ENSG00000070010

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000399523 ENSG00000070010 No_inf pgKDN_inf UFD1 protein_coding protein_coding 58.13194 57.9134 59.39949 4.434436 2.72076 0.03654715 27.249866 20.258830 31.883060 1.21047459 1.2270006 0.6539797 0.47238333 0.354975 0.537675 0.182700 0.04030164 0.04030164 FALSE TRUE
ENST00000459854 ENSG00000070010 No_inf pgKDN_inf UFD1 protein_coding retained_intron 58.13194 57.9134 59.39949 4.434436 2.72076 0.03654715 3.124197 4.267304 2.096185 0.08717332 0.1121567 -1.0220692 0.05483333 0.074850 0.035300 -0.039550 0.39289462 0.04030164 FALSE TRUE
ENST00000474226 ENSG00000070010 No_inf pgKDN_inf UFD1 protein_coding protein_coding 58.13194 57.9134 59.39949 4.434436 2.72076 0.03654715 9.165755 12.997232 6.641468 6.37508313 1.8371977 -0.9675694 0.14462500 0.206925 0.109100 -0.097825 0.90305456 0.04030164   FALSE
MSTRG.19032.3 ENSG00000070010 No_inf pgKDN_inf UFD1 protein_coding   58.13194 57.9134 59.39949 4.434436 2.72076 0.03654715 14.312684 15.615970 13.993965 2.24253567 1.9922142 -0.1581104 0.25291667 0.278075 0.237275 -0.040800 0.86981380 0.04030164 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000070010 E001 0.000000       22 19449911 19450098 188 -      
ENSG00000070010 E002 6.433810 0.0194797446 1.865159e-01 4.644941e-01 22 19450099 19450620 522 - 0.776 0.932 0.605
ENSG00000070010 E003 1.507324 0.0087467535 2.988085e-02 1.626070e-01 22 19450621 19450624 4 - 0.183 0.517 2.130
ENSG00000070010 E004 16.748488 0.0093040768 4.020045e-01 6.851343e-01 22 19450625 19450744 120 - 1.209 1.276 0.235
ENSG00000070010 E005 24.477967 0.0060402569 6.380878e-06 2.315924e-04 22 19450745 19451877 1133 - 1.209 1.516 1.069
ENSG00000070010 E006 3.958280 0.0036103765 2.991461e-01 5.920135e-01 22 19451878 19452000 123 - 0.617 0.747 0.545
ENSG00000070010 E007 35.785978 0.0004436074 4.600715e-09 3.455918e-07 22 19452001 19454748 2748 - 1.376 1.672 1.016
ENSG00000070010 E008 19.761697 0.0090658626 8.884031e-01 9.627268e-01 22 19454749 19454801 53 - 1.320 1.311 -0.031
ENSG00000070010 E009 18.099320 0.0010638531 1.403989e-01 3.987430e-01 22 19454802 19454830 29 - 1.331 1.231 -0.348
ENSG00000070010 E010 16.917082 0.0009173097 5.383523e-01 7.871254e-01 22 19455680 19455768 89 - 1.274 1.231 -0.150
ENSG00000070010 E011 0.000000       22 19456587 19456634 48 -      
ENSG00000070010 E012 0.000000       22 19456853 19456879 27 -      
ENSG00000070010 E013 0.000000       22 19456880 19456918 39 -      
ENSG00000070010 E014 15.625706 0.0062761836 4.847435e-01 7.487943e-01 22 19458071 19458139 69 - 1.187 1.243 0.197
ENSG00000070010 E015 34.018543 0.0006600475 8.774847e-01 9.584351e-01 22 19465202 19465274 73 - 1.538 1.546 0.027
ENSG00000070010 E016 6.262218 0.0025327285 8.240808e-01 9.361749e-01 22 19465275 19467402 2128 - 0.846 0.870 0.092
ENSG00000070010 E017 1.449133 0.0179055419 1.721552e-01 4.448340e-01 22 19467403 19467872 470 - 0.490 0.282 -1.192
ENSG00000070010 E018 25.209161 0.0012188040 2.150212e-01 5.006799e-01 22 19467873 19467894 22 - 1.454 1.383 -0.248
ENSG00000070010 E019 43.434633 0.0003446775 6.735727e-01 8.648401e-01 22 19467895 19468003 109 - 1.655 1.637 -0.061
ENSG00000070010 E020 47.495547 0.0056175687 1.155463e-01 3.583390e-01 22 19471687 19471808 122 - 1.725 1.646 -0.267
ENSG00000070010 E021 28.862747 0.0048854433 7.950692e-02 2.892106e-01 22 19475068 19475100 33 - 1.528 1.422 -0.364
ENSG00000070010 E022 19.966057 0.0007800545 1.229912e-03 1.755579e-02 22 19475470 19475495 26 - 1.421 1.213 -0.726
ENSG00000070010 E023 30.402215 0.0011225785 1.623896e-02 1.107247e-01 22 19475496 19475602 107 - 1.560 1.433 -0.436
ENSG00000070010 E024 0.000000       22 19478763 19478824 62 -      
ENSG00000070010 E025 0.126854 0.0123521102 6.140469e-01   22 19478825 19479082 258 - 0.000 0.090 9.268
ENSG00000070010 E026 25.478874 0.0069467756 5.383924e-01 7.871254e-01 22 19479083 19479202 120 - 1.442 1.403 -0.136

Help

Please Click HERE to learn more details about the results from DEXseq.