ENSG00000070961

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000428670 ENSG00000070961 No_inf pgKDN_inf ATP2B1 protein_coding protein_coding 236.493 30.08247 315.2546 2.620609 7.317302 3.389089 58.786681 5.787942 76.479073 2.7745662 4.6290375 3.721641 0.23339167 0.199900 0.242025 0.042125 7.505487e-01 2.337112e-07 FALSE  
ENST00000550716 ENSG00000070961 No_inf pgKDN_inf ATP2B1 protein_coding protein_coding 236.493 30.08247 315.2546 2.620609 7.317302 3.389089 68.235355 5.932205 94.211428 3.9474547 7.5382466 3.986985 0.25414167 0.176725 0.298025 0.121300 6.635338e-01 2.337112e-07 FALSE  
ENST00000552275 ENSG00000070961 No_inf pgKDN_inf ATP2B1 protein_coding retained_intron 236.493 30.08247 315.2546 2.620609 7.317302 3.389089 4.467075 2.016359 4.577103 0.5018377 0.7370442 1.178694 0.03318333 0.066400 0.014500 -0.051900 2.652080e-02 2.337112e-07    
ENST00000635033 ENSG00000070961 No_inf pgKDN_inf ATP2B1 protein_coding protein_coding 236.493 30.08247 315.2546 2.620609 7.317302 3.389089 37.427268 4.814443 51.170523 1.9709654 3.0915299 3.407160 0.16128333 0.167475 0.162450 -0.005025 9.148631e-01 2.337112e-07 FALSE  
ENST00000705822 ENSG00000070961 No_inf pgKDN_inf ATP2B1 protein_coding protein_coding 236.493 30.08247 315.2546 2.620609 7.317302 3.389089 18.732188 0.000000 22.155091 0.0000000 3.6028499 11.114074 0.05470000 0.000000 0.070450 0.070450 2.337112e-07 2.337112e-07 FALSE  
MSTRG.6942.1 ENSG00000070961 No_inf pgKDN_inf ATP2B1 protein_coding   236.493 30.08247 315.2546 2.620609 7.317302 3.389089 32.640669 6.087385 51.002711 3.5280195 7.2118490 3.064594 0.16216667 0.210725 0.163450 -0.047275 8.435127e-01 2.337112e-07 FALSE  
MSTRG.6942.3 ENSG00000070961 No_inf pgKDN_inf ATP2B1 protein_coding   236.493 30.08247 315.2546 2.620609 7.317302 3.389089 5.682405 2.354481 6.354000 2.3544807 2.6873755 1.428410 0.03890000 0.073975 0.019800 -0.054175 7.903973e-01 2.337112e-07 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000070961 E001 0.0000000       12 89588045 89588048 4 -      
ENSG00000070961 E002 710.2379421 1.158209e-04 1.058050e-07 6.142102e-06 12 89588049 89590439 2391 - 2.635 2.723 0.295
ENSG00000070961 E003 127.7483908 8.095136e-04 8.415969e-01 9.431635e-01 12 89590440 89590527 88 - 1.903 1.914 0.036
ENSG00000070961 E004 465.0564095 5.185910e-05 7.302255e-01 8.926559e-01 12 89590528 89591102 575 - 2.461 2.470 0.031
ENSG00000070961 E005 219.1415715 8.306523e-05 9.366266e-01 9.819288e-01 12 89591103 89591295 193 - 2.136 2.141 0.015
ENSG00000070961 E006 0.1268540 1.238007e-02 2.679342e-02   12 89598590 89598591 2 - 0.000 0.238 12.380
ENSG00000070961 E007 0.6168311 1.436416e-02 6.149277e-03 5.750912e-02 12 89598592 89598656 65 - 0.066 0.504 3.738
ENSG00000070961 E008 0.7433381 1.398583e-02 8.950311e-04 1.377250e-02 12 89598657 89598743 87 - 0.066 0.593 4.153
ENSG00000070961 E009 194.7214663 1.004018e-04 1.686412e-01 4.399529e-01 12 89599117 89599299 183 - 2.091 2.043 -0.158
ENSG00000070961 E010 85.5577793 3.402145e-04 6.145729e-01 8.325933e-01 12 89601326 89601403 78 - 1.736 1.711 -0.085
ENSG00000070961 E011 55.6391478 2.974205e-03 9.487189e-01 9.867620e-01 12 89601404 89601433 30 - 1.551 1.548 -0.010
ENSG00000070961 E012 180.1112352 1.001991e-04 1.686250e-02 1.132581e-01 12 89603043 89603254 212 - 2.061 1.972 -0.299
ENSG00000070961 E013 7.6149525 2.802518e-03 7.944932e-07 3.788700e-05 12 89603255 89603711 457 - 0.648 1.213 2.153
