ENSG00000075240

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361034 ENSG00000075240 No_inf pgKDN_inf GRAMD4 protein_coding protein_coding 39.81182 24.22849 44.91872 4.985352 6.08563 0.8903378 3.8518332 1.4138683 4.373699 1.4138683 4.3736993 1.622333 0.09323333 0.080900 0.069350 -0.011550 0.997286909 0.002446743 FALSE TRUE
ENST00000406902 ENSG00000075240 No_inf pgKDN_inf GRAMD4 protein_coding protein_coding 39.81182 24.22849 44.91872 4.985352 6.08563 0.8903378 2.9166285 0.0000000 3.364910 0.0000000 1.2641254 8.398705 0.06275000 0.000000 0.075050 0.075050 0.066987578 0.002446743 FALSE TRUE
ENST00000431155 ENSG00000075240 No_inf pgKDN_inf GRAMD4 protein_coding protein_coding 39.81182 24.22849 44.91872 4.985352 6.08563 0.8903378 1.7571169 2.4027552 0.000000 2.4027552 0.0000000 -7.914538 0.03958333 0.061650 0.000000 -0.061650 0.788705361 0.002446743 FALSE FALSE
ENST00000447351 ENSG00000075240 No_inf pgKDN_inf GRAMD4 protein_coding protein_coding 39.81182 24.22849 44.91872 4.985352 6.08563 0.8903378 0.8174455 2.4523364 0.000000 2.4523364 0.0000000 -7.943884 0.02097500 0.062925 0.000000 -0.062925 0.788916161 0.002446743 FALSE FALSE
ENST00000490378 ENSG00000075240 No_inf pgKDN_inf GRAMD4 protein_coding protein_coding_CDS_not_defined 39.81182 24.22849 44.91872 4.985352 6.08563 0.8903378 4.5565233 0.0000000 7.015539 0.0000000 7.0155391 9.456465 0.06925833 0.000000 0.111250 0.111250 0.899690107 0.002446743   FALSE
MSTRG.19580.12 ENSG00000075240 No_inf pgKDN_inf GRAMD4 protein_coding   39.81182 24.22849 44.91872 4.985352 6.08563 0.8903378 1.8469092 2.6165521 1.200347 0.7257856 0.5451471 -1.117749 0.05970833 0.115175 0.026350 -0.088825 0.247001808 0.002446743 FALSE FALSE
MSTRG.19580.2 ENSG00000075240 No_inf pgKDN_inf GRAMD4 protein_coding   39.81182 24.22849 44.91872 4.985352 6.08563 0.8903378 12.2262675 6.4979821 15.812589 1.0584756 1.9628508 1.281703 0.32779167 0.314575 0.380675 0.066100 0.851289365 0.002446743 FALSE TRUE
MSTRG.19580.5 ENSG00000075240 No_inf pgKDN_inf GRAMD4 protein_coding   39.81182 24.22849 44.91872 4.985352 6.08563 0.8903378 5.7395366 0.6236639 11.569131 0.6236639 4.1380330 4.191665 0.14252500 0.035675 0.297000 0.261325 0.203244935 0.002446743 FALSE TRUE
MSTRG.19580.9 ENSG00000075240 No_inf pgKDN_inf GRAMD4 protein_coding   39.81182 24.22849 44.91872 4.985352 6.08563 0.8903378 2.8851902 6.1702108 0.000000 2.5255136 0.0000000 -9.271512 0.09761667 0.231650 0.000000 -0.231650 0.002446743 0.002446743 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000075240 E001 0.0000000       22 46576012 46576078 67 +      
ENSG00000075240 E002 0.6018839 0.1675134215 0.589776886 0.81834862 22 46577083 46577128 46 + 0.230 0.128 -1.020
ENSG00000075240 E003 2.1817052 0.0103447832 0.979304199 0.99748771 22 46577129 46577215 87 + 0.490 0.486 -0.019
ENSG00000075240 E004 5.5437177 0.0028112068 0.435981585 0.71248768 22 46577216 46577290 75 + 0.829 0.738 -0.363
ENSG00000075240 E005 1.4220974 0.0090115388 0.040179364 0.19428311 22 46620309 46620360 52 + 0.465 0.128 -2.478
ENSG00000075240 E006 0.9438867 0.0118908157 0.025108128 0.14573005 22 46620386 46620565 180 + 0.379 0.000 -12.139
