ENSG00000075391

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000462775 ENSG00000075391 No_inf pgKDN_inf RASAL2 protein_coding protein_coding 32.49166 40.74502 31.86215 1.681355 1.848622 -0.3546813 4.635103 7.742229 4.6007789 1.106614 0.8224541 -0.7496007 0.13395000 0.191425 0.144075 -0.047350 8.288466e-01 1.587535e-05 FALSE TRUE
ENST00000463079 ENSG00000075391 No_inf pgKDN_inf RASAL2 protein_coding retained_intron 32.49166 40.74502 31.86215 1.681355 1.848622 -0.3546813 10.830281 10.276479 11.9458029 1.113054 1.7582498 0.2169618 0.34462500 0.252600 0.370075 0.117475 4.657172e-01 1.587535e-05 FALSE FALSE
MSTRG.2301.1 ENSG00000075391 No_inf pgKDN_inf RASAL2 protein_coding   32.49166 40.74502 31.86215 1.681355 1.848622 -0.3546813 7.793814 5.214150 10.3085279 1.073123 1.0023009 0.9819688 0.25690833 0.126450 0.329350 0.202900 6.218484e-02 1.587535e-05 FALSE TRUE
MSTRG.2301.14 ENSG00000075391 No_inf pgKDN_inf RASAL2 protein_coding   32.49166 40.74502 31.86215 1.681355 1.848622 -0.3546813 1.379836 4.139508 0.0000000 1.106707 0.0000000 -8.6967964 0.03383333 0.101500 0.000000 -0.101500 1.587535e-05 1.587535e-05 FALSE TRUE
MSTRG.2301.2 ENSG00000075391 No_inf pgKDN_inf RASAL2 protein_coding   32.49166 40.74502 31.86215 1.681355 1.848622 -0.3546813 2.012714 2.832103 2.1125791 1.163451 0.3742325 -0.4211408 0.06010833 0.069850 0.068250 -0.001600 9.489620e-01 1.587535e-05   FALSE
MSTRG.2301.4 ENSG00000075391 No_inf pgKDN_inf RASAL2 protein_coding   32.49166 40.74502 31.86215 1.681355 1.848622 -0.3546813 1.731781 3.403400 0.5690745 1.388722 0.4080241 -2.5593888 0.05050000 0.084700 0.015950 -0.068750 5.551276e-01 1.587535e-05 TRUE FALSE
MSTRG.2301.7 ENSG00000075391 No_inf pgKDN_inf RASAL2 protein_coding   32.49166 40.74502 31.86215 1.681355 1.848622 -0.3546813 1.075034 3.225101 0.0000000 2.039633 0.0000000 -8.3376670 0.02490000 0.074700 0.000000 -0.074700 5.257201e-01 1.587535e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000075391 E001 1.2263887 0.0209093683 6.969295e-01 8.762562e-01 1 178094013 178094049 37 + 0.377 0.319 -0.347
ENSG00000075391 E002 2.6874116 0.0586768638 3.863507e-01 6.722405e-01 1 178094050 178094103 54 + 0.635 0.501 -0.610
ENSG00000075391 E003 7.1074319 0.0071765271 4.710930e-05 1.270397e-03 1 178094104 178094224 121 + 1.100 0.671 -1.652
ENSG00000075391 E004 23.9557227 0.0005640307 9.349997e-03 7.696375e-02 1 178094225 178094694 470 + 1.473 1.322 -0.524
ENSG00000075391 E005 0.2541163 0.0160420560 3.411974e-01   1 178120961 178121087 127 + 0.000 0.157 11.212
ENSG00000075391 E006 1.8469131 0.1699708040 7.071981e-01 8.811693e-01 1 178123056 178123182 127 + 0.424 0.470 0.240
ENSG00000075391 E007 0.6003758 0.1551613071 1.445890e-01 4.048071e-01 1 178123719 178123815 97 + 0.323 0.085 -2.347
ENSG00000075391 E008 1.0141379 0.4832032957 8.101671e-02 2.924540e-01 1 178125182 178125326 145 + 0.000 0.437 12.259
ENSG00000075391 E009 2.7201562 0.0052411050 4.864777e-01 7.501242e-01 1 178125327 178125501 175 + 0.506 0.606 0.461
ENSG00000075391 E010 0.8610324 0.0121886605 9.627769e-01 9.919625e-01 1 178132790 178132837 48 + 0.262 0.271 0.068
ENSG00000075391 E011 71.7314543 0.0008845259 1.323735e-15 2.371905e-13 1 178134565 178137465 2901 + 1.644 1.965 1.082
