ENSG00000071189

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000409076 ENSG00000071189 No_inf pgKDN_inf SNX13 protein_coding nonsense_mediated_decay 12.20648 8.873789 16.46857 0.5232394 0.6960606 0.8913445 2.2567345 0.0000000 3.7607041 0.0000000 0.7495750 8.55869012 0.16400000 0.000000 0.227075 0.227075 8.731526e-05 8.731526e-05 FALSE TRUE
ENST00000428135 ENSG00000071189 No_inf pgKDN_inf SNX13 protein_coding protein_coding 12.20648 8.873789 16.46857 0.5232394 0.6960606 0.8913445 5.5231219 4.5748926 6.4216777 0.5945456 0.3459246 0.48830717 0.47312500 0.532275 0.392175 -0.140100 7.568290e-01 8.731526e-05 FALSE TRUE
ENST00000496855 ENSG00000071189 No_inf pgKDN_inf SNX13 protein_coding protein_coding_CDS_not_defined 12.20648 8.873789 16.46857 0.5232394 0.6960606 0.8913445 2.5416924 1.8686130 4.3261029 0.8001796 0.8558386 1.20673106 0.19505833 0.196325 0.260425 0.064100 8.380412e-01 8.731526e-05 FALSE TRUE
ENST00000611725 ENSG00000071189 No_inf pgKDN_inf SNX13 protein_coding protein_coding 12.20648 8.873789 16.46857 0.5232394 0.6960606 0.8913445 0.9674223 1.0573526 1.0069278 0.1793752 0.2138128 -0.06981956 0.08573333 0.120250 0.062275 -0.057975 7.223157e-01 8.731526e-05 FALSE TRUE
MSTRG.25865.2 ENSG00000071189 No_inf pgKDN_inf SNX13 protein_coding   12.20648 8.873789 16.46857 0.5232394 0.6960606 0.8913445 0.4632493 0.8698691 0.5198787 0.5868886 0.3003690 -0.73162670 0.04140833 0.092375 0.031850 -0.060525 8.627719e-01 8.731526e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000071189 E001 0.8412710 0.0298587145 5.628812e-01 8.025277e-01 7 17790761 17790835 75 - 0.298 0.206 -0.696
ENSG00000071189 E002 55.0911972 0.0002691241 1.515273e-13 2.208777e-11 7 17790836 17792841 2006 - 1.604 1.885 0.949
ENSG00000071189 E003 30.5048987 0.0015504082 7.689200e-01 9.106268e-01 7 17792842 17793419 578 - 1.485 1.501 0.055
ENSG00000071189 E004 29.3715821 0.0038030012 6.025836e-01 8.265757e-01 7 17793420 17793763 344 - 1.488 1.457 -0.105
ENSG00000071189 E005 47.7660116 0.0026827009 7.973934e-01 9.234862e-01 7 17793764 17794292 529 - 1.677 1.688 0.037
ENSG00000071189 E006 12.7165592 0.0029944354 4.867383e-06 1.840936e-04 7 17794293 17796826 2534 - 0.939 1.311 1.340
ENSG00000071189 E007 13.3595954 0.0492533361 7.857317e-01 9.174837e-01 7 17796827 17796939 113 - 1.158 1.139 -0.069
ENSG00000071189 E008 0.4911106 0.0158048931 6.682951e-01   7 17798659 17798689 31 - 0.144 0.206 0.625
ENSG00000071189 E009 9.6066600 0.0015213688 3.189006e-03 3.613721e-02 7 17798690 17798758 69 - 1.115 0.831 -1.058
ENSG00000071189 E010 13.5172538 0.0010444755 4.719281e-02 2.133884e-01 7 17799009 17799154 146 - 1.214 1.054 -0.573
ENSG00000071189 E011 9.3720578 0.0023964218 6.938343e-01 8.748950e-01 7 17801588 17801659 72 - 0.994 1.031 0.133
ENSG00000071189 E012 13.0047579 0.0013313398 9.854081e-01 9.989951e-01 7 17803419 17803580 162 - 1.140 1.139 -0.005
ENSG00000071189 E013 8.6875645 0.0023354926 7.402728e-02 2.772204e-01 7 17814834 17814944 111 - 1.043 0.868 -0.655
ENSG00000071189 E014 4.8200893 0.0029935621 1.199574e-01 3.661035e-01 7 17816182 17816219 38 - 0.827 0.638 -0.773
ENSG00000071189 E015 6.5138087 0.0038932527 1.441078e-01 4.043234e-01 7 17816220 17816289 70 - 0.929 0.768 -0.623
ENSG00000071189 E016 9.4113162 0.0039178766 1.241948e-01 3.734082e-01 7 17821509 17821648 140 - 1.066 0.919 -0.545
ENSG00000071189 E017 0.9668992 0.1952183185 9.810929e-01 9.980434e-01 7 17821649 17821681 33 - 0.298 0.282 -0.109
ENSG00000071189 E018 0.0000000       7 17821682 17821697 16 -      
