ENSG00000071889

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000322269 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding protein_coding 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 1.9132156 2.443491 0.9741515 1.22729097 0.97415149 -1.3178835 0.08825833 0.122175 0.045775 -0.076400 0.50114010 0.03068762 FALSE  
ENST00000359889 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding protein_coding 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 4.9556732 2.440853 6.3934512 1.45591603 2.36263496 1.3855655 0.22176667 0.116050 0.288575 0.172525 0.70208621 0.03068762 FALSE  
ENST00000369643 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding protein_coding 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 0.4398695 1.319608 0.0000000 1.31960836 0.00000000 -7.0548575 0.02112500 0.063375 0.000000 -0.063375 0.85169065 0.03068762 FALSE  
ENST00000434658 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding nonsense_mediated_decay 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 0.4911735 0.000000 1.4735204 0.00000000 1.47352044 7.2128810 0.02743333 0.000000 0.082300 0.082300 0.84927472 0.03068762 FALSE  
ENST00000440318 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding nonsense_mediated_decay 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 1.6026644 2.143833 0.8566680 0.60677899 0.30532817 -1.3133553 0.07491667 0.099850 0.040350 -0.059500 0.54817488 0.03068762 FALSE  
ENST00000442929 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding protein_coding 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 1.0580320 0.000000 2.4629928 0.00000000 1.47856746 7.9501142 0.04330000 0.000000 0.101475 0.101475 0.43568679 0.03068762 TRUE  
ENST00000447601 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding protein_coding 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 4.2628668 5.210425 3.6531675 1.84292471 2.73595824 -0.5110754 0.22010000 0.257425 0.199500 -0.057925 0.81344085 0.03068762 FALSE  
ENST00000475657 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding retained_intron 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 1.3472412 2.206950 1.1156836 0.83169864 0.42641654 -0.9777751 0.06271667 0.098775 0.053225 -0.045550 0.85935086 0.03068762    
ENST00000612856 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding retained_intron 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 0.6574473 1.344799 0.1792125 0.01442704 0.03468999 -2.8399992 0.03179167 0.066275 0.008550 -0.057725 0.03068762 0.03068762 FALSE  
ENST00000621967 ENSG00000071889 No_inf pgKDN_inf FAM3A protein_coding nonsense_mediated_decay 21.24571 20.87436 21.09685 1.951962 2.034675 0.01528819 2.2565404 2.225614 1.6732454 2.22561409 1.03147566 -0.4094257 0.10773333 0.106900 0.072900 -0.034000 0.82452906 0.03068762 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000071889 E001 0.4702767 0.0156153872 3.318828e-02   X 154506159 154506159 1 - 0.311 0.000 -13.057
ENSG00000071889 E002 0.4702767 0.0156153872 3.318828e-02   X 154506160 154506170 11 - 0.311 0.000 -13.058
ENSG00000071889 E003 0.4702767 0.0156153872 3.318828e-02   X 154506171 154506172 2 - 0.311 0.000 -13.058
ENSG00000071889 E004 2.5625506 0.0060080928 6.123393e-01 8.313633e-01 X 154506173 154506203 31 - 0.588 0.517 -0.328
ENSG00000071889 E005 31.5148507 0.0015856304 8.274412e-01 9.375268e-01 X 154506204 154506534 331 - 1.517 1.504 -0.044
