ENSG00000066739

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261834 ENSG00000066739 No_inf pgKDN_inf ATG2B protein_coding protein_coding_CDS_not_defined 6.414134 11.18745 3.899058 2.61887 0.1447055 -1.518278 0.4812732 0.1119741 0.9436000 0.11197410 0.15694305 2.9668094 0.11156667 0.010550 0.243500 0.232950 0.01089798 0.01089798 FALSE TRUE
ENST00000359933 ENSG00000066739 No_inf pgKDN_inf ATG2B protein_coding protein_coding 6.414134 11.18745 3.899058 2.61887 0.1447055 -1.518278 2.5510909 3.2084037 2.2154634 0.05604025 0.06974476 -0.5322395 0.51692500 0.375525 0.572450 0.196925 0.61768702 0.01089798 FALSE TRUE
ENST00000553643 ENSG00000066739 No_inf pgKDN_inf ATG2B protein_coding retained_intron 6.414134 11.18745 3.899058 2.61887 0.1447055 -1.518278 0.2382524 0.2981746 0.4165828 0.29817456 0.24808675 0.4690780 0.04339167 0.028125 0.102050 0.073925 0.70111241 0.01089798   FALSE
ENST00000554151 ENSG00000066739 No_inf pgKDN_inf ATG2B protein_coding protein_coding_CDS_not_defined 6.414134 11.18745 3.899058 2.61887 0.1447055 -1.518278 0.4972641 0.7994039 0.3234114 0.50832635 0.32341135 -1.2795566 0.06435000 0.055450 0.081975 0.026525 0.96013600 0.01089798   FALSE
ENST00000555263 ENSG00000066739 No_inf pgKDN_inf ATG2B protein_coding retained_intron 6.414134 11.18745 3.899058 2.61887 0.1447055 -1.518278 0.4179091 0.4436821 0.0000000 0.25771750 0.00000000 -5.5036097 0.07202500 0.076575 0.000000 -0.076575 0.82764468 0.01089798 FALSE FALSE
MSTRG.9038.6 ENSG00000066739 No_inf pgKDN_inf ATG2B protein_coding   6.414134 11.18745 3.899058 2.61887 0.1447055 -1.518278 2.1086042 6.3258125 0.0000000 2.55439997 0.00000000 -9.3073858 0.15125000 0.453750 0.000000 -0.453750 0.02236985 0.01089798   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000066739 E001 125.2203714 0.0001705941 1.535192e-06 6.748089e-05 14 96279195 96285985 6791 - 2.027 2.121 0.314
ENSG00000066739 E002 0.3706473 0.0168540801 8.865454e-01   14 96289456 96289655 200 - 0.115 0.145 0.384
ENSG00000066739 E003 3.6813796 0.0125631308 4.424111e-01 7.177411e-01 14 96289656 96289805 150 - 0.719 0.619 -0.423
ENSG00000066739 E004 0.1265070 0.0122746487 8.380345e-01   14 96290136 96290213 78 - 0.000 0.078 10.751
ENSG00000066739 E005 3.3365087 0.0045797197 7.892149e-01 9.191233e-01 14 96290436 96290569 134 - 0.605 0.640 0.150
ENSG00000066739 E006 1.3869839 0.0098300464 2.399289e-02 1.418807e-01 14 96290570 96290577 8 - 0.115 0.474 2.706
ENSG00000066739 E007 1.7596123 0.0081177738 3.965309e-02 1.930531e-01 14 96290578 96290590 13 - 0.206 0.528 1.969
ENSG00000066739 E008 4.4524520 0.1164262631 8.664908e-01 9.539942e-01 14 96290814 96290935 122 - 0.694 0.744 0.207
