ENSG00000068903

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000249396 ENSG00000068903 No_inf pgKDN_inf SIRT2 protein_coding protein_coding 30.23268 27.49046 28.76913 0.3260024 1.333147 0.06556722 3.729412 2.442585 3.8295306 1.1541534 1.8461158 0.6466267 0.11998333 0.088775 0.128400 0.039625 0.8483137511 0.0001707838 FALSE TRUE
ENST00000392081 ENSG00000068903 No_inf pgKDN_inf SIRT2 protein_coding protein_coding 30.23268 27.49046 28.76913 0.3260024 1.333147 0.06556722 20.350861 16.020217 21.7214897 1.1562615 1.6239227 0.4389931 0.67419167 0.583025 0.763700 0.180675 0.3118642653 0.0001707838 FALSE TRUE
ENST00000462654 ENSG00000068903 No_inf pgKDN_inf SIRT2 protein_coding retained_intron 30.23268 27.49046 28.76913 0.3260024 1.333147 0.06556722 1.297574 2.865096 0.0505729 0.5995387 0.0505729 -5.5687938 0.04560833 0.104750 0.002000 -0.102750 0.0001707838 0.0001707838 FALSE TRUE
ENST00000496069 ENSG00000068903 No_inf pgKDN_inf SIRT2 protein_coding retained_intron 30.23268 27.49046 28.76913 0.3260024 1.333147 0.06556722 1.740985 3.053582 0.6135567 0.5497455 0.3190970 -2.2966270 0.05919167 0.110975 0.020875 -0.090100 0.1122209658 0.0001707838   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000068903 E001 0.0000000       19 38878555 38878556 2 -      
ENSG00000068903 E002 0.0000000       19 38878557 38878559 3 -      
ENSG00000068903 E003 0.4715300 0.1844843604 6.952273e-02   19 38878560 38878568 9 - 0.297 0.000 -11.645
ENSG00000068903 E004 98.2945338 0.0023196162 8.251819e-01 9.366773e-01 19 38878569 38879293 725 - 1.991 2.002 0.037
ENSG00000068903 E005 11.6188496 0.0013029644 6.945060e-01 8.752285e-01 19 38879294 38879310 17 - 1.116 1.087 -0.105
ENSG00000068903 E006 0.2533610 0.0160229445 2.487477e-01   19 38879311 38879433 123 - 0.000 0.172 12.792
ENSG00000068903 E007 20.4209623 0.0045093417 6.398794e-01 8.469228e-01 19 38879434 38879500 67 - 1.345 1.317 -0.100
ENSG00000068903 E008 0.6265540 0.1868416826 2.405276e-01 5.297540e-01 19 38879501 38879631 131 - 0.095 0.296 1.987
ENSG00000068903 E009 17.1858363 0.0008321526 4.567519e-01 7.289927e-01 19 38879632 38879702 71 - 1.230 1.285 0.193
ENSG00000068903 E010 7.0117734 0.0152604883 1.838590e-05 5.740959e-04 19 38879703 38880684 982 - 0.569 1.078 2.019
ENSG00000068903 E011 14.2453138 0.0069186760 5.484639e-01 7.934693e-01 19 38880685 38880736 52 - 1.155 1.207 0.185
ENSG00000068903 E012 14.8118620 0.0043072063 8.585275e-01 9.506605e-01 19 38880821 38880849 29 - 1.204 1.194 -0.038
ENSG00000068903 E013 17.2310026 0.0008912144 4.860363e-01 7.498679e-01 19 38880850 38880897 48 - 1.283 1.239 -0.157
ENSG00000068903 E014 0.8506782 0.4275234512 6.767828e-01 8.659958e-01 19 38880898 38881099 202 - 0.297 0.238 -0.426
ENSG00000068903 E015 19.2377966 0.0007416942 7.709780e-01 9.116845e-01 19 38881100 38881155 56 - 1.294 1.317 0.078
ENSG00000068903 E016 1.6214952 0.0099071976 5.256127e-02 2.278810e-01 19 38881156 38881431 276 - 0.240 0.536 1.723
ENSG00000068903 E017 17.4806943 0.0036843135 9.375069e-02 3.184100e-01 19 38881432 38881491 60 - 1.197 1.322 0.437
ENSG00000068903 E018 9.2753497 0.0253251765 4.873700e-02 2.175257e-01 19 38883627 38883638 12 - 0.883 1.104 0.816
ENSG00000068903 E019 26.3790819 0.0117506283 5.763562e-01 8.104891e-01 19 38883639 38883756 118 - 1.416 1.455 0.134