ENSG00000071889 E006 16.8266143 0.0008635748 8.541043e-01 9.485068e-01 X 154506535 154506639 105 - 1.242 1.254 0.042
ENSG00000071889 E007 11.4013749 0.0052786333 7.481434e-01 9.006275e-01 X 154506640 154506710 71 - 1.106 1.079 -0.097
ENSG00000071889 E008 24.9480980 0.0036495718 4.996978e-01 7.599204e-01 X 154506711 154506906 196 - 1.390 1.430 0.138
ENSG00000071889 E009 10.9703279 0.0014321848 2.272185e-01 5.155574e-01 X 154507203 154507246 44 - 1.018 1.119 0.368
ENSG00000071889 E010 11.7414855 0.0062225565 5.975519e-02 2.451758e-01 X 154507247 154507329 83 - 1.006 1.169 0.588
ENSG00000071889 E011 0.3706447 0.2151066863 7.090798e-01   X 154507330 154507405 76 - 0.101 0.164 0.809
ENSG00000071889 E012 15.1727640 0.0009873921 3.609559e-01 6.505544e-01 X 154507406 154507490 85 - 1.242 1.175 -0.237
ENSG00000071889 E013 2.5924193 0.0068140227 4.291652e-01 7.075845e-01 X 154507491 154507591 101 - 0.490 0.600 0.510
ENSG00000071889 E014 1.9968617 0.0072215224 7.612929e-02 2.819251e-01 X 154507680 154507810 131 - 0.311 0.574 1.395
ENSG00000071889 E015 10.3784111 0.0013826699 1.722736e-01 4.449479e-01 X 154507811 154507861 51 - 1.115 0.997 -0.428
ENSG00000071889 E016 1.3432057 0.0095009382 6.087591e-01 8.297053e-01 X 154507862 154507882 21 - 0.410 0.332 -0.453
ENSG00000071889 E017 7.0955813 0.0035351668 4.527897e-01 7.257500e-01 X 154508289 154508315 27 - 0.947 0.870 -0.290
ENSG00000071889 E018 7.2157653 0.0033095707 3.769940e-01 6.641424e-01 X 154508316 154508347 32 - 0.959 0.870 -0.337
ENSG00000071889 E019 0.2533610 0.0161144199 2.905761e-01   X 154508453 154508473 21 - 0.000 0.164 11.572
ENSG00000071889 E020 14.1697534 0.0014692871 3.710286e-01 6.590824e-01 X 154508474 154508571 98 - 1.140 1.207 0.239
ENSG00000071889 E021 9.3356181 0.0018663419 9.031242e-01 9.688647e-01 X 154508572 154508597 26 - 1.006 1.017 0.038
ENSG00000071889 E022 1.3805313 0.0097629669 4.914157e-02 2.185842e-01 X 154508598 154508652 55 - 0.183 0.486 1.980
ENSG00000071889 E023 0.8801057 0.0130406015 7.188592e-02 2.719814e-01 X 154508653 154508768 116 - 0.101 0.376 2.395
ENSG00000071889 E024 0.3724075 0.0166052111 6.682773e-01   X 154508769 154508811 43 - 0.101 0.164 0.810
ENSG00000071889 E025 9.6812540 0.0014957368 1.940542e-10 1.872327e-08 X 154508812 154511412 2601 - 0.558 1.214 2.554
ENSG00000071889 E026 8.5182584 0.0044469116 5.222564e-02 2.269367e-01 X 154511848 154511867 20 - 1.069 0.883 -0.690
ENSG00000071889 E027 8.1213914 0.0019368328 4.153866e-03 4.363744e-02 X 154511868 154511871 4 - 1.088 0.813 -1.032
ENSG00000071889 E028 3.8893554 0.0039268911 1.564405e-01 4.226762e-01 X 154512314 154512411 98 - 0.776 0.600 -0.738
ENSG00000071889 E029 0.0000000       X 154512412 154512431 20 -      
ENSG00000071889 E030 15.9004661 0.0019405994 2.016685e-01 4.840392e-01 X 154512823 154512936 114 - 1.274 1.182 -0.324
ENSG00000071889 E031 9.5784701 0.0209435388 7.524259e-01 9.024593e-01 X 154515760 154515812 53 - 1.006 1.036 0.107
ENSG00000071889 E032 6.7351786 0.0031859847 7.326013e-01 8.937031e-01 X 154515813 154515909 97 - 0.906 0.870 -0.138
ENSG00000071889 E033 7.5847093 0.0021103110 4.443199e-01 7.189743e-01 X 154515910 154515968 59 - 0.972 0.896 -0.283
ENSG00000071889 E034 13.2443259 0.0018474884 7.703955e-01 9.115029e-01 X 154515969 154516249 281 - 1.164 1.141 -0.083

Help

Please Click HERE to learn more details about the results from DEXseq.