ENSG00000077044

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264057 ENSG00000077044 No_inf pgKDN_inf DGKD protein_coding protein_coding 25.13187 35.36886 18.75262 3.201797 0.7173352 -0.9150262 8.8521555 7.184617 8.7930577 0.6138976 2.3535109 0.2910869 0.38732500 0.206000 0.458525 0.252525 3.128638e-01 6.275368e-08 FALSE TRUE
ENST00000409813 ENSG00000077044 No_inf pgKDN_inf DGKD protein_coding protein_coding 25.13187 35.36886 18.75262 3.201797 0.7173352 -0.9150262 0.4551696 0.000000 1.3655089 0.0000000 1.3655089 7.1038216 0.02588333 0.000000 0.077650 0.077650 8.119511e-01 6.275368e-08 FALSE TRUE
ENST00000430834 ENSG00000077044 No_inf pgKDN_inf DGKD protein_coding nonsense_mediated_decay 25.13187 35.36886 18.75262 3.201797 0.7173352 -0.9150262 7.6453971 12.491882 5.7405781 0.9737827 1.4415384 -1.1203663 0.29939167 0.360925 0.315350 -0.045575 8.605800e-01 6.275368e-08 FALSE TRUE
ENST00000471764 ENSG00000077044 No_inf pgKDN_inf DGKD protein_coding retained_intron 25.13187 35.36886 18.75262 3.201797 0.7173352 -0.9150262 2.8315870 8.494761 0.0000000 2.7441900 0.0000000 -9.7321269 0.07592500 0.227775 0.000000 -0.227775 6.275368e-08 6.275368e-08   FALSE
ENST00000495901 ENSG00000077044 No_inf pgKDN_inf DGKD protein_coding retained_intron 25.13187 35.36886 18.75262 3.201797 0.7173352 -0.9150262 2.1904116 3.506940 0.7196601 0.9607704 0.7196601 -2.2690243 0.08254167 0.098550 0.037975 -0.060575 2.955271e-01 6.275368e-08   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000077044 E001 0.3516386 0.0283001219 0.0564737720   2 233354494 233354507 14 + 0.268 0.000 -11.062
ENSG00000077044 E002 1.4487839 0.0125148180 0.0928389341 0.31648916 2 233354508 233354571 64 + 0.515 0.266 -1.428
ENSG00000077044 E003 3.7757248 0.0692717644 0.2806589739 0.57393171 2 233354572 233354674 103 + 0.765 0.597 -0.707
ENSG00000077044 E004 0.0000000       2 233385945 233386010 66 +      
ENSG00000077044 E005 0.0000000       2 233386054 233386214 161 +      
ENSG00000077044 E006 0.0000000       2 233388154 233388256 103 +      
ENSG00000077044 E007 5.1611715 0.0040644436 0.6871301895 0.87092686 2 233388257 233388367 111 + 0.806 0.767 -0.153
ENSG00000077044 E008 0.0000000       2 233388368 233388985 618 +      
ENSG00000077044 E009 5.2299831 0.0027583497 0.0369073937 0.18496222 2 233390403 233390483 81 + 0.908 0.681 -0.902
ENSG00000077044 E010 1.2326882 0.0105379177 0.8943256529 0.96502983 2 233392070 233392399 330 + 0.330 0.355 0.157
ENSG00000077044 E011 0.0000000       2 233408891 233409051 161 +      
ENSG00000077044 E012 0.4907934 0.1229401590 0.7632231476   2 233419241 233419421 181 + 0.195 0.153 -0.428
ENSG00000077044 E013 6.9713402 0.0021043087 0.1883317453 0.46665551 2 233434380 233434466 87 + 0.965 0.839 -0.479
ENSG00000077044 E014 4.3108928 0.0033054021 0.9304728102 0.97968176 2 233434467 233434484 18 + 0.721 0.718 -0.013
ENSG00000077044 E015 8.9615698 0.0015522086 0.4453516479 0.71976213 2 233434769 233434901 133 + 1.028 0.965 -0.230
ENSG00000077044 E016 8.5612442 0.0093573546 0.1420142367 0.40093152 2 233435818 233435924 107 + 1.050 0.912 -0.511
ENSG00000077044 E017 9.7009332 0.0548110418 0.6454694431 0.84992063 2 233436316 233436441 126 + 1.050 1.003 -0.171
ENSG00000077044 E018 7.8298404 0.0117934713 0.2410089872 0.53035104 2 233437377 233437479 103 + 1.004 0.889 -0.428
ENSG00000077044 E019 5.9402425 0.0023923323 0.0032318071 0.03650352 2 233438217 233438312 96 + 0.991 0.681 -1.213
