ENSG00000069399

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000164227 ENSG00000069399 No_inf pgKDN_inf BCL3 protein_coding protein_coding 39.57169 29.43091 38.65325 0.8398743 1.929697 0.3931407 22.643253 11.709026 27.665300 1.140473 1.471678 1.2397463 0.56150833 0.400850 0.715625 0.314775 0.0004928022 0.0004928022 FALSE TRUE
ENST00000473473 ENSG00000069399 No_inf pgKDN_inf BCL3 protein_coding retained_intron 39.57169 29.43091 38.65325 0.8398743 1.929697 0.3931407 2.505644 4.090248 2.241452 1.943769 1.763884 -0.8648555 0.07318333 0.142075 0.057575 -0.084500 0.7034827403 0.0004928022 FALSE FALSE
ENST00000474300 ENSG00000069399 No_inf pgKDN_inf BCL3 protein_coding retained_intron 39.57169 29.43091 38.65325 0.8398743 1.929697 0.3931407 8.588918 7.962129 5.561089 2.753819 2.024085 -0.5170057 0.21528333 0.265675 0.143350 -0.122325 0.8503023177 0.0004928022 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000069399 E001 0.2448930 0.0161095636 0.7976268086   19 44747705 44747792 88 + 0.082 0.110 0.472
ENSG00000069399 E002 0.1176306 0.0116837248 0.7492217668   19 44747793 44747835 43 + 0.082 0.000 -8.320
ENSG00000069399 E003 1.4702471 0.0093335852 0.5739032847 0.809035776 19 44747836 44748128 293 + 0.352 0.436 0.472
ENSG00000069399 E004 2.8393509 0.0067916494 0.0703104419 0.268278979 19 44748227 44748694 468 + 0.458 0.702 1.109
ENSG00000069399 E005 0.4993265 0.0156615038 0.1861897119   19 44748695 44748707 13 + 0.082 0.271 2.057
ENSG00000069399 E006 24.6975411 0.0006349690 0.0507621464 0.222857599 19 44748708 44749046 339 + 1.454 1.338 -0.403
ENSG00000069399 E007 14.6590846 0.0011494331 0.2810931646 0.574347581 19 44751227 44751320 94 + 1.155 1.234 0.279
ENSG00000069399 E008 13.3902394 0.0011801632 0.9994432339 1.000000000 19 44751321 44751380 60 + 1.155 1.154 -0.005
ENSG00000069399 E009 2.7226982 0.0373487226 0.0659458921 0.258614538 19 44755149 44755474 326 + 0.425 0.702 1.279
ENSG00000069399 E010 0.7420473 0.0141190770 0.2243413505 0.511859506 19 44756145 44756231 87 + 0.151 0.333 1.472
ENSG00000069399 E011 23.8405605 0.0005615165 0.0211368419 0.131481706 19 44756232 44756340 109 + 1.447 1.308 -0.484
ENSG00000069399 E012 30.2508675 0.0042929055 0.0000467089 0.001261491 19 44757017 44757221 205 + 1.582 1.338 -0.842
ENSG00000069399 E013 21.0420310 0.0007082311 0.8300036993 0.938360364 19 44757327 44757415 89 + 1.346 1.332 -0.051
ENSG00000069399 E014 0.7245467 0.0140948173 0.6734448524 0.864799397 19 44757589 44757645 57 + 0.263 0.198 -0.528
ENSG00000069399 E015 13.1629045 0.0012225610 0.7228596782 0.888603311 19 44757646 44757656 11 + 1.136 1.163 0.096
ENSG00000069399 E016 21.4295218 0.0022345184 0.9195456570 0.974921015 19 44757657 44757723 67 + 1.350 1.343 -0.025
ENSG00000069399 E017 31.0854194 0.0049745561 0.6940671901 0.874922217 19 44758246 44758413 168 + 1.493 1.515 0.073
ENSG00000069399 E018 0.7348421 0.4158771216 0.8908743613 0.963657304 19 44758414 44758473 60 + 0.210 0.271 0.471
ENSG00000069399 E019 0.8643033 0.2803738127 0.4428092484 0.718037363 19 44758474 44758527 54 + 0.211 0.333 0.886
ENSG00000069399 E020 1.7266905 0.1046060235 0.3185682346 0.611261732 19 44758528 44758656 129 + 0.352 0.519 0.886
ENSG00000069399 E021 0.9975795 0.0127640881 0.0598054169 0.245288620 19 44758657 44758723 67 + 0.151 0.436 2.057
ENSG00000069399 E022 32.1143095 0.0004625873 0.1971782469 0.478410475 19 44758724 44758841 118 + 1.487 1.551 0.219
ENSG00000069399 E023 95.8739830 0.0001822721 0.0410486506 0.196636981 19 44759428 44760044 617 + 1.959 2.012 0.177

Help

Please Click HERE to learn more details about the results from DEXseq.