ENSG00000077150

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000189444 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding protein_coding 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 10.472822 1.178410 13.60928206 1.1784103 4.65621615 3.5185458 0.12492500 0.033875 0.188125 0.154250 4.137883e-01 4.924951e-07 FALSE  
ENST00000473400 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding retained_intron 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 1.609123 3.245012 0.00000000 0.6761311 0.00000000 -8.3465190 0.03703333 0.097675 0.000000 -0.097675 4.924951e-07 4.924951e-07    
ENST00000651907 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding protein_coding_CDS_not_defined 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 14.055552 7.217537 14.07047559 4.2462154 6.43317139 0.9621200 0.17903333 0.176400 0.174275 -0.002125 8.792736e-01 4.924951e-07    
ENST00000652277 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding protein_coding 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 4.934833 2.835365 4.26239739 1.3993317 1.19289524 0.5864320 0.06982500 0.084275 0.056300 -0.027975 1.000000e+00 4.924951e-07 FALSE  
ENST00000661543 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding protein_coding 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 9.461384 2.532796 12.00386587 1.4671269 5.37433588 2.2402130 0.11740000 0.075025 0.152175 0.077150 5.978175e-01 4.924951e-07 FALSE  
ENST00000697882 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding retained_intron 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 3.692644 1.751349 3.93192968 0.3799565 1.10814947 1.1622213 0.05102500 0.049725 0.054825 0.005100 1.000000e+00 4.924951e-07 FALSE  
ENST00000697883 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding retained_intron 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 3.560811 3.512328 2.92254313 0.6548962 0.44461615 -0.2643770 0.05935000 0.099625 0.039875 -0.059750 3.300404e-01 4.924951e-07 FALSE  
ENST00000697884 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding retained_intron 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 12.852096 4.534910 13.73204269 1.6468799 0.97781743 1.5962730 0.16045833 0.115825 0.184275 0.068450 7.470696e-01 4.924951e-07 FALSE  
ENST00000697918 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding retained_intron 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 2.267987 1.677859 0.09797581 0.6184770 0.09797581 -3.9664142 0.03203333 0.052100 0.001450 -0.050650 9.213978e-02 4.924951e-07    
ENST00000697920 ENSG00000077150 No_inf pgKDN_inf NFKB2 protein_coding protein_coding_CDS_not_defined 74.41324 35.8649 75.69877 3.336143 4.557273 1.077486 5.161807 2.906878 4.00672999 1.8232104 1.78584261 0.4615964 0.07271667 0.091675 0.055200 -0.036475 9.609187e-01 4.924951e-07 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000077150 E001 0.2539903 0.0160364461 5.283080e-02   10 102394110 102394502 393 + 0.000 0.250 12.215
ENSG00000077150 E002 0.7439398 0.0285626195 5.556165e-02 0.2348113337 10 102394503 102394555 53 + 0.116 0.408 2.340
ENSG00000077150 E003 1.9516061 0.1001224061 2.605645e-01 0.5531153080 10 102394556 102394600 45 + 0.377 0.571 0.978
