ENSG00000070214

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374720 ENSG00000070214 No_inf pgKDN_inf SLC44A1 protein_coding protein_coding 32.22425 23.28072 38.88845 0.2800721 0.8294853 0.7399576 9.122645 11.0643888 8.872503 0.2577199 0.3542507 -0.3181888 0.30666667 0.475850 0.228500 -0.247350 0.004206605 0.004206605 FALSE TRUE
ENST00000374724 ENSG00000070214 No_inf pgKDN_inf SLC44A1 protein_coding protein_coding 32.22425 23.28072 38.88845 0.2800721 0.8294853 0.7399576 19.773575 11.4252203 25.118324 0.2250578 0.8602172 1.1358303 0.59871667 0.490625 0.645475 0.154850 0.111795952 0.004206605 FALSE TRUE
ENST00000699289 ENSG00000070214 No_inf pgKDN_inf SLC44A1 protein_coding protein_coding 32.22425 23.28072 38.88845 0.2800721 0.8294853 0.7399576 3.134454 0.7911075 4.716682 0.3241192 0.1641672 2.5607601 0.08930833 0.033525 0.121650 0.088125 0.202338940 0.004206605 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000070214 E001 1.5994295 0.0104868260 5.257233e-01 7.783245e-01 9 105244622 105244650 29 + 0.367 0.462 0.517
ENSG00000070214 E002 9.2724092 0.0334819337 8.346248e-01 9.403914e-01 9 105244651 105244803 153 + 1.022 0.998 -0.088
ENSG00000070214 E003 7.5790199 0.0019070981 5.879039e-01 8.171602e-01 9 105244804 105244904 101 + 0.907 0.961 0.201
ENSG00000070214 E004 0.0000000       9 105294666 105294798 133 +      
ENSG00000070214 E005 9.1135250 0.0134357952 4.415020e-01 7.169688e-01 9 105299220 105299309 90 + 1.039 0.961 -0.290
ENSG00000070214 E006 0.0000000       9 105299743 105299937 195 +      
ENSG00000070214 E007 22.1849031 0.0010095650 1.641431e-02 1.114009e-01 9 105309724 105309866 143 + 1.429 1.276 -0.531
ENSG00000070214 E008 32.8715929 0.0004326938 7.448625e-03 6.590127e-02 9 105335563 105335699 137 + 1.589 1.449 -0.480
ENSG00000070214 E009 35.0406320 0.0004107932 2.035233e-03 2.587044e-02 9 105348358 105348451 94 + 1.622 1.465 -0.536
ENSG00000070214 E010 0.1186381 0.0117784802 6.581942e-01   9 105355917 105356211 295 + 0.087 0.000 -10.913
ENSG00000070214 E011 50.0680825 0.0004848372 1.669782e-02 1.126852e-01 9 105356212 105356381 170 + 1.752 1.650 -0.346
ENSG00000070214 E012 0.1176306 0.0117193907 6.581146e-01   9 105357151 105357243 93 + 0.087 0.000 -10.914
ENSG00000070214 E013 27.7952252 0.0005024677 4.600547e-05 1.245612e-03 9 105358344 105358433 90 + 1.553 1.318 -0.810
ENSG00000070214 E014 45.0115550 0.0003430143 3.266900e-09 2.549884e-07 9 105361191 105361330 140 + 1.769 1.496 -0.926
ENSG00000070214 E015 52.2572246 0.0002849478 1.266420e-06 5.720525e-05 9 105362821 105363007 187 + 1.809 1.605 -0.691
ENSG00000070214 E016 52.0005129 0.0002686936 1.941334e-04 4.083616e-03 9 105364555 105364720 166 + 1.789 1.634 -0.527
ENSG00000070214 E017 45.7823313 0.0004157206 4.849599e-05 1.297412e-03 9 105365483 105365639 157 + 1.745 1.562 -0.621
ENSG00000070214 E018 29.1721935 0.0005010789 9.343816e-01 9.810672e-01 9 105366346 105366429 84 + 1.476 1.481 0.016
ENSG00000070214 E019 52.2877432 0.0002956542 5.105658e-01 7.680560e-01 9 105374598 105374735 138 + 1.738 1.711 -0.091
ENSG00000070214 E020 82.3149576 0.0002120210 5.154066e-01 7.714885e-01 9 105383123 105383359 237 + 1.910 1.931 0.071
ENSG00000070214 E021 47.9172305 0.0033484673 6.928407e-01 8.744165e-01 9 105385422 105385502 81 + 1.698 1.678 -0.067
ENSG00000070214 E022 0.8621962 0.1510432719 5.841557e-01 8.151158e-01 9 105385503 105385703 201 + 0.221 0.319 0.709
ENSG00000070214 E023 0.1272623 0.0123488747 4.380873e-01   9 105386688 105386741 54 + 0.000 0.104 10.373
ENSG00000070214 E024 19.9861222 0.0010376173 6.794250e-01 8.675527e-01 9 105389033 105389108 76 + 1.334 1.306 -0.095
ENSG00000070214 E025 18.1403007 0.0007667622 1.628533e-01 4.313800e-01 9 105389109 105389186 78 + 1.234 1.329 0.333
ENSG00000070214 E026 103.9674546 0.0001823551 3.266213e-02 1.712951e-01 9 105389187 105389882 696 + 1.990 2.052 0.206
ENSG00000070214 E027 14.2349433 0.0009466194 1.005583e-01 3.311057e-01 9 105389883 105389903 21 + 1.119 1.244 0.444
ENSG00000070214 E028 307.0337651 0.0000891011 4.516236e-11 4.738885e-09 9 105389904 105395496 5593 + 2.438 2.538 0.334
ENSG00000070214 E029 78.3461807 0.0002289796 8.791366e-20 2.335732e-17 9 105395497 105397346 1850 + 1.727 2.036 1.039
ENSG00000070214 E030 35.5190291 0.0004753324 8.810121e-01 9.600356e-01 9 105438281 105439171 891 + 1.558 1.566 0.026

Help

Please Click HERE to learn more details about the results from DEXseq.