ENSG00000070961 E014 96.3645773 1.530341e-04 4.567307e-01 7.289927e-01 12 89603712 89603795 84 - 1.788 1.752 -0.121
ENSG00000070961 E015 68.4067910 1.981562e-04 5.230602e-01 7.765561e-01 12 89603796 89603837 42 - 1.634 1.672 0.130
ENSG00000070961 E016 93.3447532 1.579633e-04 9.664541e-01 9.932022e-01 12 89603838 89603925 88 - 1.770 1.774 0.013
ENSG00000070961 E017 3.4824932 1.572894e-02 3.480796e-02 1.783183e-01 12 89603926 89604154 229 - 0.448 0.786 1.501
ENSG00000070961 E018 136.2031306 1.564446e-04 5.674919e-01 8.053018e-01 12 89604155 89604346 192 - 1.929 1.955 0.085
ENSG00000070961 E019 87.7259633 7.608302e-04 8.912581e-01 9.637844e-01 12 89609937 89610043 107 - 1.743 1.752 0.030
ENSG00000070961 E020 91.0299774 1.634520e-04 6.521730e-01 8.534713e-01 12 89610421 89610508 88 - 1.762 1.740 -0.072
ENSG00000070961 E021 2.3277630 1.843981e-01 9.642948e-04 1.459677e-02 12 89610509 89610705 197 - 0.261 0.879 2.999
ENSG00000070961 E022 163.6017683 1.555899e-04 4.828779e-01 7.476733e-01 12 89611193 89611372 180 - 2.014 1.988 -0.085
ENSG00000070961 E023 4.7123085 6.036301e-02 9.393052e-04 1.431087e-02 12 89611373 89612147 775 - 0.496 1.021 2.153
ENSG00000070961 E024 158.7031372 1.485235e-04 2.435757e-01 5.335911e-01 12 89616802 89617039 238 - 2.002 1.958 -0.149
ENSG00000070961 E025 119.9914098 3.602422e-04 1.519368e-01 4.156088e-01 12 89619999 89620240 242 - 1.884 1.819 -0.219
ENSG00000070961 E026 103.6835888 1.545727e-04 1.467566e-01 4.078163e-01 12 89621549 89621791 243 - 1.822 1.752 -0.238
ENSG00000070961 E027 101.5969883 1.630561e-04 1.897017e-02 1.226404e-01 12 89624183 89624397 215 - 1.818 1.698 -0.405
ENSG00000070961 E028 107.3336711 2.682361e-04 8.582677e-01 9.505500e-01 12 89626454 89626615 162 - 1.831 1.824 -0.022
ENSG00000070961 E029 51.7152015 3.048378e-04 8.906368e-01 9.636029e-01 12 89627678 89627716 39 - 1.519 1.530 0.037
ENSG00000070961 E030 39.6887196 3.411488e-04 5.961651e-01 8.224892e-01 12 89630505 89630515 11 - 1.413 1.373 -0.136
ENSG00000070961 E031 84.9210314 2.903749e-04 4.108832e-01 6.926382e-01 12 89630516 89630645 130 - 1.735 1.692 -0.145
ENSG00000070961 E032 83.8383164 1.859249e-04 8.541569e-01 9.485068e-01 12 89634778 89634903 126 - 1.723 1.735 0.039
ENSG00000070961 E033 123.1601872 1.375256e-04 6.671827e-01 8.615259e-01 12 89634997 89635251 255 - 1.891 1.873 -0.058
ENSG00000070961 E034 0.3543453 1.577466e-02 1.000000e+00   12 89641823 89642157 335 - 0.096 0.000 -10.732
ENSG00000070961 E035 76.4560467 1.876755e-04 1.266754e-01 3.772979e-01 12 89642158 89642355 198 - 1.694 1.607 -0.297
ENSG00000070961 E036 113.9277917 1.308793e-04 8.724641e-03 7.332940e-02 12 89655679 89656107 429 - 1.868 1.740 -0.429
ENSG00000070961 E037 0.7070564 2.166007e-02 1.000000e+00 1.000000e+00 12 89662989 89663091 103 - 0.174 0.000 -11.549
ENSG00000070961 E038 0.9487969 2.716173e-01 7.532513e-01 9.028971e-01 12 89666222 89666361 140 - 0.197 0.238 0.348
ENSG00000070961 E039 1.2184927 1.549373e-02 1.428563e-02 1.015930e-01 12 89667603 89667771 169 - 0.174 0.593 2.568
ENSG00000070961 E040 1.7860785 1.928726e-02 6.967499e-01 8.762010e-01 12 89677622 89677807 186 - 0.315 0.391 0.452
ENSG00000070961 E041 1.0620283 1.115324e-02 4.939682e-01 7.557112e-01 12 89708394 89708595 202 - 0.240 0.000 -12.452
ENSG00000070961 E042 24.5110545 5.497995e-04 5.297486e-03 5.171907e-02 12 89708596 89708838 243 - 1.235 0.919 -1.147
ENSG00000070961 E043 0.0000000       12 89709219 89709368 150 -      

Help

Please Click HERE to learn more details about the results from DEXseq.