ENSG00000077150 E004 0.4913316 0.0161322880 3.591155e-01   10 102394601 102394774 174 + 0.116 0.250 1.340
ENSG00000077150 E005 0.1268540 0.0123182034 1.891132e-01   10 102395693 102395704 12 + 0.000 0.143 13.889
ENSG00000077150 E006 0.1268540 0.0123182034 1.891132e-01   10 102395705 102395705 1 + 0.000 0.143 13.889
ENSG00000077150 E007 0.1268540 0.0123182034 1.891132e-01   10 102395706 102395706 1 + 0.000 0.143 13.889
ENSG00000077150 E008 3.6127489 0.0455953042 8.831059e-01 0.9606058217 10 102395707 102395796 90 + 0.642 0.614 -0.119
ENSG00000077150 E009 1.9407786 0.0074399517 4.272018e-01 0.7056875782 10 102395797 102395887 91 + 0.405 0.523 0.603
ENSG00000077150 E010 11.1240158 0.0375552004 5.954244e-01 0.8220718390 10 102395888 102395961 74 + 1.029 1.090 0.221
ENSG00000077150 E011 8.3998573 0.0507484074 3.773352e-01 0.6643119837 10 102395962 102395980 19 + 0.969 0.859 -0.414
ENSG00000077150 E012 0.1186381 0.0118317160 1.000000e+00   10 102395981 102396236 256 + 0.062 0.000 -11.735
ENSG00000077150 E013 0.2346346 0.0155928737 8.198957e-01   10 102396237 102396252 16 + 0.116 0.000 -12.709
ENSG00000077150 E014 14.0111692 0.0009958978 5.633575e-02 0.2366733219 10 102396253 102396334 82 + 1.185 1.015 -0.614
ENSG00000077150 E015 10.9195250 0.0012866385 2.683642e-01 0.5618770286 10 102396449 102396489 41 + 1.071 0.963 -0.397
ENSG00000077150 E016 0.7541331 0.1629454421 1.326427e-02 0.0965315503 10 102396490 102396724 235 + 0.062 0.470 3.662
ENSG00000077150 E017 15.7482570 0.0009083828 4.371490e-01 0.7135284247 10 102396725 102396823 99 + 1.206 1.142 -0.230
ENSG00000077150 E018 24.7318313 0.0005683208 1.078497e-01 0.3443019523 10 102396904 102397055 152 + 1.403 1.294 -0.378
ENSG00000077150 E019 14.1902116 0.0025640970 6.424354e-01 0.8483199175 10 102397302 102397341 40 + 1.158 1.116 -0.148
ENSG00000077150 E020 13.5498259 0.0044923928 1.549369e-01 0.4205510467 10 102397342 102397373 32 + 1.162 1.031 -0.475
ENSG00000077150 E021 12.9123773 0.0020921530 7.039422e-01 0.8796085628 10 102397374 102397408 35 + 1.098 1.129 0.112
ENSG00000077150 E022 13.3968310 0.0010255130 7.258224e-01 0.8901198120 10 102397527 102397553 27 + 1.114 1.142 0.099
ENSG00000077150 E023 20.8831942 0.0062842125 7.398201e-01 0.8968699089 10 102397554 102397625 72 + 1.296 1.319 0.082
ENSG00000077150 E024 18.2652217 0.0008522251 2.055622e-01 0.4889003118 10 102397626 102397685 60 + 1.275 1.177 -0.348
ENSG00000077150 E025 24.1618042 0.0219184471 3.278796e-02 0.1716879275 10 102397981 102398072 92 + 1.416 1.209 -0.722
ENSG00000077150 E026 16.0204969 0.0428054087 1.162576e-01 0.3594800151 10 102398073 102398085 13 + 1.245 1.046 -0.713
ENSG00000077150 E027 27.0575480 0.0116129056 2.501074e-02 0.1454803075 10 102398212 102398297 86 + 1.458 1.277 -0.627
ENSG00000077150 E028 0.2447669 0.0163413614 4.649374e-01   10 102398298 102398384 87 + 0.062 0.143 1.340
ENSG00000077150 E029 29.7091451 0.0083789663 3.959787e-01 0.6808614707 10 102398385 102398523 139 + 1.467 1.407 -0.206
ENSG00000077150 E030 3.3951564 0.0247425690 4.170358e-01 0.6967476893 10 102398524 102398738 215 + 0.576 0.690 0.492
