ENSG00000069329

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000562420 ENSG00000069329 No_inf pgKDN_inf VPS35 protein_coding retained_intron 52.41342 23.70843 67.05209 1.546666 7.290721 1.499489 5.922973 2.497377 7.40966 1.6118169 3.0147590 1.5651743 0.1073167 0.096225 0.107325 0.01110 0.8502271 0.0437503 FALSE FALSE
ENST00000568642 ENSG00000069329 No_inf pgKDN_inf VPS35 protein_coding protein_coding_CDS_not_defined 52.41342 23.70843 67.05209 1.546666 7.290721 1.499489 14.016050 1.107642 18.05110 1.1076419 6.2029577 4.0143556 0.2131000 0.045875 0.251525 0.20565 0.0437503 0.0437503 FALSE TRUE
ENST00000568784 ENSG00000069329 No_inf pgKDN_inf VPS35 protein_coding nonsense_mediated_decay 52.41342 23.70843 67.05209 1.546666 7.290721 1.499489 21.918123 11.813304 29.04235 0.8875565 0.5670005 1.2970214 0.4423333 0.503050 0.446350 -0.05670 0.8353706 0.0437503 FALSE TRUE
ENST00000647959 ENSG00000069329 No_inf pgKDN_inf VPS35 protein_coding nonsense_mediated_decay 52.41342 23.70843 67.05209 1.546666 7.290721 1.499489 8.720581 7.127026 10.63160 0.3395071 0.5134488 0.5763196 0.1989167 0.306550 0.164500 -0.14205 0.2122096 0.0437503 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000069329 E001 5.7926630 0.1718053570 1.684106e-01 0.4396446679 16 46656132 46658076 1945 - 0.663 0.999 1.317
ENSG00000069329 E002 46.0631229 0.0003390926 2.674506e-06 0.0001091224 16 46658077 46659676 1600 - 1.571 1.775 0.692
ENSG00000069329 E003 212.7319189 0.0002428524 6.456815e-05 0.0016426503 16 46659677 46660651 975 - 2.285 2.361 0.253
ENSG00000069329 E004 55.9418940 0.0002592048 3.035279e-01 0.5968743913 16 46661718 46661826 109 - 1.725 1.765 0.135
ENSG00000069329 E005 34.4953540 0.0004064178 1.554749e-01 0.4213549869 16 46661827 46661861 35 - 1.507 1.579 0.244
ENSG00000069329 E006 73.0939947 0.0002163981 5.053094e-01 0.7641302629 16 46662243 46662482 240 - 1.846 1.868 0.074
ENSG00000069329 E007 53.9855448 0.0003276712 5.890270e-01 0.8177607717 16 46662983 46663162 180 - 1.734 1.709 -0.082
ENSG00000069329 E008 31.8228083 0.0004516341 2.374438e-01 0.5264656732 16 46668930 46669052 123 - 1.477 1.539 0.211
ENSG00000069329 E009 0.0000000       16 46669053 46669214 162 -      
ENSG00000069329 E010 23.2133141 0.0006411440 2.273290e-01 0.5157213817 16 46671705 46671860 156 - 1.340 1.414 0.255
ENSG00000069329 E011 27.3934997 0.0030836602 2.030518e-01 0.4856516541 16 46672265 46672417 153 - 1.467 1.385 -0.281
ENSG00000069329 E012 23.8095573 0.0006661188 4.988033e-03 0.0495258819 16 46672418 46672472 55 - 1.439 1.254 -0.643
ENSG00000069329 E013 49.1492982 0.0003142715 1.297851e-03 0.0183097786 16 46674314 46674462 149 - 1.734 1.586 -0.500
ENSG00000069329 E014 44.7862856 0.0154919327 1.190217e-02 0.0900956456 16 46674564 46674660 97 - 1.702 1.526 -0.600
ENSG00000069329 E015 0.0000000       16 46676505 46676577 73 -      
ENSG00000069329 E016 0.0000000       16 46676578 46676582 5 -      
ENSG00000069329 E017 41.7753482 0.0015336991 9.206826e-02 0.3151220101 16 46676583 46676692 110 - 1.646 1.559 -0.295
ENSG00000069329 E018 36.1446795 0.0004799853 3.382399e-01 0.6300409176 16 46677315 46677398 84 - 1.573 1.522 -0.174
ENSG00000069329 E019 0.1170040 0.0117256617 1.000000e+00   16 46677399 46677686 288 - 0.072 0.000 -11.449
ENSG00000069329 E020 55.0373296 0.0002733494 3.394233e-01 0.6311265363 16 46678943 46679156 214 - 1.748 1.707 -0.140
ENSG00000069329 E021 10.1795077 0.0017081004 9.186949e-01 0.9743996150 16 46680671 46680674 4 - 1.038 1.027 -0.039
ENSG00000069329 E022 11.9516321 0.0029105672 2.339840e-01 0.5230311487 16 46680675 46680686 12 - 1.134 1.027 -0.387
ENSG00000069329 E023 36.9714153 0.0004655620 1.357304e-01 0.3915952150 16 46680687 46680853 167 - 1.591 1.513 -0.267
ENSG00000069329 E024 25.3423277 0.0041064439 1.934057e-01 0.4731549860 16 46681377 46681500 124 - 1.436 1.348 -0.306
ENSG00000069329 E025 0.5974130 0.0150091332 4.808217e-01 0.7460464168 16 46681501 46681520 20 - 0.236 0.125 -1.116
ENSG00000069329 E026 0.2357071 0.0156589720 5.402542e-01   16 46681521 46681755 235 - 0.134 0.000 -12.380
ENSG00000069329 E027 0.1170040 0.0117256617 1.000000e+00   16 46681756 46682078 323 - 0.072 0.000 -11.449
ENSG00000069329 E028 14.6567554 0.0036532128 1.643086e-02 0.1114834742 16 46682079 46682175 97 - 1.245 1.040 -0.733
ENSG00000069329 E029 0.0000000       16 46682478 46682642 165 -      
ENSG00000069329 E030 0.1272623 0.0123508407 2.788709e-01   16 46682643 46682666 24 - 0.000 0.125 11.754
ENSG00000069329 E031 0.1272623 0.0123508407 2.788709e-01   16 46682667 46682684 18 - 0.000 0.125 11.754
ENSG00000069329 E032 0.2455571 0.0164402965 6.309748e-01   16 46682882 46683507 626 - 0.072 0.125 0.884
ENSG00000069329 E033 12.4552445 0.0026828572 5.265216e-01 0.7788429899 16 46683508 46683606 99 - 1.134 1.078 -0.201
ENSG00000069329 E034 0.1272623 0.0123508407 2.788709e-01   16 46683607 46683607 1 - 0.000 0.125 11.754
ENSG00000069329 E035 0.0000000       16 46688314 46689130 817 -      
ENSG00000069329 E036 6.5278678 0.0021598053 5.820963e-01 0.8138722833 16 46689131 46689194 64 - 0.885 0.823 -0.238
ENSG00000069329 E037 0.0000000       16 46689335 46689518 184 -      

Help

Please Click HERE to learn more details about the results from DEXseq.