ENSG00000073792

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000346192 ENSG00000073792 No_inf pgKDN_inf IGF2BP2 protein_coding protein_coding 32.8249 55.82321 19.94965 2.487586 0.7042294 -1.484037 10.682313 17.733708 7.211912 1.7232836 1.3723139 -1.29685491 0.33101667 0.320525 0.359150 0.038625 9.049319e-01 3.575362e-10 FALSE TRUE
ENST00000382199 ENSG00000073792 No_inf pgKDN_inf IGF2BP2 protein_coding protein_coding 32.8249 55.82321 19.94965 2.487586 0.7042294 -1.484037 1.898340 1.038481 3.290906 1.0384808 1.1586521 1.65456147 0.08515833 0.019000 0.170275 0.151275 1.659166e-01 3.575362e-10 FALSE TRUE
ENST00000457616 ENSG00000073792 No_inf pgKDN_inf IGF2BP2 protein_coding protein_coding 32.8249 55.82321 19.94965 2.487586 0.7042294 -1.484037 4.839499 4.764133 4.563966 1.7806749 1.5729551 -0.06179299 0.18112500 0.084250 0.229450 0.145200 5.751354e-01 3.575362e-10 FALSE TRUE
ENST00000464166 ENSG00000073792 No_inf pgKDN_inf IGF2BP2 protein_coding protein_coding_CDS_not_defined 32.8249 55.82321 19.94965 2.487586 0.7042294 -1.484037 5.099679 11.171444 0.000000 0.9046053 0.0000000 -10.12689079 0.12703333 0.201225 0.000000 -0.201225 3.575362e-10 3.575362e-10 FALSE FALSE
MSTRG.21223.3 ENSG00000073792 No_inf pgKDN_inf IGF2BP2 protein_coding   32.8249 55.82321 19.94965 2.487586 0.7042294 -1.484037 6.292199 11.436144 3.833867 1.1734145 0.9332312 -1.57423127 0.18342500 0.203700 0.190425 -0.013275 9.277704e-01 3.575362e-10 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000073792 E001 0.1272623 0.0123620620 1.000000e+00   3 185643121 185643129 9 - 0.000 0.067 9.648
ENSG00000073792 E002 0.7538164 0.0507595089 4.402877e-01 0.7160554197 3 185643130 185643267 138 - 0.134 0.262 1.194
ENSG00000073792 E003 29.6926569 0.0004893120 6.886014e-01 0.8717611607 3 185643268 185643974 707 - 1.432 1.457 0.086
ENSG00000073792 E004 231.3384914 0.0001369890 2.117003e-01 0.4967304160 3 185643975 185645500 1526 - 2.311 2.335 0.079
ENSG00000073792 E005 24.1620066 0.0299253456 3.732259e-01 0.6609610236 3 185645501 185645623 123 - 1.305 1.386 0.284
ENSG00000073792 E006 5.3235652 0.0028077562 1.344219e-06 0.0000602152 3 185646880 185647024 145 - 0.134 0.891 4.230
ENSG00000073792 E007 23.3806323 0.0008627515 4.388095e-01 0.7148607075 3 185647025 185647138 114 - 1.313 1.365 0.184
ENSG00000073792 E008 26.6091808 0.0005540050 4.530278e-01 0.7258936220 3 185649403 185649534 132 - 1.370 1.418 0.166
ENSG00000073792 E009 15.5190553 0.0009128547 5.261207e-03 0.0515080651 3 185652094 185652168 75 - 1.002 1.240 0.858
ENSG00000073792 E010 1.2702003 0.0109397860 1.472292e-02 0.1037317087 3 185652531 185652587 57 - 0.000 0.424 14.789
ENSG00000073792 E011 22.1420044 0.0006260696 3.464795e-01 0.6371922405 3 185657286 185657402 117 - 1.281 1.346 0.228
ENSG00000073792 E012 15.4380924 0.0010995429 1.357623e-01 0.3916663376 3 185658341 185658409 69 - 1.255 1.144 -0.397
ENSG00000073792 E013 14.6846662 0.0011139978 5.956698e-02 0.2447387261 3 185672541 185672669 129 - 1.255 1.111 -0.512
ENSG00000073792 E014 2.5276256 0.0066265830 3.650971e-03 0.0398686934 3 185675016 185675295 280 - 0.134 0.618 3.120
ENSG00000073792 E015 28.3040842 0.0117575162 2.068696e-03 0.0262145747 3 185675296 185675431 136 - 1.566 1.356 -0.724
ENSG00000073792 E016 22.3770866 0.0019038322 1.451807e-01 0.4054774437 3 185675791 185675913 123 - 1.396 1.302 -0.327
ENSG00000073792 E017 21.4712202 0.0006476310 8.899889e-01 0.9632795925 3 185687057 185687191 135 - 1.320 1.313 -0.026
ENSG00000073792 E018 0.0000000       3 185689108 185689354 247 -      
ENSG00000073792 E019 20.7644509 0.0010486364 4.713584e-01 0.7387131291 3 185689355 185689454 100 - 1.264 1.316 0.182
ENSG00000073792 E020 16.3488918 0.0015745464 6.207898e-01 0.8361221350 3 185689455 185689554 100 - 1.228 1.192 -0.128
ENSG00000073792 E021 15.8704897 0.0009243711 7.148826e-01 0.8850939956 3 185689555 185689627 73 - 1.209 1.183 -0.094
ENSG00000073792 E022 16.0653539 0.0008874542 2.990944e-01 0.5919546695 3 185692699 185692762 64 - 1.136 1.219 0.298
ENSG00000073792 E023 0.7264745 0.1252732015 1.090668e-01 0.3466992135 3 185692763 185692780 18 - 0.389 0.124 -2.128
ENSG00000073792 E024 1.4892902 0.0177964593 8.810812e-01 0.9600390910 3 185693177 185693228 52 - 0.389 0.366 -0.128
ENSG00000073792 E025 0.1186381 0.0118396356 2.278206e-01   3 185696415 185696611 197 - 0.134 0.000 -13.902
ENSG00000073792 E026 12.8946528 0.0011259782 7.623791e-01 0.9073018056 3 185696612 185696663 52 - 1.124 1.100 -0.086
ENSG00000073792 E027 10.6043370 0.0012870371 6.723828e-02 0.2615150708 3 185698299 185698347 49 - 1.136 0.975 -0.585
ENSG00000073792 E028 0.2533610 0.0159972720 6.652332e-01   3 185814055 185814100 46 - 0.000 0.124 12.618
ENSG00000073792 E029 0.1265070 0.0123016448 1.000000e+00   3 185821012 185821131 120 - 0.000 0.067 11.670
ENSG00000073792 E030 8.9895798 0.0015384755 4.618369e-02 0.2107560004 3 185823153 185823213 61 - 1.087 0.901 -0.690
ENSG00000073792 E031 0.2545247 0.2571581043 7.326239e-01   3 185823214 185823271 58 - 0.000 0.124 12.033
ENSG00000073792 E032 17.3929726 0.0008902787 2.215532e-02 0.1352796633 3 185824783 185825042 260 - 1.335 1.173 -0.568

Help

Please Click HERE to learn more details about the results from DEXseq.