ENSG00000075426

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264716 ENSG00000075426 No_inf pgKDN_inf FOSL2 protein_coding protein_coding 23.83276 17.34517 28.00056 0.2270855 3.662251 0.6906049 14.863845 6.676752 16.456462 0.6006934 0.7699955 1.3001532 0.60725000 0.385350 0.61475 0.229400 0.26392241 0.02302099 FALSE TRUE
ENST00000460736 ENSG00000075426 No_inf pgKDN_inf FOSL2 protein_coding protein_coding_CDS_not_defined 23.83276 17.34517 28.00056 0.2270855 3.662251 0.6906049 1.094104 0.000000 3.282313 0.0000000 3.2823125 8.3629575 0.02806667 0.000000 0.08420 0.084200 0.87090169 0.02302099 FALSE FALSE
MSTRG.15999.6 ENSG00000075426 No_inf pgKDN_inf FOSL2 protein_coding   23.83276 17.34517 28.00056 0.2270855 3.662251 0.6906049 6.243274 9.016687 7.072255 0.7599857 1.0689746 -0.3499878 0.29025833 0.518775 0.25215 -0.266625 0.02302099 0.02302099 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000075426 E001 0.0000000       2 28392448 28392544 97 +      
ENSG00000075426 E002 0.0000000       2 28392802 28392836 35 +      
ENSG00000075426 E003 0.2459004 0.0162457893 8.145945e-01   2 28392858 28392884 27 + 0.083 0.109 0.435
ENSG00000075426 E004 49.2166849 0.0013174631 6.549894e-05 1.660066e-03 2 28392885 28393822 938 + 1.769 1.589 -0.608
ENSG00000075426 E005 0.1187032 0.0117917589 7.271958e-01   2 28395511 28395776 266 + 0.083 0.000 -8.795
ENSG00000075426 E006 26.5408171 0.0005320085 1.194048e-04 2.749778e-03 2 28404107 28404358 252 + 1.524 1.296 -0.788
ENSG00000075426 E007 15.5557478 0.0024287512 2.850562e-03 3.323438e-02 2 28408759 28408866 108 + 1.304 1.072 -0.825
ENSG00000075426 E008 1.0805938 0.0110835444 2.056558e-01 4.890150e-01 2 28410191 28410225 35 + 0.393 0.196 -1.373
ENSG00000075426 E009 1.1060489 0.0128005115 4.384506e-01 7.146387e-01 2 28410473 28410575 103 + 0.265 0.384 0.757
ENSG00000075426 E010 0.6262717 0.0148765220 9.086447e-02 3.130628e-01 2 28411879 28411929 51 + 0.083 0.330 2.435
ENSG00000075426 E011 580.3400890 0.0000674845 5.512873e-11 5.762164e-09 2 28411930 28417317 5388 + 2.748 2.778 0.102

Help

Please Click HERE to learn more details about the results from DEXseq.