ENSG00000075413

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000216288 ENSG00000075413 No_inf pgKDN_inf MARK3 protein_coding protein_coding 41.66965 40.40066 41.18256 1.659134 1.972095 0.02764771 6.5192908 1.535141 11.4213030 1.5351415 2.4243430 2.887179 0.15953333 0.041900 0.279100 0.237200 0.01547518 0.01547518 FALSE TRUE
ENST00000303622 ENSG00000075413 No_inf pgKDN_inf MARK3 protein_coding protein_coding 41.66965 40.40066 41.18256 1.659134 1.972095 0.02764771 0.8758625 0.000000 2.6275876 0.0000000 2.6275876 8.043075 0.01926667 0.000000 0.057800 0.057800 0.84241900 0.01547518 FALSE TRUE
ENST00000554627 ENSG00000075413 No_inf pgKDN_inf MARK3 protein_coding protein_coding 41.66965 40.40066 41.18256 1.659134 1.972095 0.02764771 2.4892624 2.748589 2.4672487 0.9819863 1.4424053 -0.155192 0.05906667 0.065650 0.060675 -0.004975 0.84876979 0.01547518 FALSE TRUE
ENST00000558611 ENSG00000075413 No_inf pgKDN_inf MARK3 protein_coding retained_intron 41.66965 40.40066 41.18256 1.659134 1.972095 0.02764771 2.3560756 3.003320 1.3482793 0.6638011 0.5265942 -1.149574 0.05597500 0.074200 0.031550 -0.042650 0.57398020 0.01547518 FALSE TRUE
ENST00000559274 ENSG00000075413 No_inf pgKDN_inf MARK3 protein_coding retained_intron 41.66965 40.40066 41.18256 1.659134 1.972095 0.02764771 7.3409248 9.610769 6.6689629 0.7305297 1.0214316 -0.526528 0.17627500 0.237425 0.159550 -0.077875 0.53143214 0.01547518 FALSE FALSE
ENST00000676938 ENSG00000075413 No_inf pgKDN_inf MARK3 protein_coding protein_coding 41.66965 40.40066 41.18256 1.659134 1.972095 0.02764771 1.8887981 0.000000 4.3413922 0.0000000 2.5210367 8.765333 0.04880000 0.000000 0.112675 0.112675 0.48993158 0.01547518 FALSE TRUE
MSTRG.9106.64 ENSG00000075413 No_inf pgKDN_inf MARK3 protein_coding   41.66965 40.40066 41.18256 1.659134 1.972095 0.02764771 3.4228117 5.874703 0.9703727 2.1281999 0.9703727 -2.585567 0.08125833 0.143175 0.023050 -0.120125 0.26715260 0.01547518 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000075413 E001 0.1187032 0.0118460318 5.870538e-01   14 103385377 103385379 3 + 0.092 0.000 -11.384
ENSG00000075413 E002 0.1187032 0.0118460318 5.870538e-01   14 103385380 103385380 1 + 0.092 0.000 -13.915
ENSG00000075413 E003 0.1187032 0.0118460318 5.870538e-01   14 103385381 103385388 8 + 0.092 0.000 -13.915
ENSG00000075413 E004 0.3549719 0.0157835159 1.209541e-01   14 103385389 103385389 1 + 0.232 0.000 -15.374
ENSG00000075413 E005 0.3549719 0.0157835159 1.209541e-01   14 103385390 103385391 2 + 0.232 0.000 -15.374
ENSG00000075413 E006 0.5906791 0.0144133468 2.601648e-02 1.491471e-01 14 103385392 103385396 5 + 0.338 0.000 -16.028
ENSG00000075413 E007 0.5906791 0.0144133468 2.601648e-02 1.491471e-01 14 103385397 103385410 14 + 0.338 0.000 -16.028
ENSG00000075413 E008 0.8263862 0.0126937001 6.168480e-03 5.760174e-02 14 103385411 103385412 2 + 0.423 0.000 -16.444
ENSG00000075413 E009 0.8263862 0.0126937001 6.168480e-03 5.760174e-02 14 103385413 103385414 2 + 0.423 0.000 -16.444
ENSG00000075413 E010 0.9536485 0.0118531334 3.538781e-02 1.800563e-01 14 103385415 103385422 8 + 0.423 0.098 -2.697
