ENSG00000076513

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261739 ENSG00000076513 No_inf pgKDN_inf ANKRD13A protein_coding protein_coding 19.1397 24.20462 13.942 1.32573 0.7450368 -0.7954063 6.6766786 5.174315 9.2831165 0.901856 1.7256450 0.8420091 0.39245000 0.211475 0.676075 0.464600 2.415813e-02 1.180496e-09 FALSE TRUE
ENST00000547639 ENSG00000076513 No_inf pgKDN_inf ANKRD13A protein_coding protein_coding 19.1397 24.20462 13.942 1.32573 0.7450368 -0.7954063 2.8025328 3.918910 0.0000000 1.593931 0.0000000 -8.6179855 0.12378333 0.152475 0.000000 -0.152475 5.423736e-02 1.180496e-09 FALSE TRUE
ENST00000551491 ENSG00000076513 No_inf pgKDN_inf ANKRD13A protein_coding protein_coding 19.1397 24.20462 13.942 1.32573 0.7450368 -0.7954063 0.9863116 0.000000 0.1736679 0.000000 0.1736679 4.1990273 0.05445833 0.000000 0.011550 0.011550 7.307699e-01 1.180496e-09 FALSE TRUE
ENST00000553246 ENSG00000076513 No_inf pgKDN_inf ANKRD13A protein_coding retained_intron 19.1397 24.20462 13.942 1.32573 0.7450368 -0.7954063 3.4344258 8.066992 0.0000000 1.185731 0.0000000 -9.6576743 0.14345833 0.330800 0.000000 -0.330800 1.180496e-09 1.180496e-09 FALSE FALSE
MSTRG.7161.4 ENSG00000076513 No_inf pgKDN_inf ANKRD13A protein_coding   19.1397 24.20462 13.942 1.32573 0.7450368 -0.7954063 1.4617357 1.861795 1.1432473 1.149532 1.1432473 -0.6987201 0.08320000 0.082700 0.076050 -0.006650 8.530047e-01 1.180496e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000076513 E001 0.1176306 0.0116448301 4.015157e-01   12 109999186 109999319 134 + 0.108 0.000 -10.160
ENSG00000076513 E002 3.8071604 0.0124476190 8.150109e-01 9.323955e-01 12 109999430 109999683 254 + 0.695 0.663 -0.133
ENSG00000076513 E003 3.5290892 0.0076087083 9.655131e-02 3.235509e-01 12 109999684 109999784 101 + 0.764 0.550 -0.916
ENSG00000076513 E004 7.4729963 0.0020269204 3.242629e-01 6.166924e-01 12 110012005 110012137 133 + 0.976 0.879 -0.366
ENSG00000076513 E005 9.0543976 0.0017143618 1.432972e-01 4.031185e-01 12 110013125 110013249 125 + 1.069 0.936 -0.491
ENSG00000076513 E006 4.7405167 0.0043762286 4.665889e-02 2.119515e-01 12 110016388 110016433 46 + 0.875 0.643 -0.937
ENSG00000076513 E007 3.8841075 0.0038727767 2.711666e-02 1.530725e-01 12 110018345 110018383 39 + 0.823 0.550 -1.150
ENSG00000076513 E008 9.4392296 0.0015238086 3.618376e-01 6.512280e-01 12 110018384 110018488 105 + 1.059 0.977 -0.301
ENSG00000076513 E009 19.0399926 0.0098727351 6.178854e-01 8.345971e-01 12 110019139 110019328 190 + 1.317 1.279 -0.133
ENSG00000076513 E010 1.2590303 0.0098315102 2.333848e-02 1.395488e-01 12 110021108 110021301 194 + 0.108 0.464 2.757
ENSG00000076513 E011 3.6008808 0.0333732381 2.350457e-01 5.241877e-01 12 110021302 110022464 1163 + 0.549 0.720 0.739
ENSG00000076513 E012 0.9984917 0.0127282319 2.973967e-01 5.905157e-01 12 110023619 110024045 427 + 0.194 0.357 1.172
ENSG00000076513 E013 11.8040427 0.0012992518 8.636951e-01 9.528704e-01 12 110024046 110024112 67 + 1.109 1.095 -0.050
ENSG00000076513 E014 6.1742351 0.0024421999 4.859465e-01 7.497723e-01 12 110025742 110025823 82 + 0.804 0.879 0.293
ENSG00000076513 E015 0.0000000       12 110027705 110027707 3 +      
ENSG00000076513 E016 0.0000000       12 110027708 110027766 59 +      
ENSG00000076513 E017 0.0000000       12 110027899 110028511 613 +      
ENSG00000076513 E018 0.0000000       12 110028512 110028557 46 +      
ENSG00000076513 E019 6.3824589 0.0022777113 6.364659e-01 8.448856e-01 12 110028558 110028642 85 + 0.891 0.841 -0.191
ENSG00000076513 E020 0.4996088 0.0157721929 4.763540e-01   12 110028947 110029477 531 + 0.108 0.214 1.172
ENSG00000076513 E021 11.5121230 0.0013634853 2.371787e-01 5.261381e-01 12 110029478 110029550 73 + 1.146 1.049 -0.352
ENSG00000076513 E022 9.1648812 0.0015726628 1.134402e-01 3.543658e-01 12 110029551 110029635 85 + 1.080 0.936 -0.529
ENSG00000076513 E023 11.2054478 0.0056812771 6.582050e-03 6.036325e-02 12 110030645 110030758 114 + 1.203 0.967 -0.856
ENSG00000076513 E024 12.4221483 0.0011654157 2.305700e-03 2.837693e-02 12 110033797 110033931 135 + 1.247 1.005 -0.869
ENSG00000076513 E025 4.4308966 0.0307545630 8.568937e-01 9.497888e-01 12 110033932 110033957 26 + 0.742 0.720 -0.091
ENSG00000076513 E026 0.3802150 0.0203710830 1.726114e-01   12 110036215 110036260 46 + 0.000 0.214 12.295
ENSG00000076513 E027 3.8215121 0.0037977483 9.164201e-01 9.737077e-01 12 110036261 110036270 10 + 0.669 0.683 0.056
ENSG00000076513 E028 8.3049234 0.0049996892 6.249191e-02 2.511676e-01 12 110036271 110036328 58 + 1.059 0.879 -0.668
ENSG00000076513 E029 0.1268540 0.0122657955 7.170942e-01   12 110036329 110036329 1 + 0.000 0.084 10.821
ENSG00000076513 E030 13.5967577 0.0068050765 1.826248e-01 4.591072e-01 12 110037359 110037525 167 + 1.218 1.110 -0.387
ENSG00000076513 E031 186.0021236 0.0001673591 8.163236e-10 7.124207e-08 12 110037526 110039763 2238 + 2.204 2.303 0.330

Help

Please Click HERE to learn more details about the results from DEXseq.