ENSG00000076641

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000220597 ENSG00000076641 No_inf pgKDN_inf PAG1 protein_coding protein_coding 22.89261 25.22512 20.64588 0.3753211 0.08409243 -0.2888805 7.895416 6.483787 8.122921 0.6927417 0.4488710 0.3247135 0.3496333 0.25735 0.393375 0.136025 4.251968e-01 7.091029e-06 FALSE TRUE
MSTRG.27834.1 ENSG00000076641 No_inf pgKDN_inf PAG1 protein_coding   22.89261 25.22512 20.64588 0.3753211 0.08409243 -0.2888805 4.303408 8.745307 0.000000 3.4259975 0.0000000 -9.7740140 0.1769167 0.34405 0.000000 -0.344050 7.091029e-06 7.091029e-06 FALSE TRUE
MSTRG.27834.4 ENSG00000076641 No_inf pgKDN_inf PAG1 protein_coding   22.89261 25.22512 20.64588 0.3753211 0.08409243 -0.2888805 9.623604 9.823818 12.479187 3.7229569 0.4255175 0.3448559 0.4279583 0.39190 0.604475 0.212575 7.629972e-01 7.091029e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000076641 E001 1.4902023 8.875305e-02 5.518672e-01 7.955483e-01 8 80967810 80967851 42 - 0.330 0.429 0.569
ENSG00000076641 E002 314.9744984 8.761124e-05 3.315957e-12 4.037085e-10 8 80967852 80970290 2439 - 2.424 2.534 0.365
ENSG00000076641 E003 59.0996524 2.593600e-04 9.572674e-03 7.815296e-02 8 80970291 80970907 617 - 1.708 1.811 0.348
ENSG00000076641 E004 646.9063603 4.750341e-05 9.274047e-01 9.783938e-01 8 80970908 80975521 4614 - 2.805 2.804 -0.003
ENSG00000076641 E005 148.0487754 1.364059e-04 2.272073e-03 2.812068e-02 8 80975522 80976906 1385 - 2.208 2.135 -0.244
ENSG00000076641 E006 13.7142400 1.234023e-03 1.189234e-01 3.644741e-01 8 80980435 80980494 60 - 1.228 1.107 -0.431
ENSG00000076641 E007 42.5839638 3.568737e-04 1.758574e-06 7.618227e-05 8 80984776 80985227 452 - 1.747 1.530 -0.738
ENSG00000076641 E008 14.5707040 1.221925e-03 7.312676e-05 1.823402e-03 8 80985228 80985377 150 - 1.337 1.038 -1.066
ENSG00000076641 E009 13.2946547 1.060081e-02 1.266966e-02 9.365755e-02 8 80987370 80987466 97 - 1.263 1.046 -0.776
ENSG00000076641 E010 0.0000000       8 80987467 80987534 68 -      
ENSG00000076641 E011 8.8062524 6.586372e-03 9.830994e-02 3.270772e-01 8 80991479 80991530 52 - 1.072 0.912 -0.591
ENSG00000076641 E012 15.5043320 3.379550e-02 8.618008e-01 9.521763e-01 8 80993103 80993307 205 - 1.221 1.203 -0.062
ENSG00000076641 E013 0.3809057 1.587008e-02 1.745965e-01   8 80993504 80993675 172 - 0.000 0.213 11.499
ENSG00000076641 E014 0.6353689 1.507495e-02 4.515156e-02 2.077939e-01 8 80994939 80994986 48 - 0.000 0.313 12.232
ENSG00000076641 E015 0.1272623 1.236668e-02 7.245072e-01   8 81029791 81029995 205 - 0.000 0.083 9.986
ENSG00000076641 E016 7.9784575 2.049635e-03 3.541072e-05 9.931575e-04 8 81029996 81030089 94 - 1.139 0.735 -1.530
ENSG00000076641 E017 0.2448930 1.631744e-02 8.168479e-01   8 81065260 81065294 35 - 0.109 0.083 -0.431
ENSG00000076641 E018 5.1934391 2.752880e-03 3.804809e-04 7.022880e-03 8 81070112 81070170 59 - 0.979 0.573 -1.637
ENSG00000076641 E019 0.0000000       8 81070171 81070176 6 -      
ENSG00000076641 E020 13.2351993 1.550244e-03 1.817286e-01 4.577354e-01 8 81111591 81112068 478 - 1.206 1.100 -0.377

Help

Please Click HERE to learn more details about the results from DEXseq.