ENSG00000075413 E011 0.9536485 0.0118531334 3.538781e-02 1.800563e-01 14 103385423 103385424 2 + 0.423 0.098 -2.697
ENSG00000075413 E012 3.1223649 0.0525816768 2.463538e-02 1.442341e-01 14 103385425 103385452 28 + 0.757 0.402 -1.627
ENSG00000075413 E013 7.5131569 0.0346758896 1.143287e-01 3.562016e-01 14 103385453 103385540 88 + 1.018 0.819 -0.753
ENSG00000075413 E014 9.5845430 0.0249417736 9.550190e-02 3.217641e-01 14 103385541 103385697 157 + 1.107 0.923 -0.676
ENSG00000075413 E015 10.7329659 0.0477140954 7.222375e-01 8.883174e-01 14 103385698 103385859 162 + 1.098 1.038 -0.219
ENSG00000075413 E016 7.7571535 0.0018065272 5.687736e-02 2.382065e-01 14 103385860 103385979 120 + 1.028 0.836 -0.724
ENSG00000075413 E017 4.5014315 0.0031621198 3.776576e-01 6.647277e-01 14 103385980 103385984 5 + 0.791 0.683 -0.443
ENSG00000075413 E018 10.3116082 0.0115170377 5.470582e-02 2.329497e-01 14 103385985 103386029 45 + 1.137 0.949 -0.691
ENSG00000075413 E019 9.3187102 0.0328728358 3.226010e-02 1.699477e-01 14 103386030 103386040 11 + 1.122 0.867 -0.947
ENSG00000075413 E020 12.0012760 0.0351019733 6.351117e-02 2.535651e-01 14 103386041 103386080 40 + 1.206 0.996 -0.761
ENSG00000075413 E021 0.0000000       14 103386239 103386388 150 +      
ENSG00000075413 E022 0.0000000       14 103393762 103393804 43 +      
ENSG00000075413 E023 0.7257114 0.1214058920 5.302024e-01 7.813645e-01 14 103398951 103399041 91 + 0.288 0.179 -0.890
ENSG00000075413 E024 11.0077428 0.0017487692 4.533651e-03 4.626640e-02 14 103405076 103405133 58 + 1.187 0.936 -0.914
ENSG00000075413 E025 17.0663075 0.0058315790 1.301767e-03 1.835542e-02 14 103405134 103405267 134 + 1.365 1.112 -0.890
ENSG00000075413 E026 0.2543986 0.0159290148 2.141860e-01   14 103411645 103411688 44 + 0.000 0.179 14.128
ENSG00000075413 E027 0.5072867 0.0461723344 3.977683e-02 1.933072e-01 14 103411689 103411749 61 + 0.000 0.305 14.958
ENSG00000075413 E028 0.0000000       14 103411750 103411765 16 +      
ENSG00000075413 E029 0.3700180 0.2657731753 5.922531e-01   14 103416790 103416839 50 + 0.092 0.178 1.110
ENSG00000075413 E030 0.0000000       14 103417273 103417323 51 +      
ENSG00000075413 E031 0.1272623 0.0123504815 4.931711e-01   14 103417328 103417461 134 + 0.000 0.098 13.191
ENSG00000075413 E032 0.2459004 0.0165206820 9.466087e-01   14 103427748 103427835 88 + 0.092 0.098 0.110
ENSG00000075413 E033 12.4043526 0.0143177087 1.844264e-01 4.615722e-01 14 103428387 103428440 54 + 1.187 1.058 -0.463
ENSG00000075413 E034 0.0000000       14 103429193 103429373 181 +      
ENSG00000075413 E035 0.0000000       14 103438021 103438024 4 +      
ENSG00000075413 E036 0.0000000       14 103438025 103438184 160 +      
ENSG00000075413 E037 0.1272623 0.0123504815 4.931711e-01   14 103438185 103438333 149 + 0.000 0.098 13.191
ENSG00000075413 E038 0.1186381 0.0118847496 5.869510e-01   14 103441470 103441563 94 + 0.092 0.000 -13.915
ENSG00000075413 E039 10.3389724 0.0013714144 1.499837e-01 4.124821e-01 14 103448919 103448967 49 + 1.115 0.984 -0.475
ENSG00000075413 E040 15.9315357 0.0092188380 1.334801e-01 3.881621e-01 14 103451918 103451983 66 + 1.287 1.161 -0.447
ENSG00000075413 E041 0.0000000       14 103451984 103451995 12 +      
