ENSG00000068305

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000559036 ENSG00000068305 No_inf pgKDN_inf MEF2A protein_coding retained_intron 94.47981 141.5494 81.24295 3.556945 3.721002 -0.8009154 11.358068 15.894605 10.200617 4.208484 3.4352633 -0.6393744 0.11747500 0.110350 0.121600 0.011250 1.0000000 0.0191013    
ENST00000561125 ENSG00000068305 No_inf pgKDN_inf MEF2A protein_coding retained_intron 94.47981 141.5494 81.24295 3.556945 3.721002 -0.8009154 5.212388 10.459970 2.111387 1.029658 0.7687799 -2.3031774 0.05035833 0.074075 0.027400 -0.046675 0.3659145 0.0191013 TRUE  
MSTRG.10282.1 ENSG00000068305 No_inf pgKDN_inf MEF2A protein_coding   94.47981 141.5494 81.24295 3.556945 3.721002 -0.8009154 5.868573 9.392648 4.426335 1.634375 2.3354435 -1.0836987 0.06169167 0.066000 0.054825 -0.011175 0.8273570 0.0191013 FALSE  
MSTRG.10282.24 ENSG00000068305 No_inf pgKDN_inf MEF2A protein_coding   94.47981 141.5494 81.24295 3.556945 3.721002 -0.8009154 20.684651 29.599923 21.295690 5.396747 4.8997950 -0.4748420 0.21723333 0.209050 0.262500 0.053450 0.8478780 0.0191013 FALSE  
MSTRG.10282.28 ENSG00000068305 No_inf pgKDN_inf MEF2A protein_coding   94.47981 141.5494 81.24295 3.556945 3.721002 -0.8009154 3.155556 9.466668 0.000000 3.218578 0.0000000 -9.8882361 0.02197500 0.065925 0.000000 -0.065925 0.0191013 0.0191013 FALSE  
MSTRG.10282.30 ENSG00000068305 No_inf pgKDN_inf MEF2A protein_coding   94.47981 141.5494 81.24295 3.556945 3.721002 -0.8009154 11.039887 16.331584 7.224056 3.665642 1.6824413 -1.1756711 0.12224167 0.116275 0.091525 -0.024750 0.8509710 0.0191013 FALSE  
MSTRG.10282.31 ENSG00000068305 No_inf pgKDN_inf MEF2A protein_coding   94.47981 141.5494 81.24295 3.556945 3.721002 -0.8009154 8.509507 17.408115 6.320762 2.773201 1.4076940 -1.4601373 0.07686667 0.123475 0.078800 -0.044675 0.6544899 0.0191013 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000068305 E001 1.6219346 0.1747415144 5.294983e-01 0.7808695110 15 99565417 99565494 78 + 0.304 0.443 0.805
ENSG00000068305 E002 2.0024319 0.0325412996 1.950039e-01 0.4751668261 15 99565495 99565509 15 + 0.304 0.519 1.182
ENSG00000068305 E003 4.2093533 0.1149794425 7.236828e-01 0.8890319214 15 99565510 99565562 53 + 0.674 0.705 0.132
ENSG00000068305 E004 6.6822850 0.1603297037 8.059076e-01 0.9281009814 15 99565563 99565669 107 + 0.850 0.868 0.068
ENSG00000068305 E005 0.7521209 0.1563731402 4.110046e-01 0.6927424131 15 99565670 99565699 30 + 0.127 0.275 1.389
ENSG00000068305 E006 0.3811266 0.0320747525 3.089901e-01   15 99565700 99565788 89 + 0.000 0.185 11.561
ENSG00000068305 E007 0.0000000       15 99565789 99565927 139 +      
ENSG00000068305 E008 0.2543986 0.0159916334 5.659390e-01   15 99565928 99565968 41 + 0.000 0.132 11.127
ENSG00000068305 E009 0.5003641 0.0288338538 7.313695e-01 0.8932539387 15 99565969 99565979 11 + 0.127 0.185 0.651
ENSG00000068305 E010 0.8805791 0.0123536968 2.429773e-01 0.5326912760 15 99565980 99565983 4 + 0.127 0.314 1.651
ENSG00000068305 E011 0.8805791 0.0123536968 2.429773e-01 0.5326912760 15 99565984 99565986 3 + 0.127 0.314 1.651
ENSG00000068305 E012 1.1247194 0.0106344508 4.367819e-01 0.7132120041 15 99565987 99565989 3 + 0.224 0.350 0.874
ENSG00000068305 E013 4.7076370 0.0029909903 9.981612e-01 1.0000000000 15 99565990 99566012 23 + 0.732 0.735 0.010
ENSG00000068305 E014 5.4483670 0.0027197061 9.889559e-01 1.0000000000 15 99566013 99566017 5 + 0.784 0.788 0.017
ENSG00000068305 E015 5.8028383 0.0025628226 5.612946e-01 0.8016753526 15 99566018 99566026 9 + 0.851 0.788 -0.246
ENSG00000068305 E016 16.8557621 0.0008113039 2.119812e-02 0.1317013185 15 99566027 99566104 78 + 1.328 1.165 -0.574