ENSG00000077150 E031 10.1526771 0.0324394876 6.694128e-01 0.8625172148 10 102398739 102398751 13 + 0.997 1.046 0.182
ENSG00000077150 E032 19.0372520 0.0012452472 9.170024e-01 0.9739400209 10 102398752 102398864 113 + 1.268 1.259 -0.033
ENSG00000077150 E033 3.3376403 0.0476010905 1.172306e-03 0.0169056522 10 102398865 102399269 405 + 0.405 0.882 2.106
ENSG00000077150 E034 0.8606542 0.0149579204 1.140318e-01 0.3555844840 10 102399270 102399287 18 + 0.165 0.408 1.756
ENSG00000077150 E035 10.9396779 0.0026489644 7.010577e-01 0.8782395584 10 102399288 102399331 44 + 1.053 1.015 -0.141
ENSG00000077150 E036 27.2901154 0.0015944546 4.622830e-01 0.7327531964 10 102399332 102399497 166 + 1.429 1.380 -0.169
ENSG00000077150 E037 17.2844531 0.0008365262 1.485490e-01 0.4105269562 10 102399577 102399660 84 + 1.257 1.142 -0.410
ENSG00000077150 E038 12.9884224 0.0010727082 4.525137e-01 0.7256795704 10 102399661 102399718 58 + 1.129 1.061 -0.245
ENSG00000077150 E039 3.5482647 0.0040531275 2.401279e-02 0.1418983205 10 102399719 102399926 208 + 0.519 0.810 1.241
ENSG00000077150 E040 4.6942521 0.0039581352 1.028283e-05 0.0003494608 10 102399927 102400079 153 + 0.499 1.015 2.118
ENSG00000077150 E041 11.0421185 0.0012473232 6.053601e-02 0.2469579536 10 102400080 102400101 22 + 0.990 1.154 0.595
ENSG00000077150 E042 21.6533061 0.0006394003 1.198745e-01 0.3659333030 10 102400102 102400194 93 + 1.286 1.387 0.352
ENSG00000077150 E043 38.7816841 0.0003977699 8.150442e-01 0.9323955207 10 102400278 102400491 214 + 1.566 1.552 -0.048
ENSG00000077150 E044 2.4474694 0.0056194562 4.228725e-02 0.2002388573 10 102400578 102400590 13 + 0.405 0.690 1.340
ENSG00000077150 E045 3.8244470 0.0046779066 1.582696e-04 0.0034447583 10 102400591 102400654 64 + 0.454 0.924 2.003
ENSG00000077150 E046 43.8539015 0.0003342833 8.380828e-01 0.9420044160 10 102400655 102400824 170 + 1.618 1.606 -0.040
ENSG00000077150 E047 37.5014339 0.0005934232 6.816429e-01 0.8682780953 10 102400947 102401049 103 + 1.542 1.562 0.067
ENSG00000077150 E048 0.4879983 0.0683220738 3.658066e-01   10 102401050 102401179 130 + 0.116 0.250 1.341
ENSG00000077150 E049 42.1391602 0.0003454952 3.060903e-01 0.5992616756 10 102401180 102401331 152 + 1.582 1.630 0.163
ENSG00000077150 E050 20.3955182 0.0008585339 6.945265e-01 0.8752285361 10 102401449 102401518 70 + 1.286 1.311 0.089
ENSG00000077150 E051 1.9603525 0.0070439569 6.961313e-02 0.2668124767 10 102401621 102401744 124 + 0.348 0.614 1.340
ENSG00000077150 E052 32.8525473 0.0005216300 2.667695e-01 0.5601986959 10 102401745 102401917 173 + 1.474 1.533 0.203
ENSG00000077150 E053 16.4856429 0.0008240005 7.525903e-01 0.9025460345 10 102402048 102402104 57 + 1.214 1.188 -0.094
ENSG00000077150 E054 19.0121338 0.0007849104 7.796624e-01 0.9150412962 10 102402105 102402159 55 + 1.272 1.249 -0.079
ENSG00000077150 E055 4.7317977 0.0029751403 1.714434e-01 0.4439517492 10 102402252 102402254 3 + 0.671 0.835 0.662
ENSG00000077150 E056 16.6529356 0.0008459692 5.657168e-01 0.8044337610 10 102402255 102402335 81 + 1.198 1.240 0.148
ENSG00000077150 E057 15.3369410 0.0020825774 4.230239e-01 0.7022956585 10 102402336 102402524 189 + 1.158 1.220 0.219

Help

Please Click HERE to learn more details about the results from DEXseq.