ENSG00000073921

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000393346 ENSG00000073921 No_inf pgKDN_inf PICALM protein_coding protein_coding 119.6171 127.7699 127.1899 2.201049 2.99883 -0.006562933 11.189154 10.387849 15.266361 1.6483541 1.1274996 0.5550158 0.09224167 0.081200 0.119975 0.038775 0.538382228 0.002462223 FALSE  
ENST00000526548 ENSG00000073921 No_inf pgKDN_inf PICALM protein_coding retained_intron 119.6171 127.7699 127.1899 2.201049 2.99883 -0.006562933 10.033158 14.832783 6.823111 1.8660296 1.7904601 -1.1191471 0.08362500 0.116400 0.052925 -0.063475 0.269459604 0.002462223    
ENST00000526907 ENSG00000073921 No_inf pgKDN_inf PICALM protein_coding retained_intron 119.6171 127.7699 127.1899 2.201049 2.99883 -0.006562933 6.248978 10.761913 2.902885 0.8145029 0.2931741 -1.8867536 0.05185000 0.084000 0.022825 -0.061175 0.002462223 0.002462223    
MSTRG.5358.6 ENSG00000073921 No_inf pgKDN_inf PICALM protein_coding   119.6171 127.7699 127.1899 2.201049 2.99883 -0.006562933 8.098190 9.613977 7.463893 1.8935226 1.2018686 -0.3647733 0.06762500 0.075050 0.058375 -0.016675 0.855185736 0.002462223 FALSE  
MSTRG.5358.8 ENSG00000073921 No_inf pgKDN_inf PICALM protein_coding   119.6171 127.7699 127.1899 2.201049 2.99883 -0.006562933 36.957190 39.459345 42.471259 3.8534824 5.9668108 0.1060939 0.30763333 0.308925 0.334850 0.025925 0.918221110 0.002462223 FALSE  
MSTRG.5358.9 ENSG00000073921 No_inf pgKDN_inf PICALM protein_coding   119.6171 127.7699 127.1899 2.201049 2.99883 -0.006562933 35.794453 31.451640 43.801967 1.1332854 5.5786151 0.4777311 0.29947500 0.246100 0.344850 0.098750 0.426577008 0.002462223 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000073921 E001 0.1268540 1.235395e-02 5.338221e-01   11 85957121 85957174 54 - 0.000 0.095 9.687
ENSG00000073921 E002 0.1268540 1.235395e-02 5.338221e-01   11 85957175 85957180 6 - 0.000 0.095 12.121
ENSG00000073921 E003 0.6070457 2.532324e-02 6.638590e-01 8.601709e-01 11 85957181 85957218 38 - 0.239 0.173 -0.577
ENSG00000073921 E004 22.7471727 2.118918e-03 7.138329e-01 8.847290e-01 11 85957219 85957683 465 - 1.388 1.363 -0.086
ENSG00000073921 E005 6.8249212 1.156388e-02 4.663484e-01 7.350741e-01 11 85957684 85957687 4 - 0.933 0.853 -0.303
ENSG00000073921 E006 673.2336866 5.234539e-05 7.296363e-04 1.172592e-02 11 85957688 85958754 1067 - 2.810 2.845 0.116
ENSG00000073921 E007 106.1206832 1.436122e-04 5.969783e-01 8.230005e-01 11 85958755 85958810 56 - 2.022 2.036 0.047
ENSG00000073921 E008 66.9661724 2.173007e-04 9.059617e-01 9.700033e-01 11 85958811 85958816 6 - 1.835 1.829 -0.019
ENSG00000073921 E009 57.7769275 2.563571e-04 8.517031e-01 9.475727e-01 11 85958817 85958817 1 - 1.773 1.765 -0.029
ENSG00000073921 E010 77.5676404 1.981306e-04 6.465200e-01 8.503871e-01 11 85958818 85958838 21 - 1.887 1.902 0.048