ENSG00000071189 E019 7.0077543 0.0030214668 3.052928e-01 5.985990e-01 7 17826022 17826091 70 - 0.939 0.831 -0.412
ENSG00000071189 E020 4.6194858 0.0040272986 9.857415e-01 9.990789e-01 7 17830010 17830047 38 - 0.743 0.745 0.009
ENSG00000071189 E021 9.3854862 0.0019619244 5.318328e-01 7.823639e-01 7 17834052 17834184 133 - 0.985 1.043 0.210
ENSG00000071189 E022 7.0727926 0.0045219616 4.037502e-01 6.865892e-01 7 17834761 17834865 105 - 0.864 0.950 0.326
ENSG00000071189 E023 10.4382245 0.0013328191 8.556776e-01 9.491808e-01 7 17839807 17840000 194 - 1.059 1.043 -0.058
ENSG00000071189 E024 7.6067737 0.0024525737 1.325662e-01 3.864772e-01 7 17845595 17845694 100 - 0.985 0.831 -0.586
ENSG00000071189 E025 9.7572161 0.0015350895 2.171190e-02 1.336702e-01 7 17850347 17850435 89 - 1.101 0.886 -0.798
ENSG00000071189 E026 11.2422867 0.0150982975 1.461172e-01 4.070823e-01 7 17850826 17850964 139 - 1.134 0.992 -0.517
ENSG00000071189 E027 0.1265070 0.0122515919 3.428200e-01   7 17868282 17868406 125 - 0.000 0.115 10.687
ENSG00000071189 E028 4.9390857 0.0069820123 1.007973e-01 3.314071e-01 7 17868407 17868490 84 - 0.840 0.638 -0.822
ENSG00000071189 E029 4.8309783 0.0112924709 3.914028e-01 6.765670e-01 7 17873528 17873616 89 - 0.801 0.695 -0.429
ENSG00000071189 E030 3.8558657 0.0061204681 1.917556e-01 4.714778e-01 7 17875480 17875556 77 - 0.743 0.572 -0.728
ENSG00000071189 E031 3.3946320 0.0043740298 6.952163e-01 8.755454e-01 7 17875557 17875581 25 - 0.658 0.606 -0.223
ENSG00000071189 E032 7.4053717 0.0041888464 8.012975e-01 9.258872e-01 7 17875669 17875790 122 - 0.929 0.903 -0.099
ENSG00000071189 E033 2.2826218 0.0084765123 9.380820e-02 3.185050e-01 7 17879427 17882943 3517 - 0.597 0.346 -1.282
ENSG00000071189 E034 0.0000000       7 17888156 17888559 404 -      
ENSG00000071189 E035 0.0000000       7 17888560 17888722 163 -      
ENSG00000071189 E036 0.4919310 0.4288834534 7.308705e-01   7 17888723 17890362 1640 - 0.144 0.206 0.624
ENSG00000071189 E037 8.0224512 0.0017855216 9.912548e-01 1.000000e+00 7 17890363 17890484 122 - 0.949 0.950 0.004
ENSG00000071189 E038 3.1576278 0.0044368551 9.288397e-01 9.789546e-01 7 17891546 17891561 16 - 0.618 0.606 -0.053
ENSG00000071189 E039 5.4621180 0.0434167647 8.959628e-01 9.657809e-01 7 17891562 17891628 67 - 0.814 0.790 -0.095
ENSG00000071189 E040 3.1447850 0.1439556965 6.931803e-01 8.746998e-01 7 17891629 17891635 7 - 0.638 0.572 -0.293
ENSG00000071189 E041 3.7542540 0.0214396311 6.721093e-01 8.641091e-01 7 17893332 17893347 16 - 0.694 0.638 -0.237
ENSG00000071189 E042 6.2850183 0.0152122320 3.463801e-01 6.371862e-01 7 17893348 17893434 87 - 0.898 0.790 -0.417
ENSG00000071189 E043 5.9264282 0.0024385117 3.359826e-01 6.278459e-01 7 17897334 17897446 113 - 0.875 0.768 -0.419
ENSG00000071189 E044 0.0000000       7 17897844 17897884 41 -      
ENSG00000071189 E045 0.0000000       7 17898217 17898300 84 -      
ENSG00000071189 E046 0.1271363 0.0124730269 3.425337e-01   7 17898827 17898973 147 - 0.000 0.115 10.687
ENSG00000071189 E047 0.3709916 0.0165833152 3.497998e-01   7 17898974 17900106 1133 - 0.078 0.206 1.625
ENSG00000071189 E048 0.0000000       7 17900124 17900248 125 -      
ENSG00000071189 E049 0.2459655 0.0163536514 7.361433e-01   7 17907249 17907340 92 - 0.078 0.115 0.625
ENSG00000071189 E050 6.1638602 0.0046001508 2.490489e-01 5.399229e-01 7 17940284 17940501 218 - 0.898 0.768 -0.504

Help

Please Click HERE to learn more details about the results from DEXseq.