ENSG00000075240 E007 6.1506947 0.0103283990 0.536732643 0.78597210 22 46626751 46626760 10 + 0.862 0.789 -0.282
ENSG00000075240 E008 13.6305829 0.0023149953 0.424483126 0.70369684 22 46626761 46626842 82 + 1.169 1.104 -0.235
ENSG00000075240 E009 14.6966466 0.0010783146 0.170725090 0.44302767 22 46626843 46626916 74 + 1.213 1.104 -0.391
ENSG00000075240 E010 10.1165047 0.0013684747 0.217746991 0.50424930 22 46626917 46626961 45 + 1.065 0.950 -0.426
ENSG00000075240 E011 14.9731665 0.0042959322 0.494622487 0.75596051 22 46637840 46637960 121 + 1.204 1.148 -0.197
ENSG00000075240 E012 1.1259488 0.4743518211 0.099604828 0.32977819 22 46650478 46650642 165 + 0.130 0.532 2.787
ENSG00000075240 E013 21.0259178 0.0007555811 0.461583324 0.73223335 22 46658187 46658307 121 + 1.341 1.292 -0.171
ENSG00000075240 E014 13.2287050 0.0010798848 0.389189402 0.67504868 22 46661381 46661442 62 + 1.109 1.179 0.251
ENSG00000075240 E015 14.6744281 0.0039093005 0.550564573 0.79484576 22 46663040 46663106 67 + 1.159 1.208 0.174
ENSG00000075240 E016 20.5541913 0.0006454227 0.716682885 0.88577787 22 46663107 46663172 66 + 1.323 1.299 -0.083
ENSG00000075240 E017 19.9387207 0.0009626927 0.675747126 0.86575636 22 46663838 46663863 26 + 1.312 1.284 -0.098
ENSG00000075240 E018 28.8408041 0.0025370475 0.264659479 0.55778451 22 46664026 46664117 92 + 1.478 1.411 -0.233
ENSG00000075240 E019 22.0741219 0.0006782788 0.228708464 0.51745794 22 46665615 46665706 92 + 1.371 1.292 -0.275
ENSG00000075240 E020 15.4416707 0.0010060642 0.337643023 0.62944746 22 46666825 46666873 49 + 1.222 1.148 -0.263
ENSG00000075240 E021 15.4152955 0.0009340119 0.083897910 0.29883436 22 46668096 46668167 72 + 1.240 1.104 -0.486
ENSG00000075240 E022 0.1265070 0.0123177220 0.259369522   22 46668168 46668247 80 + 0.000 0.128 9.654
ENSG00000075240 E023 13.7293564 0.0012582732 0.092345088 0.31561594 22 46668689 46668732 44 + 1.194 1.054 -0.504
ENSG00000075240 E024 20.5051997 0.0006879180 0.176145014 0.45029429 22 46668799 46668908 110 + 1.344 1.252 -0.323
ENSG00000075240 E025 1.3818246 0.3065638331 0.024910195 0.14512455 22 46671050 46671167 118 + 0.130 0.612 3.151
ENSG00000075240 E026 29.3305467 0.0004576479 0.450637327 0.72384887 22 46672843 46672997 155 + 1.447 1.490 0.148
ENSG00000075240 E027 29.3971305 0.0007280709 0.912489612 0.97218716 22 46673670 46673814 145 + 1.466 1.460 -0.019
ENSG00000075240 E028 0.0000000       22 46674608 46674656 49 +      
ENSG00000075240 E029 31.2548839 0.0004494296 0.172575336 0.44536476 22 46674657 46674750 94 + 1.515 1.439 -0.260
ENSG00000075240 E030 26.5359316 0.0153730354 0.255433074 0.54742619 22 46675468 46675552 85 + 1.450 1.362 -0.305
ENSG00000075240 E031 2.6030563 0.0053694834 0.002312581 0.02844396 22 46676393 46676599 207 + 0.346 0.764 1.981
ENSG00000075240 E032 21.6220464 0.0216333570 0.270783834 0.56447933 22 46676600 46676668 69 + 1.301 1.393 0.321
ENSG00000075240 E033 65.6397100 0.0002861158 0.079408958 0.28906876 22 46677147 46677575 429 + 1.780 1.846 0.223
ENSG00000075240 E034 301.1907977 0.0001162585 0.007554231 0.06651539 22 46677576 46679790 2215 + 2.446 2.486 0.132

Help

Please Click HERE to learn more details about the results from DEXseq.