ENSG00000066855

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262146 ENSG00000066855 No_inf pgKDN_inf MTFR1 protein_coding protein_coding 20.71616 23.98743 20.36538 2.987507 1.594182 -0.2360527 11.023438 8.061659 14.1909694 0.3532888 0.7170508 0.8150524 0.55687500 0.350350 0.709525 0.359175 0.00980192 0.00980192 FALSE TRUE
ENST00000518352 ENSG00000066855 No_inf pgKDN_inf MTFR1 protein_coding retained_intron 20.71616 23.98743 20.36538 2.987507 1.594182 -0.2360527 3.576415 5.264802 2.3274762 1.3548932 1.0356299 -1.1741652 0.16194167 0.211250 0.104575 -0.106675 0.57102154 0.00980192   FALSE
ENST00000520398 ENSG00000066855 No_inf pgKDN_inf MTFR1 protein_coding protein_coding_CDS_not_defined 20.71616 23.98743 20.36538 2.987507 1.594182 -0.2360527 1.850287 2.886958 0.9838871 0.7258369 0.3292875 -1.5433847 0.08763333 0.122250 0.044975 -0.077275 0.50073652 0.00980192   FALSE
ENST00000527553 ENSG00000066855 No_inf pgKDN_inf MTFR1 protein_coding protein_coding_CDS_not_defined 20.71616 23.98743 20.36538 2.987507 1.594182 -0.2360527 3.327433 6.968000 1.8974602 1.3097771 0.8133390 -1.8711607 0.14846667 0.284925 0.095925 -0.189000 0.27703453 0.00980192   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000066855 E001 0.4746825 0.023580005 9.973772e-02   8 65644734 65644738 5 + 0.259 0.000 -11.351
ENSG00000066855 E002 3.0149801 0.004641794 1.710939e-01 4.434652e-01 8 65644739 65644784 46 + 0.669 0.485 -0.836
ENSG00000066855 E003 0.0000000       8 65669871 65669872 2 +      
ENSG00000066855 E004 8.0087570 0.001924916 4.150826e-01 6.952350e-01 8 65669873 65669980 108 + 0.981 0.906 -0.281
ENSG00000066855 E005 4.8407673 0.003099950 2.571441e-01 5.494523e-01 8 65669981 65670018 38 + 0.813 0.683 -0.528
ENSG00000066855 E006 0.0000000       8 65679503 65679650 148 +      
ENSG00000066855 E007 0.0000000       8 65682044 65682080 37 +      
ENSG00000066855 E008 0.1268540 0.012317357 3.744140e-01   8 65682328 65682352 25 + 0.000 0.112 11.735
ENSG00000066855 E009 8.1467870 0.002080344 2.822598e-04 5.523731e-03 8 65682353 65682451 99 + 1.080 0.709 -1.421
ENSG00000066855 E010 0.0000000       8 65689566 65689599 34 +      
ENSG00000066855 E011 10.6138607 0.011986541 3.446386e-02 1.773141e-01 8 65693644 65693759 116 + 1.135 0.936 -0.728
ENSG00000066855 E012 16.5630363 0.001469413 8.722057e-01 9.563232e-01 8 65704694 65704929 236 + 1.233 1.249 0.055
ENSG00000066855 E013 4.6470232 0.003179051 4.463556e-01 7.207276e-01 8 65707010 65707044 35 + 0.706 0.798 0.374
ENSG00000066855 E014 3.0514265 0.005043857 7.815966e-01 9.160330e-01 8 65707045 65707052 8 + 0.586 0.626 0.178
ENSG00000066855 E015 10.0717191 0.034328751 5.572021e-01 7.992522e-01 8 65707053 65707220 168 + 1.065 1.005 -0.221
ENSG00000066855 E016 5.5878647 0.043958281 6.922131e-01 8.740235e-01 8 65707221 65707256 36 + 0.840 0.778 -0.245
ENSG00000066855 E017 5.3165297 0.019353829 1.472018e-01 4.083941e-01 8 65707843 65707856 14 + 0.865 0.683 -0.728
ENSG00000066855 E018 6.9151040 0.003696821 3.488389e-01 6.393946e-01 8 65707857 65707889 33 + 0.932 0.837 -0.361
ENSG00000066855 E019 11.0312859 0.001283385 2.280379e-01 5.164825e-01 8 65707890 65708011 122 + 1.115 1.017 -0.356
ENSG00000066855 E020 0.0000000       8 65708012 65708338 327 +      
ENSG00000066855 E021 88.6988116 0.008271890 9.246616e-01 9.771507e-01 8 65708976 65710562 1587 + 1.947 1.950 0.010
ENSG00000066855 E022 0.0000000       8 65719380 65719481 102 +      
ENSG00000066855 E023 3.8866651 0.045127928 2.432506e-05 7.286826e-04 8 65719482 65719748 267 + 0.305 0.936 2.904
ENSG00000066855 E024 5.4758639 0.002722950 2.384389e-05 7.160336e-04 8 65720404 65720596 193 + 0.538 1.017 1.941
ENSG00000066855 E025 0.6171781 0.015996270 4.020382e-01 6.851685e-01 8 65725316 65725350 35 + 0.149 0.274 1.111
ENSG00000066855 E026 1.2410875 0.404616327 1.815188e-01 4.574784e-01 8 65725351 65725513 163 + 0.207 0.485 1.749
ENSG00000066855 E027 0.8617241 0.012932624 4.016995e-01 6.847846e-01 8 65725514 65725600 87 + 0.207 0.337 0.941
ENSG00000066855 E028 5.7742966 0.002586125 1.039659e-09 8.830388e-08 8 65728361 65728603 243 + 0.385 1.095 3.004
ENSG00000066855 E029 0.1176306 0.011822949 7.673919e-01   8 65770947 65771261 315 + 0.081 0.000 -11.874

Help

Please Click HERE to learn more details about the results from DEXseq.