ENSG00000066739 E009 2.8604516 0.1498990834 2.645917e-01 5.577315e-01 14 96291600 96291682 83 - 0.450 0.640 0.888
ENSG00000066739 E010 0.4903553 0.0176337206 6.740865e-01   14 96291683 96292028 346 - 0.206 0.145 -0.616
ENSG00000066739 E011 1.9394924 0.0074308242 6.731418e-02 2.616632e-01 14 96292029 96292098 70 - 0.605 0.340 -1.353
ENSG00000066739 E012 0.7525912 0.0150284289 2.342915e-01 5.233139e-01 14 96292982 96293214 233 - 0.115 0.299 1.706
ENSG00000066739 E013 5.3336554 0.0033203575 1.374720e-03 1.914880e-02 14 96294960 96295167 208 - 0.977 0.619 -1.423
ENSG00000066739 E014 2.6058507 0.0208353751 5.784918e-01 8.116444e-01 14 96295482 96295560 79 - 0.494 0.576 0.384
ENSG00000066739 E015 3.4079754 0.0042526814 6.270859e-02 2.516462e-01 14 96302007 96302108 102 - 0.767 0.528 -1.031
ENSG00000066739 E016 5.2810667 0.0101483016 3.727518e-01 6.605887e-01 14 96303061 96303255 195 - 0.849 0.744 -0.414
ENSG00000066739 E017 3.2172080 0.0045972295 6.045632e-01 8.275135e-01 14 96304495 96304603 109 - 0.571 0.640 0.302
ENSG00000066739 E018 4.6270280 0.0514360905 1.148189e-01 3.571886e-01 14 96305589 96305815 227 - 0.867 0.640 -0.920
ENSG00000066739 E019 3.6645123 0.0038931492 1.299820e-01 3.824160e-01 14 96306714 96306916 203 - 0.767 0.576 -0.808
ENSG00000066739 E020 3.3210210 0.0072827411 6.096636e-01 8.301746e-01 14 96309453 96309594 142 - 0.666 0.598 -0.294
ENSG00000066739 E021 3.3040001 0.1677392694 3.943326e-01 6.791178e-01 14 96311117 96311287 171 - 0.720 0.553 -0.724
ENSG00000066739 E022 1.9816632 0.0106385185 4.932816e-01 7.552132e-01 14 96311542 96311618 77 - 0.401 0.502 0.522
ENSG00000066739 E023 1.8283383 0.0383731030 3.157326e-01 6.085381e-01 14 96312089 96312159 71 - 0.534 0.377 -0.808
ENSG00000066739 E024 2.8083260 0.0052464165 2.258780e-01 5.137695e-01 14 96313065 96313157 93 - 0.666 0.502 -0.741
ENSG00000066739 E025 3.0636707 0.0048401430 3.960868e-01 6.808996e-01 14 96313329 96313435 107 - 0.666 0.553 -0.500
ENSG00000066739 E026 2.6877315 0.0083772217 1.621804e-01 4.306553e-01 14 96315154 96315234 81 - 0.666 0.474 -0.879
ENSG00000066739 E027 3.5380266 0.0111048837 9.933884e-02 3.291675e-01 14 96315384 96315583 200 - 0.767 0.553 -0.915
ENSG00000066739 E028 1.3355555 0.1731153457 1.786646e-01 4.535643e-01 14 96316533 96316565 33 - 0.494 0.253 -1.424
ENSG00000066739 E029 3.0602382 0.0048553203 2.121812e-01 4.974044e-01 14 96316566 96316679 114 - 0.694 0.528 -0.731
ENSG00000066739 E030 0.9717784 0.1701012524 2.783805e-01 5.716875e-01 14 96316680 96316683 4 - 0.401 0.202 -1.353
ENSG00000066739 E031 0.9901876 0.0630222715 9.100627e-01 9.715045e-01 14 96317145 96317147 3 - 0.281 0.299 0.121
ENSG00000066739 E032 2.6136313 0.0867927997 3.973351e-01 6.814884e-01 14 96317148 96317317 170 - 0.450 0.598 0.706