ENSG00000075413 E042 0.1268540 0.0124254768 4.930084e-01   14 103457027 103457141 115 + 0.000 0.098 13.191
ENSG00000075413 E043 20.3122816 0.0007660517 9.195738e-02 3.148771e-01 14 103457142 103457212 71 + 1.382 1.268 -0.396
ENSG00000075413 E044 0.3561095 0.5410057173 3.232099e-01   14 103457213 103458195 983 + 0.233 0.000 -14.598
ENSG00000075413 E045 0.3612703 0.2125020896 6.850176e-01   14 103458727 103458795 69 + 0.168 0.098 -0.889
ENSG00000075413 E046 15.1414448 0.0009168164 6.786926e-01 8.670805e-01 14 103462405 103462461 57 + 1.225 1.190 -0.123
ENSG00000075413 E047 26.0108760 0.0005953986 6.937324e-01 8.748950e-01 14 103465557 103465713 157 + 1.445 1.418 -0.094
ENSG00000075413 E048 15.8176533 0.0008722849 1.517058e-01 4.152009e-01 14 103465714 103465793 80 + 1.277 1.168 -0.383
ENSG00000075413 E049 0.8631435 0.0161343751 6.257060e-01 8.389746e-01 14 103465794 103465971 178 + 0.232 0.305 0.525
ENSG00000075413 E050 16.4761200 0.0008089317 5.400255e-01 7.882182e-01 14 103465972 103466052 81 + 1.266 1.218 -0.169
ENSG00000075413 E051 14.8274551 0.0022512735 5.790897e-01 8.119182e-01 14 103466053 103466091 39 + 1.180 1.218 0.134
ENSG00000075413 E052 0.6356513 0.0146834489 1.599250e-02 1.096480e-01 14 103466092 103466342 251 + 0.000 0.356 15.339
ENSG00000075413 E053 24.8408881 0.0013776445 8.106536e-02 2.925317e-01 14 103466343 103466442 100 + 1.463 1.354 -0.376
ENSG00000075413 E054 0.4900381 0.0159093752 9.311251e-01   14 103466443 103466831 389 + 0.168 0.179 0.110
ENSG00000075413 E055 28.2620982 0.0082873238 2.301492e-01 5.186940e-01 14 103467079 103467191 113 + 1.507 1.422 -0.291
ENSG00000075413 E056 7.4697728 0.0299983950 8.186237e-04 1.284972e-02 14 103467192 103467656 465 + 0.678 1.086 1.570
ENSG00000075413 E057 2.5559042 0.0090445298 6.551788e-01 8.553712e-01 14 103467714 103467754 41 + 0.583 0.517 -0.305
ENSG00000075413 E058 8.6427464 0.0113957156 3.651237e-02 1.838023e-01 14 103467755 103468032 278 + 0.867 1.077 0.782
ENSG00000075413 E059 11.5624112 0.0027811934 1.051002e-01 3.390438e-01 14 103468033 103468080 48 + 1.028 1.161 0.480
ENSG00000075413 E060 13.0302257 0.0073407352 1.911890e-01 4.706124e-01 14 103468081 103468085 5 + 1.090 1.197 0.383
ENSG00000075413 E061 32.0021221 0.0005562466 2.061220e-01 4.897392e-01 14 103468086 103468186 101 + 1.487 1.548 0.209
ENSG00000075413 E062 0.0000000       14 103469203 103469303 101 +      
ENSG00000075413 E063 50.0706448 0.0003295377 3.529919e-02 1.798268e-01 14 103474993 103475210 218 + 1.665 1.748 0.280
ENSG00000075413 E064 0.5872807 0.0375274920 2.809161e-02 1.566635e-01 14 103475211 103475714 504 + 0.338 0.000 -15.951
ENSG00000075413 E065 0.0000000       14 103478775 103478839 65 +      
ENSG00000075413 E066 25.8831482 0.0033408533 5.672179e-01 8.050613e-01 14 103480387 103480436 50 + 1.449 1.409 -0.136
ENSG00000075413 E067 28.3234392 0.0021588594 1.371644e-02 9.867711e-02 14 103480437 103480490 54 + 1.534 1.387 -0.506
ENSG00000075413 E068 6.8002302 0.0117914665 2.786796e-02 1.558837e-01 14 103480491 103481655 1165 + 0.757 0.996 0.917
ENSG00000075413 E069 0.0000000       14 103481801 103481815 15 +      
