 19 1036416 1036562 147 + 2.229 2.199 -0.098
ENSG00000064666 E020 9.8138423 0.0013978197 5.555863e-01 7.980163e-01 19 1036563 1036688 126 + 1.055 1.010 -0.164
ENSG00000064666 E021 2.3682962 0.0826475827 1.697371e-01 4.417887e-01 19 1036799 1036878 80 + 0.373 0.611 1.176
ENSG00000064666 E022 5.2456951 0.0082435750 8.067594e-03 6.950019e-02 19 1036879 1037000 122 + 0.571 0.905 1.369
ENSG00000064666 E023 9.4277705 0.0015236601 1.122793e-08 7.915908e-07 19 1037001 1037549 549 + 0.571 1.185 2.392
ENSG00000064666 E024 1.8650979 0.1604456586 2.789427e-01 5.721749e-01 19 1037550 1037624 75 + 0.320 0.534 1.152
ENSG00000064666 E025 759.8702537 0.0027953517 1.951650e-01 4.754744e-01 19 1037625 1039068 1444 + 2.861 2.889 0.093

Help

Please Click HERE to learn more details about the results from DEXseq.