ENSG00000065057

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000219066 ENSG00000065057 No_inf pgKDN_inf NTHL1 protein_coding protein_coding 14.50771 27.08933 9.625901 1.129015 0.8385732 -1.491766 6.4584529 15.609490 2.0959199 2.0309858 2.0959199 -2.890825 0.34893333 0.573600 0.198125 -0.375475 0.056166260 0.004433687 FALSE TRUE
ENST00000561862 ENSG00000065057 No_inf pgKDN_inf NTHL1 protein_coding retained_intron 14.50771 27.08933 9.625901 1.129015 0.8385732 -1.491766 0.9601476 2.880443 0.0000000 0.5354726 0.0000000 -8.175147 0.03590000 0.107700 0.000000 -0.107700 0.004433687 0.004433687 FALSE TRUE
ENST00000562951 ENSG00000065057 No_inf pgKDN_inf NTHL1 protein_coding protein_coding_CDS_not_defined 14.50771 27.08933 9.625901 1.129015 0.8385732 -1.491766 0.9072382 0.000000 1.9937819 0.0000000 1.9937819 7.646582 0.09253333 0.000000 0.173375 0.173375 0.750735830 0.004433687 FALSE FALSE
ENST00000565406 ENSG00000065057 No_inf pgKDN_inf NTHL1 protein_coding retained_intron 14.50771 27.08933 9.625901 1.129015 0.8385732 -1.491766 1.4679987 3.728217 0.0000000 1.2481910 0.0000000 -8.546207 0.07722500 0.139725 0.000000 -0.139725 0.113306660 0.004433687 FALSE TRUE
ENST00000623977 ENSG00000065057 No_inf pgKDN_inf NTHL1 protein_coding retained_intron 14.50771 27.08933 9.625901 1.129015 0.8385732 -1.491766 1.1594999 2.970550 0.2291218 0.3773463 0.1464054 -3.639761 0.05985000 0.108725 0.027775 -0.080950 0.285697802 0.004433687 FALSE TRUE
ENST00000651570 ENSG00000065057 No_inf pgKDN_inf NTHL1 protein_coding protein_coding 14.50771 27.08933 9.625901 1.129015 0.8385732 -1.491766 2.3515808 0.000000 4.3316288 0.0000000 2.0106848 8.762093 0.29927500 0.000000 0.511750 0.511750 0.044054550 0.004433687 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000065057 E001 0.0000000       16 2039815 2039817 3 -      
ENSG00000065057 E002 0.0000000       16 2039818 2039819 2 -      
ENSG00000065057 E003 0.0000000       16 2039820 2039820 1 -      
ENSG00000065057 E004 0.0000000       16 2039821 2039822 2 -      
ENSG00000065057 E005 0.8883216 0.0829405212 0.159857938 0.42737378 16 2039823 2039851 29 - 0.000 0.290 10.906
ENSG00000065057 E006 12.2569888 0.0015875887 0.547107548 0.79262110 16 2039852 2040047 196 - 0.993 1.064 0.260
ENSG00000065057 E007 13.3437172 0.0011703520 0.525134609 0.77798682 16 2040133 2040238 106 - 1.111 1.074 -0.136
ENSG00000065057 E008 0.6257372 0.0161887587 1.000000000 1.00000000 16 2040239 2040241 3 - 0.159 0.188 0.297
ENSG00000065057 E009 1.5225236 0.0090037349 0.029825035 0.16246676 16 2040242 2040468 227 - 0.000 0.420 12.647
ENSG00000065057 E010 0.6348960 0.0144493073 0.292250106 0.58567299 16 2042002 2042146 145 - 0.000 0.225 11.464
ENSG00000065057 E011 0.4998298 0.0223264662 0.941820892   16 2043484 2043566 83 - 0.159 0.148 -0.118
ENSG00000065057 E012 17.4319058 0.0008854724 0.125479656 0.37548524 16 2043567 2043726 160 - 1.261 1.167 -0.331
ENSG00000065057 E013 0.0000000       16 2043727 2043803 77 -      
ENSG00000065057 E014 0.0000000       16 2044050 2044079 30 -      
ENSG00000065057 E015 17.4768622 0.0008850156 0.813558420 0.93179995 16 2044630 2044800 171 - 1.192 1.191 -0.006
ENSG00000065057 E016 1.2589663 0.0397139253 0.311203517 0.60440945 16 2044801 2044826 26 - 0.159 0.346 1.466
ENSG00000065057 E017 12.5628759 0.0012092160 0.142288123 0.40128465 16 2046128 2046279 152 - 1.140 1.032 -0.391
ENSG00000065057 E018 6.6018703 0.0033577081 0.526145276 0.77862522 16 2046280 2046366 87 - 0.856 0.799 -0.225
ENSG00000065057 E019 5.8123422 0.0026164366 0.002397936 0.02920078 16 2046937 2047708 772 - 0.366 0.835 2.138
ENSG00000065057 E020 8.2592420 0.0019843299 0.529263819 0.78060913 16 2047709 2047866 158 - 0.829 0.913 0.324

Help

Please Click HERE to learn more details about the results from DEXseq.