ENSG00000075413 E070 0.0000000       14 103481816 103481829 14 +      
ENSG00000075413 E071 0.0000000       14 103481830 103481861 32 +      
ENSG00000075413 E072 0.0000000       14 103481862 103481929 68 +      
ENSG00000075413 E073 0.2362687 0.0157279979 2.737902e-01   14 103481930 103482067 138 + 0.168 0.000 -14.840
ENSG00000075413 E074 3.3492846 0.0099501169 5.565692e-02 2.350482e-01 14 103485308 103486113 806 + 0.494 0.746 1.110
ENSG00000075413 E075 2.1135799 0.0367761777 7.929789e-02 2.887535e-01 14 103486118 103486605 488 + 0.338 0.608 1.373
ENSG00000075413 E076 1.6224978 0.0088443287 3.383910e-02 1.750674e-01 14 103486606 103487118 513 + 0.232 0.549 1.847
ENSG00000075413 E077 0.1272623 0.0123504815 4.931711e-01   14 103487119 103487180 62 + 0.000 0.098 13.191
ENSG00000075413 E078 0.2442663 0.0163767887 9.463682e-01   14 103487181 103487290 110 + 0.092 0.098 0.110
ENSG00000075413 E079 0.3621491 0.0165720484 6.392506e-01   14 103487291 103487378 88 + 0.168 0.098 -0.890
ENSG00000075413 E080 2.9839932 0.0050471287 2.417559e-02 1.424545e-01 14 103487379 103487707 329 + 0.423 0.726 1.390
ENSG00000075413 E081 5.4816338 0.0696281381 7.309728e-01 8.931581e-01 14 103487708 103489052 1345 + 0.838 0.784 -0.212
ENSG00000075413 E082 2.9273132 0.0059338703 8.462122e-01 9.453871e-01 14 103489053 103489396 344 + 0.609 0.579 -0.131
ENSG00000075413 E083 14.4163761 0.0140196892 6.285544e-02 2.520571e-01 14 103489397 103490951 1555 + 1.098 1.262 0.583
ENSG00000075413 E084 0.9810873 0.0124980664 9.025093e-01 9.688647e-01 14 103490952 103490977 26 + 0.288 0.305 0.110
ENSG00000075413 E085 0.7355302 0.0149167689 9.156615e-01 9.735655e-01 14 103490978 103490981 4 + 0.232 0.246 0.110
ENSG00000075413 E086 2.3429898 0.0092104164 3.914466e-01 6.765673e-01 14 103490982 103491107 126 + 0.460 0.579 0.569
ENSG00000075413 E087 4.9155538 0.0148788348 3.971288e-01 6.814558e-01 14 103491108 103491538 431 + 0.719 0.819 0.400
ENSG00000075413 E088 3.2850486 0.0068582742 4.666744e-01 7.353291e-01 14 103491539 103491776 238 + 0.679 0.579 -0.431
ENSG00000075413 E089 67.7555863 0.0002850619 9.267414e-01 9.781001e-01 14 103491777 103492034 258 + 1.838 1.837 -0.005
ENSG00000075413 E090 19.2934366 0.0008221215 7.426801e-10 6.523731e-08 14 103494732 103498501 3770 + 1.047 1.469 1.491
ENSG00000075413 E091 3.6741083 0.0211349242 8.408104e-01 9.429091e-01 14 103498502 103498528 27 + 0.656 0.683 0.110
ENSG00000075413 E092 3.1152465 0.0307431708 2.539978e-02 1.467815e-01 14 103498529 103498826 298 + 0.423 0.746 1.472
ENSG00000075413 E093 0.5085150 0.0156920059 3.674757e-02 1.845557e-01 14 103498827 103498864 38 + 0.000 0.305 15.048
ENSG00000075413 E094 1.2615494 0.0179900746 5.389400e-03 5.231461e-02 14 103498865 103498901 37 + 0.092 0.517 3.280
ENSG00000075413 E095 10.5665220 0.0260454533 2.449193e-04 4.943666e-03 14 103498902 103500155 1254 + 0.823 1.218 1.456
ENSG00000075413 E096 5.7863294 0.0028884121 1.923436e-01 4.722700e-01 14 103500156 103500200 45 + 0.757 0.896 0.543
ENSG00000075413 E097 125.9740871 0.0001539808 3.033103e-02 1.638676e-01 14 103502882 103503831 950 + 2.078 2.128 0.166

Help

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