ENSG00000073921 E011 88.6399535 6.298536e-04 8.548629e-01 9.488234e-01 11 85958839 85958882 44 - 1.956 1.949 -0.025
ENSG00000073921 E012 139.9336493 2.820006e-03 3.462463e-01 6.370827e-01 11 85958883 85958986 104 - 2.133 2.163 0.101
ENSG00000073921 E013 81.0580160 6.078273e-04 4.582157e-01 7.301506e-01 11 85958987 85959022 36 - 1.901 1.925 0.082
ENSG00000073921 E014 57.1978557 3.045512e-04 2.339352e-01 5.230058e-01 11 85959023 85959036 14 - 1.740 1.786 0.156
ENSG00000073921 E015 65.1116757 3.840397e-03 6.188438e-01 8.352033e-01 11 85959037 85959060 24 - 1.832 1.808 -0.080
ENSG00000073921 E016 1.4773930 9.203974e-03 5.586488e-01 8.001925e-01 11 85960675 85960777 103 - 0.346 0.434 0.493
ENSG00000073921 E017 99.3750640 6.820178e-04 7.786386e-01 9.149258e-01 11 85974708 85974781 74 - 1.997 2.005 0.025
ENSG00000073921 E018 64.6441184 8.424041e-04 3.318666e-01 6.240027e-01 11 85974782 85974812 31 - 1.798 1.834 0.122
ENSG00000073921 E019 50.4408303 2.047487e-03 2.289669e-01 5.177073e-01 11 85976623 85976648 26 - 1.682 1.736 0.183
ENSG00000073921 E020 54.6827326 6.611174e-04 3.858317e-02 1.899655e-01 11 85976649 85976682 34 - 1.700 1.784 0.287
ENSG00000073921 E021 16.0638613 8.834401e-04 1.289815e-07 7.353584e-06 11 85976683 85977005 323 - 0.980 1.381 1.433
ENSG00000073921 E022 33.2324357 4.109907e-04 4.662348e-01 7.349998e-01 11 85978070 85978093 24 - 1.515 1.551 0.125
ENSG00000073921 E023 6.8140329 2.023852e-03 2.075624e-02 1.298098e-01 11 85978094 85978150 57 - 0.751 0.993 0.929
ENSG00000073921 E024 19.9193886 6.735937e-04 4.579696e-16 8.546759e-14 11 85978151 85978715 565 - 0.920 1.514 2.112
ENSG00000073921 E025 66.9820890 6.290700e-04 2.709237e-02 1.529892e-01 11 85981129 85981183 55 - 1.787 1.870 0.278
ENSG00000073921 E026 62.1719615 1.525713e-03 4.873759e-01 7.509013e-01 11 85981184 85981228 45 - 1.786 1.813 0.093
ENSG00000073921 E027 52.1700837 1.469051e-03 2.254979e-01 5.133073e-01 11 85981745 85981775 31 - 1.697 1.750 0.177
ENSG00000073921 E028 99.4268709 3.659405e-03 8.113535e-01 9.305245e-01 11 85981872 85981988 117 - 2.007 1.996 -0.035
ENSG00000073921 E029 26.4791654 5.411662e-04 7.426824e-01 8.983275e-01 11 85981989 85982003 15 - 1.429 1.447 0.061
ENSG00000073921 E030 0.7239174 4.150518e-02 4.284329e-01 7.069278e-01 11 85982004 85982185 182 - 0.296 0.173 -0.993
ENSG00000073921 E031 85.8800981 3.393217e-03 5.249030e-01 7.778371e-01 11 85983866 85983973 108 - 1.952 1.925 -0.091
ENSG00000073921 E032 17.0082761 7.914060e-04 8.380296e-01 9.420044e-01 11 85990250 85990378 129 - 1.263 1.248 -0.055
ENSG00000073921 E033 5.8092156 3.128874e-02 1.012474e-01 3.322845e-01 11 85990379 85990399 21 - 0.712 0.922 0.827
ENSG00000073921 E034 66.1651012 7.347577e-03 6.435062e-01 8.488649e-01 11 85996826 85996929 104 - 1.840 1.815 -0.083
ENSG00000073921 E035 43.4723607 3.817498e-04 6.790988e-03 6.182733e-02 11 86000643 86000680 38 - 1.708 1.583 -0.424