ENSG00000077044 E020 5.0570246 0.0030843915 0.9313093345 0.97999201 2 233438313 233438379 67 + 0.765 0.783 0.069
ENSG00000077044 E021 9.4347841 0.0021098476 0.2078891724 0.49158860 2 233441887 233441995 109 + 1.072 0.965 -0.391
ENSG00000077044 E022 1.3868891 0.0097819640 0.0159824966 0.10964795 2 233441996 233442591 596 + 0.109 0.493 2.893
ENSG00000077044 E023 11.1417500 0.0106798666 0.1434654805 0.40336064 2 233445623 233445762 140 + 1.148 1.021 -0.460
ENSG00000077044 E024 8.8611132 0.0017048119 0.8733967079 0.95685438 2 233446712 233446796 85 + 0.991 0.985 -0.025
ENSG00000077044 E025 2.4842521 0.1186783093 0.3651622951 0.65365626 2 233447701 233447905 205 + 0.432 0.597 0.794
ENSG00000077044 E026 0.8897676 0.0162507490 0.0138690977 0.09938555 2 233448030 233448086 57 + 0.000 0.394 13.309
ENSG00000077044 E027 10.1539239 0.0036832547 0.1321913106 0.38590561 2 233448087 233448181 95 + 1.111 0.985 -0.463
ENSG00000077044 E028 12.9316307 0.0011108193 0.0095329668 0.07797761 2 233448276 233448375 100 + 1.242 1.046 -0.701
ENSG00000077044 E029 26.6873102 0.0072731915 0.0233235183 0.13949109 2 233449103 233449376 274 + 1.512 1.372 -0.482
ENSG00000077044 E030 14.5241693 0.0010377636 0.0063562068 0.05888280 2 233449982 233450131 150 + 1.289 1.093 -0.696
ENSG00000077044 E031 11.5400195 0.0020628500 0.3673445969 0.65597336 2 233450922 233451050 129 + 1.130 1.063 -0.244
ENSG00000077044 E032 10.6149168 0.0045733310 0.6334584123 0.84322497 2 233451964 233452060 97 + 1.028 1.078 0.185
ENSG00000077044 E033 0.4978456 0.0242839552 0.4979880898   2 233454357 233454464 108 + 0.109 0.213 1.157
ENSG00000077044 E034 13.1984079 0.0230828677 0.8532512060 0.94821879 2 233454763 233454873 111 + 1.130 1.155 0.089
ENSG00000077044 E035 11.7314779 0.0259188374 0.6641142342 0.86032258 2 233456899 233456995 97 + 1.061 1.122 0.220
ENSG00000077044 E036 11.2050422 0.0011960357 0.8878622968 0.96249596 2 233457221 233457328 108 + 1.082 1.078 -0.013
ENSG00000077044 E037 6.1476775 0.0096191996 0.0002031732 0.00424474 2 233457329 233457817 489 + 0.515 0.985 1.929
ENSG00000077044 E038 1.1324619 0.0123598675 0.0438177058 0.20443461 2 233458239 233458283 45 + 0.109 0.429 2.572
ENSG00000077044 E039 11.4435727 0.0012814196 0.7044397020 0.87986437 2 233458284 233458397 114 + 1.102 1.078 -0.086
ENSG00000077044 E040 18.8654844 0.0008048802 0.6901021090 0.87274526 2 233459757 233459891 135 + 1.270 1.305 0.125
ENSG00000077044 E041 20.6100260 0.0007607457 0.1504086263 0.41297861 2 233460194 233460345 152 + 1.375 1.292 -0.291
ENSG00000077044 E042 17.4528424 0.0008584297 0.5897685146 0.81834862 2 233462348 233462459 112 + 1.276 1.247 -0.102
ENSG00000077044 E043 16.2990327 0.0008205854 0.4158930208 0.69593789 2 233462643 233462735 93 + 1.190 1.257 0.239
ENSG00000077044 E044 3.8956693 0.1718618487 0.0114107322 0.08775509 2 233463814 233464163 350 + 0.329 0.826 2.328
ENSG00000077044 E045 18.6998332 0.0050981437 0.1019086450 0.33345513 2 233464164 233464283 120 + 1.205 1.336 0.458
ENSG00000077044 E046 21.3290487 0.0006686588 0.7712025286 0.91183000 2 233467086 233467203 118 + 1.326 1.353 0.094
ENSG00000077044 E047 21.5451206 0.0007208427 0.9654698971 0.99276760 2 233468423 233468553 131 + 1.343 1.349 0.020
ENSG00000077044 E048 321.6507433 0.0014132787 0.0006595595 0.01082882 2 233469371 233472104 2734 + 2.463 2.526 0.208

Help

Please Click HERE to learn more details about the results from DEXseq.