ENSG00000077147

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000371142 ENSG00000077147 No_inf pgKDN_inf TM9SF3 protein_coding protein_coding 62.48697 32.67021 80.69386 2.252413 1.483085 1.304221 35.747511 24.949550 43.06325 0.5777279 0.3161424 0.7872002 0.61710833 0.778775 0.534350 -0.244425 0.36261204 0.02654876 FALSE TRUE
ENST00000443638 ENSG00000077147 No_inf pgKDN_inf TM9SF3 protein_coding protein_coding 62.48697 32.67021 80.69386 2.252413 1.483085 1.304221 4.711498 0.000000 10.49757 0.0000000 3.9229374 10.0372139 0.06094167 0.000000 0.130625 0.130625 0.02654876 0.02654876 FALSE FALSE
ENST00000485093 ENSG00000077147 No_inf pgKDN_inf TM9SF3 protein_coding protein_coding_CDS_not_defined 62.48697 32.67021 80.69386 2.252413 1.483085 1.304221 21.747801 7.461149 26.69339 2.5267822 4.2838414 1.8376212 0.31710833 0.213825 0.329450 0.115625 0.77117924 0.02654876 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000077147 E001 0.3522653 0.0296373603 2.413808e-01   10 96518110 96518120 11 - 0.197 0.000 -10.648
ENSG00000077147 E002 626.0336273 0.0000597078 1.689719e-23 6.157657e-21 10 96518121 96522276 4156 - 2.750 2.840 0.301
ENSG00000077147 E003 52.4225179 0.0003536385 3.530597e-01 6.428737e-01 10 96522277 96522330 54 - 1.703 1.740 0.126
ENSG00000077147 E004 53.2803569 0.0043342773 4.064671e-01 6.891374e-01 10 96527213 96527289 77 - 1.710 1.748 0.128
ENSG00000077147 E005 58.5583548 0.0002599223 3.838601e-02 1.891942e-01 10 96527413 96527496 84 - 1.798 1.712 -0.289
ENSG00000077147 E006 0.9647857 0.0129831865 4.415822e-01 7.170344e-01 10 96527497 96527545 49 - 0.333 0.211 -0.883
ENSG00000077147 E007 82.9776309 0.0001820656 8.791861e-03 7.373498e-02 10 96528031 96528177 147 - 1.949 1.858 -0.304
ENSG00000077147 E008 49.8452746 0.0002802861 6.787581e-01 8.670805e-01 10 96530540 96530608 69 - 1.705 1.685 -0.067
ENSG00000077147 E009 54.5304762 0.0003292032 7.300600e-01 8.925548e-01 10 96533051 96533190 140 - 1.731 1.743 0.042
ENSG00000077147 E010 0.7427725 0.0140242023 1.594893e-01 4.268719e-01 10 96543601 96544075 475 - 0.141 0.352 1.702
ENSG00000077147 E011 54.2519533 0.0003591009 1.836687e-01 4.605295e-01 10 96544076 96544206 131 - 1.712 1.764 0.179
ENSG00000077147 E012 40.4395918 0.0005314310 1.820034e-01 4.579766e-01 10 96547895 96547989 95 - 1.634 1.567 -0.227
ENSG00000077147 E013 32.0823067 0.0004328520 2.035107e-03 2.587044e-02 10 96551245 96551310 66 - 1.571 1.399 -0.593
ENSG00000077147 E014 40.7864154 0.0003437062 2.662172e-03 3.152867e-02 10 96551311 96551411 101 - 1.665 1.516 -0.508
ENSG00000077147 E015 40.5142798 0.0086389712 9.702815e-03 7.880283e-02 10 96552928 96553023 96 - 1.667 1.504 -0.557
ENSG00000077147 E016 21.3894709 0.0076955108 1.215608e-01 3.691171e-01 10 96553024 96553059 36 - 1.384 1.267 -0.410
ENSG00000077147 E017 33.5043170 0.0082419124 6.245115e-03 5.810316e-02 10 96559659 96559736 78 - 1.593 1.409 -0.631
ENSG00000077147 E018 51.2372908 0.0032868175 1.968730e-02 1.257032e-01 10 96561978 96562138 161 - 1.752 1.635 -0.396
ENSG00000077147 E019 36.6788141 0.0003938226 3.353332e-03 3.756150e-02 10 96565304 96565426 123 - 1.622 1.469 -0.525
ENSG00000077147 E020 0.0000000       10 96576345 96576633 289 -      
ENSG00000077147 E021 38.1332561 0.0003814614 5.031786e-06 1.894312e-04 10 96576634 96576829 196 - 1.664 1.425 -0.817
ENSG00000077147 E022 0.0000000       10 96577479 96577542 64 -      
ENSG00000077147 E023 0.2455571 0.0163889127 7.025281e-01   10 96586155 96586733 579 - 0.076 0.118 0.702
ENSG00000077147 E024 21.4006911 0.0006341662 1.857211e-04 3.934281e-03 10 96586734 96587012 279 - 1.427 1.168 -0.904
ENSG00000077147 E025 0.1176306 0.0117288848 9.479305e-01   10 96587376 96587452 77 - 0.076 0.000 -11.298

Help

Please Click HERE to learn more details about the results from DEXseq.