ENSG00000073921 E036 70.3880658 9.643656e-04 3.073341e-02 1.649658e-01 11 86000681 86000779 99 - 1.894 1.812 -0.279
ENSG00000073921 E037 0.2362687 1.569195e-02 2.452990e-01   11 86001031 86001034 4 - 0.173 0.000 -13.805
ENSG00000073921 E038 76.8533502 2.045382e-04 1.709289e-01 4.433219e-01 11 86001035 86001158 124 - 1.915 1.867 -0.162
ENSG00000073921 E039 66.3564401 2.629865e-04 1.621956e-01 4.306568e-01 11 86003366 86003451 86 - 1.855 1.802 -0.179
ENSG00000073921 E040 0.8798202 2.216791e-02 5.047228e-02 2.220188e-01 11 86003452 86003778 327 - 0.095 0.393 2.592
ENSG00000073921 E041 0.4692693 5.331321e-02 5.032575e-02   11 86007369 86007541 173 - 0.296 0.000 -14.345
ENSG00000073921 E042 47.9559105 9.825468e-04 6.914684e-02 2.656858e-01 11 86007542 86007583 42 - 1.730 1.648 -0.280
ENSG00000073921 E043 63.9286192 2.579831e-04 8.377032e-04 1.307690e-02 11 86011030 86011111 82 - 1.873 1.746 -0.430
ENSG00000073921 E044 36.4921682 4.813150e-03 2.390849e-01 5.280211e-01 11 86011112 86011136 25 - 1.608 1.539 -0.234
ENSG00000073921 E045 52.0914221 8.797973e-03 1.320250e-01 3.855454e-01 11 86012281 86012328 48 - 1.768 1.680 -0.298
ENSG00000073921 E046 40.4486513 7.232709e-03 4.032241e-01 6.862354e-01 11 86012329 86012342 14 - 1.643 1.591 -0.176
ENSG00000073921 E047 57.2844365 2.841627e-04 1.292273e-01 3.813816e-01 11 86012343 86012392 50 - 1.796 1.734 -0.208
ENSG00000073921 E048 78.5902887 1.851558e-03 6.133472e-02 2.487091e-01 11 86014870 86014963 94 - 1.937 1.864 -0.244
ENSG00000073921 E049 39.8128447 2.021861e-03 1.375103e-02 9.884689e-02 11 86022367 86022377 11 - 1.671 1.545 -0.428
ENSG00000073921 E050 66.2503354 6.478389e-04 3.457965e-02 1.776867e-01 11 86022378 86022469 92 - 1.868 1.786 -0.275
ENSG00000073921 E051 0.8596780 1.621725e-02 7.006983e-01 8.781003e-01 11 86023416 86023541 126 - 0.239 0.297 0.423
ENSG00000073921 E052 42.5432305 1.653506e-02 1.669744e-01 4.374096e-01 11 86026292 86026367 76 - 1.687 1.589 -0.333
ENSG00000073921 E053 51.8234122 4.625191e-03 4.716178e-01 7.389748e-01 11 86031469 86031611 143 - 1.742 1.704 -0.129
ENSG00000073921 E054 30.8131922 4.823780e-04 5.757997e-01 8.101845e-01 11 86068651 86068733 83 - 1.518 1.487 -0.107
ENSG00000073921 E055 14.2862124 9.806825e-04 4.358176e-01 7.122678e-01 11 86068734 86068738 5 - 1.214 1.154 -0.215
ENSG00000073921 E056 21.1971168 6.348436e-04 7.998707e-02 2.902916e-01 11 86068739 86069022 284 - 1.401 1.288 -0.393
ENSG00000073921 E057 2.5287782 5.953679e-03 5.135034e-02 2.245079e-01 11 86069023 86069097 75 - 0.669 0.393 -1.314
ENSG00000073921 E058 0.0000000       11 86069246 86069457 212 -      
ENSG00000073921 E059 0.0000000       11 86069458 86069719 262 -      
ENSG00000073921 E060 0.2454921 1.661811e-02 9.950148e-01   11 86069720 86069882 163 - 0.095 0.095 0.007

Help

Please Click HERE to learn more details about the results from DEXseq.