ENSG00000068903 E020 22.5934470 0.0006595216 1.167970e-03 1.685665e-02 19 38889087 38889155 69 - 1.463 1.268 -0.677
ENSG00000068903 E021 0.0000000       19 38889156 38889168 13 -      
ENSG00000068903 E022 0.0000000       19 38889169 38889230 62 -      
ENSG00000068903 E023 0.0000000       19 38889231 38889253 23 -      
ENSG00000068903 E024 0.5080420 0.0159484196 4.702702e-02 2.129959e-01 19 38889254 38889323 70 - 0.000 0.295 13.722
ENSG00000068903 E025 0.1176306 0.0117215613 5.283585e-01   19 38889324 38889688 365 - 0.095 0.000 -12.675
ENSG00000068903 E026 13.7449642 0.0010232796 3.767006e-02 1.872187e-01 19 38889689 38889696 8 - 1.242 1.087 -0.556
ENSG00000068903 E027 19.2977721 0.0007931389 2.826173e-01 5.762421e-01 19 38889697 38889745 49 - 1.341 1.274 -0.233
ENSG00000068903 E028 0.0000000       19 38889746 38889854 109 -      
ENSG00000068903 E029 11.9009414 0.0016709400 6.770459e-01 8.661023e-01 19 38889855 38889859 5 - 1.090 1.128 0.135
ENSG00000068903 E030 14.2131534 0.0010638902 9.283178e-01 9.787530e-01 19 38889860 38889882 23 - 1.177 1.187 0.036
ENSG00000068903 E031 12.1554195 0.0011426003 5.390856e-01 7.876180e-01 19 38889883 38889898 16 - 1.090 1.143 0.191
ENSG00000068903 E032 18.1463654 0.0007795900 6.980493e-01 8.768128e-01 19 38889899 38889961 63 - 1.266 1.296 0.103
ENSG00000068903 E033 0.1272623 0.0123556474 5.482152e-01   19 38889962 38890102 141 - 0.000 0.095 11.852
ENSG00000068903 E034 12.6935266 0.0012034433 2.844681e-01 5.782052e-01 19 38890103 38890144 42 - 1.177 1.095 -0.292
ENSG00000068903 E035 0.0000000       19 38890565 38890662 98 -      
ENSG00000068903 E036 0.0000000       19 38891794 38891966 173 -      
ENSG00000068903 E037 20.7483665 0.0133078507 7.472850e-03 6.601813e-02 19 38893414 38893527 114 - 1.432 1.226 -0.719
ENSG00000068903 E038 1.8842029 0.0203045344 4.009319e-03 4.247468e-02 19 38893528 38893818 291 - 0.174 0.620 2.687
ENSG00000068903 E039 15.1716388 0.0010685592 6.823268e-03 6.202699e-02 19 38893819 38893867 49 - 1.300 1.104 -0.696
ENSG00000068903 E040 2.7184872 0.0054837427 2.174494e-01 5.038847e-01 19 38893868 38893971 104 - 0.472 0.644 0.794
ENSG00000068903 E041 1.0040024 0.0739216438 3.877621e-02 1.904759e-01 19 38893972 38893998 27 - 0.095 0.432 2.793
ENSG00000068903 E042 5.5286144 0.0027059909 5.776379e-07 2.834788e-05 19 38893999 38894410 412 - 0.394 1.011 2.649
ENSG00000068903 E043 0.9593074 0.0138482665 1.464339e-01 4.074584e-01 19 38898379 38898379 1 - 0.394 0.172 -1.599
ENSG00000068903 E044 3.1620682 0.0195798589 4.372827e-01 7.135710e-01 19 38898380 38898425 46 - 0.671 0.566 -0.461
ENSG00000068903 E045 2.5923833 0.0055031777 2.962969e-01 5.893376e-01 19 38898426 38898793 368 - 0.472 0.620 0.687
ENSG00000068903 E046 1.1224497 0.2016755122 1.906510e-01 4.698887e-01 19 38898794 38898914 121 - 0.174 0.432 1.794
ENSG00000068903 E047 0.6259247 0.1768554614 2.375785e-01 5.265592e-01 19 38898915 38898918 4 - 0.095 0.295 1.987
ENSG00000068903 E048 0.2537079 0.2827756337 3.130923e-01   19 38899489 38899505 17 - 0.000 0.172 12.162
ENSG00000068903 E049 12.8053449 0.0011536040 1.737217e-01 4.471665e-01 19 38899506 38899862 357 - 1.191 1.087 -0.373

Help

Please Click HERE to learn more details about the results from DEXseq.