ENSG00000067704

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000366922 ENSG00000067704 No_inf pgKDN_inf IARS2 protein_coding protein_coding 89.26949 67.45931 100.6522 2.747342 0.945133 0.5772183 83.360229 58.100418 100.2909093 1.076491 1.0058770 0.7874659 0.92975833 0.865825 0.996425 0.1306 0.002818118 0.002818118 FALSE TRUE
ENST00000467924 ENSG00000067704 No_inf pgKDN_inf IARS2 protein_coding protein_coding_CDS_not_defined 89.26949 67.45931 100.6522 2.747342 0.945133 0.5772183 5.536003 8.461806 0.3612666 3.468789 0.3612666 -4.5121420 0.06504167 0.120575 0.003575 -0.1170 0.092476457 0.002818118 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000067704 E001 44.7506704 0.0072910575 1.127269e-03 0.0164363745 1 220094132 220094483 352 + 1.724 1.531 -0.658
ENSG00000067704 E002 29.8713365 0.0004794173 2.119798e-02 0.1317013185 1 220096104 220096226 123 + 1.533 1.401 -0.454
ENSG00000067704 E003 41.6079630 0.0174758370 6.138358e-02 0.2488062559 1 220100490 220100649 160 + 1.674 1.538 -0.463
ENSG00000067704 E004 52.7900753 0.0004372244 4.436369e-04 0.0079518486 1 220102129 220102277 149 + 1.782 1.627 -0.523
ENSG00000067704 E005 29.9654358 0.0005150759 1.882029e-02 0.1219723117 1 220102363 220102412 50 + 1.535 1.401 -0.463
ENSG00000067704 E006 44.4219231 0.0003617118 4.156978e-02 0.1981929276 1 220102495 220102604 110 + 1.688 1.592 -0.328
ENSG00000067704 E007 41.4754778 0.0004551827 6.439002e-03 0.0593880108 1 220102687 220102777 91 + 1.672 1.538 -0.456
ENSG00000067704 E008 57.1361976 0.0002728486 1.177894e-02 0.0895020276 1 220103447 220103562 116 + 1.798 1.693 -0.356
ENSG00000067704 E009 71.1637181 0.0018249530 1.476794e-02 0.1039131254 1 220105891 220106060 170 + 1.891 1.790 -0.337
ENSG00000067704 E010 44.1533933 0.0023886032 4.450390e-02 0.2062267763 1 220107061 220107151 91 + 1.688 1.585 -0.351
ENSG00000067704 E011 73.2524094 0.0005404867 3.639689e-01 0.6526552888 1 220110786 220110937 152 + 1.851 1.882 0.104
ENSG00000067704 E012 86.7441496 0.0001945142 8.713405e-01 0.9557632850 1 220114314 220114450 137 + 1.940 1.932 -0.025
ENSG00000067704 E013 44.3287153 0.0004591221 7.325186e-01 0.8937030866 1 220114451 220114474 24 + 1.657 1.639 -0.060
ENSG00000067704 E014 69.5735533 0.0002405337 5.488955e-01 0.7937296699 1 220125237 220125339 103 + 1.834 1.854 0.067
ENSG00000067704 E015 66.6189770 0.0002612736 7.617291e-01 0.9070787100 1 220126750 220126843 94 + 1.820 1.829 0.031
ENSG00000067704 E016 68.2812950 0.0002813717 9.350376e-01 0.9813208900 1 220134402 220134510 109 + 1.834 1.835 0.003
ENSG00000067704 E017 0.2438580 0.0163312607 7.405703e-01   1 220134615 220134677 63 + 0.079 0.115 0.608
ENSG00000067704 E018 0.1271363 0.0123303722 3.459632e-01   1 220134793 220134846 54 + 0.000 0.115 10.714
ENSG00000067704 E019 64.0536032 0.0005386310 5.231039e-02 0.2272133967 1 220136809 220136911 103 + 1.838 1.760 -0.263
ENSG00000067704 E020 0.3798680 0.0259622726 4.489593e-02   1 220137642 220137917 276 + 0.000 0.280 12.039
ENSG00000067704 E021 96.8086040 0.0001685992 1.788133e-01 0.4538162659 1 220137918 220138043 126 + 2.001 1.958 -0.147
ENSG00000067704 E022 110.2066552 0.0017806795 4.587106e-01 0.7305291436 1 220139008 220139139 132 + 2.051 2.023 -0.092
ENSG00000067704 E023 0.1187032 0.0118364375 8.396063e-01   1 220140181 220140182 2 + 0.079 0.000 -10.865
ENSG00000067704 E024 83.6178744 0.0002643453 2.551239e-01 0.5470398835 1 220140183 220140289 107 + 1.906 1.942 0.120
ENSG00000067704 E025 101.7581135 0.0006612371 3.428859e-05 0.0009682308 1 220141803 220141948 146 + 1.949 2.075 0.424
ENSG00000067704 E026 152.6645804 0.0003020877 2.301614e-05 0.0006946573 1 220142944 220143134 191 + 2.135 2.237 0.342
ENSG00000067704 E027 0.2452102 0.0164144971 7.407972e-01   1 220143135 220143344 210 + 0.079 0.115 0.607
ENSG00000067704 E028 148.0869689 0.0001161893 3.412321e-03 0.0380562723 1 220145509 220145653 145 + 2.137 2.206 0.233
ENSG00000067704 E029 323.9503150 0.0000761419 1.253126e-04 0.0028517334 1 220147493 220148041 549 + 2.480 2.539 0.196

Help

Please Click HERE to learn more details about the results from DEXseq.