ENSG00000067182

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000162749 ENSG00000067182 No_inf pgKDN_inf TNFRSF1A protein_coding protein_coding 55.11634 55.04004 58.46523 1.282561 1.553452 0.087082 46.020138 37.91092 55.5274125 1.978574 1.0584381 0.5504659 0.833200 0.688525 0.951725 0.263200 0.0000165073 1.65073e-05 FALSE TRUE
ENST00000534885 ENSG00000067182 No_inf pgKDN_inf TNFRSF1A protein_coding nonsense_mediated_decay 55.11634 55.04004 58.46523 1.282561 1.553452 0.087082 5.418071 11.55932 0.8714877 1.750906 0.8714877 -3.7142193 0.099825 0.210825 0.014000 -0.196825 0.0025054774 1.65073e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000067182 E001 0.1265070 0.0122882931 0.563260005   12 6328757 6328770 14 - 0.000 0.093 9.326
ENSG00000067182 E002 1.2405836 0.0187321356 0.236365711 0.52543134 12 6328771 6328775 5 - 0.243 0.427 1.156
ENSG00000067182 E003 4.9478017 0.0051760008 0.083885121 0.29880854 12 6328776 6328790 15 - 0.654 0.858 0.827
ENSG00000067182 E004 105.1479779 0.0023876400 0.488722129 0.75193251 12 6328791 6329144 354 - 2.013 2.036 0.078
ENSG00000067182 E005 49.4337217 0.0003195857 0.696830167 0.87625170 12 6329145 6329236 92 - 1.693 1.710 0.055
ENSG00000067182 E006 134.5473052 0.0005907681 0.780123335 0.91525707 12 6329237 6329622 386 - 2.135 2.128 -0.024
ENSG00000067182 E007 43.1410136 0.0109239223 0.869002534 0.95488830 12 6329778 6329867 90 - 1.649 1.639 -0.034
ENSG00000067182 E008 27.8322512 0.0005309698 0.988411167 1.00000000 12 6329868 6329899 32 - 1.459 1.459 -0.003
ENSG00000067182 E009 49.4343321 0.0003288570 0.098413303 0.32727976 12 6329900 6329993 94 - 1.664 1.733 0.236
ENSG00000067182 E010 51.5067926 0.0027064324 0.158692668 0.42575389 12 6329994 6330066 73 - 1.684 1.748 0.217
ENSG00000067182 E011 0.8518064 0.2034896471 0.731814683 0.89338373 12 6330067 6330266 200 - 0.301 0.235 -0.482
ENSG00000067182 E012 37.0336065 0.0006593210 0.771352390 0.91184122 12 6330267 6330295 29 - 1.572 1.586 0.048
ENSG00000067182 E013 0.0000000       12 6330442 6330597 156 -      
ENSG00000067182 E014 63.4695121 0.0002762789 0.932201967 0.98027610 12 6330598 6330711 114 - 1.810 1.807 -0.011
ENSG00000067182 E015 0.4736100 0.0158989057 0.040496509   12 6330712 6330852 141 - 0.301 0.000 -13.775
ENSG00000067182 E016 46.3177280 0.0003769058 0.971228108 0.99444170 12 6330853 6330926 74 - 1.675 1.674 -0.005
ENSG00000067182 E017 0.4894115 0.0158420532 0.963597829   12 6330927 6330960 34 - 0.176 0.170 -0.066
ENSG00000067182 E018 2.5106283 0.0070593724 0.001657431 0.02208843 12 6330961 6331875 915 - 0.243 0.705 2.436
ENSG00000067182 E019 2.1096507 0.0241086317 0.117998668 0.36280339 12 6331876 6331993 118 - 0.353 0.588 1.197
ENSG00000067182 E020 0.1170040 0.0117100853 0.514130312   12 6333066 6333068 3 - 0.097 0.000 -11.820
ENSG00000067182 E021 44.2723528 0.0003999873 0.073341554 0.27537422 12 6333069 6333147 79 - 1.611 1.691 0.272
ENSG00000067182 E022 3.2461040 0.0046711787 0.007562890 0.06654119 12 6333148 6333366 219 - 0.398 0.762 1.670
ENSG00000067182 E023 55.6069831 0.0002595367 0.375154124 0.66272191 12 6333367 6333451 85 - 1.733 1.768 0.118
ENSG00000067182 E024 28.5473410 0.0004917357 0.876513699 0.95814086 12 6333452 6333457 6 - 1.474 1.466 -0.029
ENSG00000067182 E025 36.2459117 0.0003941337 0.690458017 0.87292927 12 6333458 6333516 59 - 1.581 1.561 -0.066
ENSG00000067182 E026 45.4439979 0.0019368767 0.708734792 0.88195717 12 6333737 6333838 102 - 1.675 1.658 -0.059
ENSG00000067182 E027 22.0918149 0.0012174674 0.120394771 0.36702304 12 6333839 6333844 6 - 1.412 1.314 -0.338
ENSG00000067182 E028 25.9701596 0.0008609507 0.041843219 0.19906255 12 6333845 6333865 21 - 1.489 1.371 -0.407
ENSG00000067182 E029 0.2543986 0.0160331761 0.258492026   12 6333866 6333890 25 - 0.000 0.170 12.248
ENSG00000067182 E030 0.4979743 0.0298726808 0.345656133   12 6333920 6334090 171 - 0.097 0.235 1.519
ENSG00000067182 E031 54.8205420 0.0018965811 0.001799523 0.02354573 12 6334091 6334244 154 - 1.812 1.678 -0.453
ENSG00000067182 E032 47.8455459 0.0003089823 0.021492919 0.13278340 12 6341776 6342114 339 - 1.737 1.639 -0.332

Help

Please Click HERE to learn more details about the results from DEXseq.