ENSG00000068305 E017 4.4736293 0.0031937309 6.460091e-01 0.8502109740 15 99566483 99566599 117 + 0.674 0.735 0.251
ENSG00000068305 E018 0.3617709 0.0167430580 2.580800e-01   15 99566679 99566762 84 + 0.224 0.071 -1.934
ENSG00000068305 E019 32.4181513 0.0010717232 4.926480e-01 0.7547144905 15 99598430 99598511 82 + 1.520 1.485 -0.120
ENSG00000068305 E020 2.0777659 0.0064871556 1.181444e-01 0.3630916749 15 99601941 99602109 169 + 0.607 0.383 -1.104
ENSG00000068305 E021 3.1545329 0.0083597151 2.338462e-03 0.0286837832 15 99620616 99620867 252 + 0.224 0.705 2.590
ENSG00000068305 E022 2.2565806 0.0071629369 1.002950e-01 0.3307840938 15 99620868 99620890 23 + 0.304 0.563 1.388
ENSG00000068305 E023 10.2627184 0.0015584369 8.044494e-03 0.0693753252 15 99620891 99621080 190 + 0.829 1.097 1.001
ENSG00000068305 E024 0.6149137 0.0179967882 7.889491e-01 0.9189724579 15 99626824 99626880 57 + 0.224 0.185 -0.349
ENSG00000068305 E025 0.7512707 0.0133060016 3.511388e-01 0.6414768172 15 99631145 99631187 43 + 0.127 0.275 1.388
ENSG00000068305 E026 112.2475875 0.0004703588 4.267949e-03 0.0444377538 15 99632978 99633173 196 + 2.081 1.998 -0.278
ENSG00000068305 E027 3.8450537 0.0044877067 8.225910e-01 0.9356232070 15 99641267 99641390 124 + 0.642 0.674 0.137
ENSG00000068305 E028 134.2506446 0.0001296920 2.401575e-03 0.0292318940 15 99645561 99645764 204 + 2.155 2.077 -0.261
ENSG00000068305 E029 0.3726934 0.0165986368 1.000000e+00   15 99645765 99645831 67 + 0.127 0.132 0.066
ENSG00000068305 E030 3.1213600 0.0199593483 2.935805e-01 0.5871797764 15 99657413 99657538 126 + 0.481 0.640 0.729
ENSG00000068305 E031 76.4310676 0.0002115288 8.626571e-01 0.9525857000 15 99671323 99671454 132 + 1.864 1.861 -0.010
ENSG00000068305 E032 12.8760863 0.0011120997 4.668875e-03 0.0471556371 15 99671455 99671519 65 + 0.926 1.186 0.947
ENSG00000068305 E033 36.9144001 0.0053502363 9.780052e-01 0.9968544101 15 99671520 99671657 138 + 1.550 1.553 0.008
ENSG00000068305 E034 0.7610560 0.0212777639 6.284671e-02 0.2520504693 15 99671658 99671669 12 + 0.000 0.314 12.620
ENSG00000068305 E035 125.6137676 0.0034620291 5.719456e-01 0.8080712758 15 99674393 99674612 220 + 2.087 2.069 -0.058
ENSG00000068305 E036 52.0635134 0.0004808724 3.096893e-01 0.6030103588 15 99675399 99675458 60 + 1.725 1.684 -0.140
ENSG00000068305 E037 94.7886998 0.0001702247 3.180079e-01 0.6107409734 15 99690241 99690428 188 + 1.973 1.944 -0.097
ENSG00000068305 E038 3.9927769 0.0251337156 3.022409e-01 0.5953855987 15 99694076 99694199 124 + 0.569 0.720 0.651
ENSG00000068305 E039 3.4719826 0.0416469569 8.327187e-01 0.9396922034 15 99695071 99695159 89 + 0.607 0.640 0.144
ENSG00000068305 E040 3.1297268 0.0045279398 1.217408e-01 0.3692896968 15 99703362 99703385 24 + 0.430 0.657 1.066
ENSG00000068305 E041 13.1936182 0.0012414878 4.722976e-06 0.0001793866 15 99703386 99703953 568 + 0.784 1.229 1.651
ENSG00000068305 E042 4.9968052 0.0027627727 1.102890e-01 0.3484463084 15 99706595 99706728 134 + 0.607 0.812 0.850
ENSG00000068305 E043 71.1699786 0.0002269346 5.475994e-02 0.2330668118 15 99706729 99706855 127 + 1.876 1.808 -0.229
ENSG00000068305 E044 68.4513122 0.0002679028 5.450705e-01 0.7911363339 15 99710634 99710760 127 + 1.796 1.823 0.090
ENSG00000068305 E045 206.2229728 0.0008660184 7.791891e-01 0.9149983786 15 99712390 99712835 446 + 2.282 2.292 0.034
ENSG00000068305 E046 1302.6602599 0.0005554784 6.181938e-01 0.8348146965 15 99712836 99715467 2632 + 3.083 3.090 0.025
ENSG00000068305 E047 159.2648111 0.0030608695 2.068041e-02 0.1295594207 15 99715468 99716488 1021 + 2.120 2.203 0.275

Help

Please Click HERE to learn more details about the results from DEXseq.