ENSG00000075391 E012 1.8557468 0.1045466120 5.309441e-01 7.817192e-01 1 178230310 178233880 3571 + 0.376 0.501 0.653
ENSG00000075391 E013 11.6852598 0.0376830866 9.927355e-01 1.000000e+00 1 178283564 178283691 128 + 1.100 1.097 -0.011
ENSG00000075391 E014 11.1914918 0.0015913991 8.060847e-01 9.281677e-01 1 178299992 178300118 127 + 1.091 1.074 -0.060
ENSG00000075391 E015 0.1272623 0.0123516102 6.909075e-01   1 178341471 178341608 138 + 0.000 0.085 10.266
ENSG00000075391 E016 0.0000000       1 178371374 178371475 102 +      
ENSG00000075391 E017 0.0000000       1 178372203 178372322 120 +      
ENSG00000075391 E018 0.4887212 0.0794346156 8.051269e-01   1 178389010 178389307 298 + 0.191 0.157 -0.347
ENSG00000075391 E019 12.8448562 0.0012105377 7.975980e-02 2.898764e-01 1 178390100 178390206 107 + 1.209 1.074 -0.484
ENSG00000075391 E020 13.2783782 0.0010632156 6.520798e-03 5.994421e-02 1 178420511 178420620 110 + 1.258 1.049 -0.746
ENSG00000075391 E021 20.1123068 0.0006672803 1.256904e-03 1.784884e-02 1 178439422 178439575 154 + 1.426 1.221 -0.716
ENSG00000075391 E022 14.6078698 0.0009971825 1.510464e-03 2.061868e-02 1 178441549 178441647 99 + 1.308 1.074 -0.832
ENSG00000075391 E023 65.1535358 0.0002572640 4.487924e-05 1.220019e-03 1 178442675 178443229 555 + 1.894 1.748 -0.493
ENSG00000075391 E024 23.2254473 0.0010076240 1.558799e-02 1.078956e-01 1 178445518 178445662 145 + 1.456 1.312 -0.499
ENSG00000075391 E025 26.4998475 0.0006216237 8.091949e-07 3.848600e-05 1 178451571 178451715 145 + 1.573 1.294 -0.965
ENSG00000075391 E026 10.2596152 0.0013087338 7.405936e-02 2.772484e-01 1 178452416 178452436 21 + 1.128 0.976 -0.553
ENSG00000075391 E027 29.5060114 0.0005025277 3.339443e-02 1.737838e-01 1 178452437 178452652 216 + 1.540 1.429 -0.383
ENSG00000075391 E028 32.0576807 0.0010858543 1.365794e-02 9.842696e-02 1 178454447 178454648 202 + 1.583 1.456 -0.435
ENSG00000075391 E029 6.8113601 0.0019653161 1.688918e-01 4.403253e-01 1 178456475 178456699 225 + 0.795 0.945 0.575
ENSG00000075391 E030 11.8480538 0.0011624196 5.386016e-02 2.309120e-01 1 178456700 178456720 21 + 1.186 1.032 -0.555
ENSG00000075391 E031 43.3900961 0.0005837003 1.763618e-03 2.317150e-02 1 178456721 178456899 179 + 1.717 1.579 -0.469
ENSG00000075391 E032 131.8988133 0.0001926861 5.578416e-05 1.459099e-03 1 178457683 178458544 862 + 2.173 2.073 -0.333
ENSG00000075391 E033 0.3709943 0.0166315922 7.510211e-01   1 178459045 178459078 34 + 0.106 0.157 0.653
ENSG00000075391 E034 25.6386195 0.0009324850 1.640585e-03 2.192351e-02 1 178464278 178464412 135 + 1.515 1.335 -0.622
ENSG00000075391 E035 52.7616687 0.0002744361 3.214223e-03 3.635821e-02 1 178465920 178466122 203 + 1.789 1.672 -0.394
ENSG00000075391 E036 31.1741102 0.0004930203 3.235206e-01 6.161984e-01 1 178467334 178467421 88 + 1.530 1.481 -0.165
ENSG00000075391 E037 0.4907023 0.0158125541 8.033820e-01   1 178470693 178470723 31 + 0.191 0.157 -0.347
ENSG00000075391 E038 1070.2418541 0.0001273165 2.530638e-23 9.099161e-21 1 178473075 178484147 11073 + 2.984 3.052 0.224

Help

Please Click HERE to learn more details about the results from DEXseq.