ENSG00000067596

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262415 ENSG00000067596 No_inf pgKDN_inf DHX8 protein_coding protein_coding 25.4886 20.95515 27.75645 1.524991 0.6673419 0.4053495 10.5316704 9.9796372 11.360017 0.2113590 0.7392894 0.1867302 0.4234167 0.483425 0.409475 -0.073950 8.169842e-01 6.594888e-08 FALSE TRUE
ENST00000540306 ENSG00000067596 No_inf pgKDN_inf DHX8 protein_coding protein_coding 25.4886 20.95515 27.75645 1.524991 0.6673419 0.4053495 3.9170984 0.0000000 5.123285 0.0000000 0.6287248 9.0037386 0.1422667 0.000000 0.183900 0.183900 6.594888e-08 6.594888e-08 FALSE TRUE
ENST00000587574 ENSG00000067596 No_inf pgKDN_inf DHX8 protein_coding protein_coding 25.4886 20.95515 27.75645 1.524991 0.6673419 0.4053495 9.2494641 9.9000287 8.293046 1.5073681 0.4570518 -0.2552486 0.3660167 0.463975 0.298625 -0.165350 2.875051e-01 6.594888e-08   FALSE
ENST00000650571 ENSG00000067596 No_inf pgKDN_inf DHX8 protein_coding nonsense_mediated_decay 25.4886 20.95515 27.75645 1.524991 0.6673419 0.4053495 0.9707753 0.3088436 2.039577 0.3088436 0.9232769 2.6844053 0.0359000 0.012650 0.074475 0.061825 4.742782e-01 6.594888e-08 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000067596 E001 0.0000000       17 43483865 43483959 95 +      
ENSG00000067596 E002 0.0000000       17 43483960 43483962 3 +      
ENSG00000067596 E003 0.1170040 0.0117593206 0.7208123778   17 43483963 43483974 12 + 0.084 0.000 -8.909
ENSG00000067596 E004 7.5854255 0.0028445646 0.0105825353 0.083383266 17 43483975 43484139 165 + 1.032 0.763 -1.026
ENSG00000067596 E005 6.4216301 0.0537020414 0.4355980618 0.712267843 17 43484140 43484185 46 + 0.915 0.803 -0.430
ENSG00000067596 E006 7.5646674 0.0147925770 0.7283957454 0.891692492 17 43489449 43489534 86 + 0.915 0.949 0.130
ENSG00000067596 E007 6.9568679 0.0026244973 0.6640356958 0.860274824 17 43490391 43490463 73 + 0.880 0.921 0.157
ENSG00000067596 E008 0.0000000       17 43490464 43490493 30 +      
ENSG00000067596 E009 3.6633811 0.0068016737 0.6701804010 0.863007992 17 43491165 43491193 29 + 0.643 0.695 0.218
ENSG00000067596 E010 5.4676473 0.0040678917 0.7141960197 0.884876678 17 43491194 43491250 57 + 0.828 0.784 -0.175
ENSG00000067596 E011 7.5039595 0.0254934834 0.3342258019 0.626110246 17 43492183 43492292 110 + 0.977 0.858 -0.452
ENSG00000067596 E012 22.6345187 0.0388728419 0.1635592433 0.432442974 17 43492681 43493040 360 + 1.433 1.280 -0.532
ENSG00000067596 E013 12.4353564 0.0011788738 0.0084997505 0.071981929 17 43493445 43493589 145 + 1.212 0.989 -0.805
ENSG00000067596 E014 19.7193855 0.0008587927 0.0074762747 0.066026756 17 43493683 43493886 204 + 1.387 1.203 -0.643
ENSG00000067596 E015 9.7875828 0.0014826094 0.0510667636 0.223721455 17 43496181 43496268 88 + 1.103 0.921 -0.671
ENSG00000067596 E016 9.8754881 0.0014984592 0.7566557229 0.904184645 17 43498862 43498959 98 + 1.023 1.048 0.088
ENSG00000067596 E017 14.9708762 0.0009545426 0.7758967626 0.913914171 17 43499956 43500103 148 + 1.212 1.187 -0.087
ENSG00000067596 E018 19.5524206 0.0008020714 0.3531970911 0.642993719 17 43504644 43504825 182 + 1.339 1.274 -0.227
ENSG00000067596 E019 18.1087581 0.0008536366 0.4371776410 0.713528425 17 43507003 43507197 195 + 1.303 1.247 -0.199
ENSG00000067596 E020 18.5428375 0.0019919788 0.7432636399 0.898457043 17 43507503 43507688 186 + 1.280 1.299 0.067
ENSG00000067596 E021 20.1088062 0.0007183960 0.9373758510 0.982087053 17 43507809 43508019 211 + 1.321 1.323 0.005
ENSG00000067596 E022 18.9169500 0.0007958304 0.5411220156 0.788801719 17 43508339 43508520 182 + 1.280 1.317 0.130
ENSG00000067596 E023 21.1374047 0.0008275398 0.4089976172 0.691240834 17 43513362 43513502 141 + 1.367 1.311 -0.195
ENSG00000067596 E024 25.9800983 0.0063493532 0.2396127230 0.528687311 17 43517167 43517322 156 + 1.463 1.383 -0.277
ENSG00000067596 E025 1.7342734 0.0652272465 0.1412046742 0.399791906 17 43517323 43520129 2807 + 0.314 0.549 1.258
ENSG00000067596 E026 21.3586955 0.0049631218 0.5449165664 0.791082024 17 43520130 43520267 138 + 1.330 1.367 0.129
ENSG00000067596 E027 21.9293873 0.0006230026 0.9892390754 1.000000000 17 43520751 43520879 129 + 1.359 1.357 -0.009
ENSG00000067596 E028 35.9470991 0.0024016943 0.8224848440 0.935571156 17 43521369 43521565 197 + 1.562 1.570 0.027
ENSG00000067596 E029 26.9510291 0.0006705036 0.6248141239 0.838580310 17 43522047 43522151 105 + 1.433 1.457 0.082
ENSG00000067596 E030 19.4906820 0.0007454499 0.9529395585 0.988400587 17 43522152 43522226 75 + 1.312 1.305 -0.026
ENSG00000067596 E031 77.1589313 0.0002240940 0.1278345379 0.379059488 17 43523628 43524185 558 + 1.869 1.915 0.154
ENSG00000067596 E032 82.1341851 0.0001893740 0.0002502884 0.005029454 17 43524186 43526386 2201 + 1.864 1.975 0.372
ENSG00000067596 E033 8.9616390 0.0019019887 0.0691309001 0.265676640 17 43526387 43526495 109 + 0.915 1.079 0.608
ENSG00000067596 E034 11.0079823 0.0012745339 0.2419203256 0.531555564 17 43526496 43526803 308 + 1.032 1.128 0.346
ENSG00000067596 E035 0.0000000       17 43536412 43536498 87 +      
ENSG00000067596 E036 0.9788541 0.0119577782 0.6828234206 0.868591202 17 43544162 43544784 623 + 0.267 0.328 0.410
ENSG00000067596 E037 0.0000000       17 43544785 43544815 31 +      
ENSG00000067596 E038 0.0000000       17 43590088 43590165 78 +      
ENSG00000067596 E039 0.0000000       17 43590166 43590741 576 +      
ENSG00000067596 E040 0.0000000       17 43609887 43610338 452 +      

Help

Please Click HERE to learn more details about the results from DEXseq.