ENSG00000064961

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000333651 ENSG00000064961 No_inf pgKDN_inf HMG20B protein_coding protein_coding 88.04372 108.9919 71.45099 3.026692 0.8624455 -0.6091255 54.15343 58.85196 51.663476 0.9393790 1.213205 -0.1879116 0.6283667 0.541800 0.722825 0.181025 0.0007423052 0.0007423052 FALSE TRUE
ENST00000470356 ENSG00000064961 No_inf pgKDN_inf HMG20B protein_coding retained_intron 88.04372 108.9919 71.45099 3.026692 0.8624455 -0.6091255 11.81045 16.41012 7.491089 0.5003455 1.238726 -1.1302931 0.1308250 0.150875 0.104725 -0.046150 0.5947179497 0.0007423052 FALSE FALSE
ENST00000488973 ENSG00000064961 No_inf pgKDN_inf HMG20B protein_coding retained_intron 88.04372 108.9919 71.45099 3.026692 0.8624455 -0.6091255 10.10706 15.92315 5.089229 0.8124578 1.165815 -1.6436806 0.1098417 0.146175 0.071675 -0.074500 0.2340541455 0.0007423052 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000064961 E001 0.3814089 0.4959730524 4.932380e-01   19 3572777 3572822 46 + 0.000 0.195 10.535
ENSG00000064961 E002 0.3814089 0.4959730524 4.932380e-01   19 3572823 3572824 2 + 0.000 0.195 12.216
ENSG00000064961 E003 0.1271363 0.0122641292 1.000000e+00   19 3572825 3572943 119 + 0.000 0.075 11.701
ENSG00000064961 E004 0.0000000       19 3572944 3572947 4 +      
ENSG00000064961 E005 0.0000000       19 3572948 3572976 29 +      
ENSG00000064961 E006 0.0000000       19 3572977 3572978 2 +      
ENSG00000064961 E007 0.0000000       19 3572979 3572985 7 +      
ENSG00000064961 E008 0.0000000       19 3572986 3572994 9 +      
ENSG00000064961 E009 4.4650997 0.0279031965 6.799604e-01 0.8677737037 19 3572995 3573291 297 + 0.682 0.742 0.248
ENSG00000064961 E010 1.6068575 0.1304165311 8.515396e-01 0.9474745986 19 3573292 3573347 56 + 0.413 0.400 -0.074
ENSG00000064961 E011 0.0000000       19 3573692 3573696 5 +      
ENSG00000064961 E012 0.0000000       19 3573697 3573800 104 +      
ENSG00000064961 E013 6.2085687 0.0053607026 4.626572e-01 0.7329898734 19 3573801 3573902 102 + 0.784 0.870 0.336
ENSG00000064961 E014 42.6876125 0.0058375522 4.127394e-06 0.0001592324 19 3573903 3574292 390 + 1.427 1.701 0.936
ENSG00000064961 E015 4.5090314 0.0031328191 2.238261e-02 0.1360732695 19 3574293 3574340 48 + 0.508 0.811 1.299
ENSG00000064961 E016 7.4965522 0.0020574554 2.319085e-02 0.1389750198 19 3574341 3574369 29 + 0.736 0.986 0.964
ENSG00000064961 E017 8.8551858 0.0038373675 3.864858e-02 0.1901717631 19 3574370 3574382 13 + 0.827 1.041 0.806
ENSG00000064961 E018 78.2221637 0.0002194014 7.354520e-01 0.8951118761 19 3574383 3574586 204 + 1.886 1.877 -0.031
ENSG00000064961 E019 0.6244167 0.0150254378 4.238884e-01 0.7031431582 19 3575502 3575539 38 + 0.120 0.244 1.248
ENSG00000064961 E020 29.2362434 0.0015954334 2.918435e-01 0.5852278048 19 3575540 3575541 2 + 1.498 1.441 -0.197
ENSG00000064961 E021 80.6268164 0.0002086495 3.319552e-01 0.6241256907 19 3575542 3575650 109 + 1.912 1.882 -0.100
ENSG00000064961 E022 40.6898536 0.0003483900 8.050697e-01 0.9278606989 19 3575651 3575660 10 + 1.592 1.607 0.049
ENSG00000064961 E023 2.2507807 0.1150980439 2.658260e-01 0.5592859334 19 3575661 3575875 215 + 0.356 0.561 1.055
ENSG00000064961 E024 4.4953444 0.0031554380 5.676324e-02 0.2378720297 19 3575876 3576260 385 + 0.549 0.798 1.055
ENSG00000064961 E025 55.4794623 0.0005126277 8.177665e-01 0.9336580027 19 3576261 3576307 47 + 1.738 1.731 -0.024
ENSG00000064961 E026 1.3878336 0.0108432096 3.568312e-02 0.1810814465 19 3576308 3576351 44 + 0.120 0.460 2.570
ENSG00000064961 E027 1.7682981 0.0077582274 9.754029e-03 0.0790494097 19 3576352 3576552 201 + 0.120 0.538 2.948
ENSG00000064961 E028 62.5454920 0.0002421455 9.139195e-01 0.9728870944 19 3576553 3576615 63 + 1.786 1.784 -0.006
ENSG00000064961 E029 38.8666566 0.0003699367 2.884330e-01 0.5820095640 19 3576616 3576625 10 + 1.613 1.564 -0.167
ENSG00000064961 E030 0.1268540 0.0123411963 1.000000e+00   19 3576885 3576891 7 + 0.000 0.075 11.701
ENSG00000064961 E031 115.7390585 0.0001892985 3.884524e-01 0.6742876895 19 3576892 3577107 216 + 2.062 2.041 -0.071
ENSG00000064961 E032 63.8760139 0.0002400145 1.006258e-01 0.3311909140 19 3577981 3578113 133 + 1.831 1.772 -0.199
ENSG00000064961 E033 4.2109770 0.0033609061 8.263150e-01 0.9370973424 19 3578114 3578444 331 + 0.682 0.712 0.122
ENSG00000064961 E034 92.4035404 0.0022990463 1.216379e-01 0.3692473485 19 3578509 3578701 193 + 1.985 1.932 -0.178
ENSG00000064961 E035 105.8916832 0.0001624268 6.641364e-01 0.8603225825 19 3578702 3579088 387 + 2.017 2.007 -0.034

Help

Please Click HERE to learn more details about the results from DEXseq.