ENSG00000066739 E033 0.3808443 0.0194984606 2.155774e-01   14 96317698 96317708 11 - 0.000 0.202 12.224
ENSG00000066739 E034 0.2356421 0.0156315855 1.279550e-01   14 96317709 96317722 14 - 0.206 0.000 -13.683
ENSG00000066739 E035 1.8327760 0.0650167763 3.255549e-01 6.180822e-01 14 96317723 96317855 133 - 0.534 0.377 -0.808
ENSG00000066739 E036 0.1265070 0.0122746487 8.380345e-01   14 96318234 96318298 65 - 0.000 0.078 10.751
ENSG00000066739 E037 1.7137906 0.0098292892 4.363548e-01 7.128054e-01 14 96322112 96322254 143 - 0.494 0.377 -0.616
ENSG00000066739 E038 0.0000000       14 96322255 96322435 181 -      
ENSG00000066739 E039 1.4779249 0.0095173924 8.834912e-01 9.608447e-01 14 96322540 96322735 196 - 0.401 0.377 -0.130
ENSG00000066739 E040 1.3596026 0.0268046616 8.287042e-01 9.380473e-01 14 96323896 96323998 103 - 0.345 0.377 0.192
ENSG00000066739 E041 0.0000000       14 96324098 96324178 81 -      
ENSG00000066739 E042 2.4402912 0.0061069759 1.682267e-01 4.393758e-01 14 96325649 96325922 274 - 0.637 0.444 -0.905
ENSG00000066739 E043 2.9370995 0.0048565561 3.052462e-01 5.985946e-01 14 96328347 96328535 189 - 0.666 0.528 -0.616
ENSG00000066739 E044 1.6094407 0.2190090047 6.178934e-01 8.345971e-01 14 96328674 96328766 93 - 0.344 0.444 0.555
ENSG00000066739 E045 1.8318008 0.0087841172 2.872721e-01 5.806385e-01 14 96329484 96329634 151 - 0.535 0.377 -0.809
ENSG00000066739 E046 3.0847224 0.0045990677 9.642759e-01 9.924532e-01 14 96331376 96331637 262 - 0.605 0.598 -0.031
ENSG00000066739 E047 1.1223910 0.0109393658 2.717005e-01 5.654600e-01 14 96332305 96332410 106 - 0.206 0.377 1.192
ENSG00000066739 E048 1.0978356 0.0835867535 3.739821e-01 6.616917e-01 14 96332501 96332655 155 - 0.401 0.253 -0.938
ENSG00000066739 E049 2.0953603 0.0069756159 8.943808e-01 9.650298e-01 14 96333688 96333873 186 - 0.494 0.474 -0.101
ENSG00000066739 E050 0.9879478 0.0122040361 9.047254e-01 9.694912e-01 14 96334405 96334501 97 - 0.281 0.299 0.121
ENSG00000066739 E051 2.0952940 0.0072548606 8.930577e-01 9.645186e-01 14 96341522 96341701 180 - 0.494 0.474 -0.101
ENSG00000066739 E052 1.8690302 0.0073501907 2.984592e-01 5.914572e-01 14 96343119 96343281 163 - 0.345 0.502 0.844
ENSG00000066739 E053 0.6173681 0.0158977824 9.851541e-01 9.989951e-01 14 96344654 96344756 103 - 0.206 0.202 -0.031
ENSG00000066739 E054 0.4993265 0.0157542874 5.642866e-01   14 96345233 96345385 153 - 0.115 0.202 0.969
ENSG00000066739 E055 0.4814789 0.0159328859 1.564730e-01   14 96347179 96347341 163 - 0.281 0.078 -2.201
ENSG00000066739 E056 1.7153958 0.0080409907 4.336656e-01 7.110618e-01 14 96362815 96363341 527 - 0.494 0.377 -0.616

Help

Please Click HERE to learn more details about the results from DEXseq.