ENSG00000077235

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000356183 ENSG00000077235 No_inf pgKDN_inf GTF3C1 protein_coding protein_coding 45.41898 30.72047 53.65117 4.351441 5.257439 0.8042088 7.923885 7.202059 6.5319817 1.6176534 0.72601477 -0.1406835 0.19758333 0.264575 0.126725 -0.137850 0.58318431 0.03157661 FALSE  
ENST00000561623 ENSG00000077235 No_inf pgKDN_inf GTF3C1 protein_coding protein_coding 45.41898 30.72047 53.65117 4.351441 5.257439 0.8042088 4.213376 1.764367 7.8288590 1.7643667 0.70366573 2.1433395 0.08193333 0.040950 0.152500 0.111550 0.08709620 0.03157661 FALSE  
ENST00000562609 ENSG00000077235 No_inf pgKDN_inf GTF3C1 protein_coding retained_intron 45.41898 30.72047 53.65117 4.351441 5.257439 0.8042088 1.818955 2.511764 0.8466298 0.2020068 0.05637544 -1.5576897 0.04728333 0.085075 0.015975 -0.069100 0.03157661 0.03157661 TRUE  
ENST00000567806 ENSG00000077235 No_inf pgKDN_inf GTF3C1 protein_coding protein_coding_CDS_not_defined 45.41898 30.72047 53.65117 4.351441 5.257439 0.8042088 2.790886 2.321775 0.8531550 1.4623151 0.49497284 -1.4337368 0.05845000 0.061575 0.015100 -0.046475 0.85128937 0.03157661 TRUE  
ENST00000567843 ENSG00000077235 No_inf pgKDN_inf GTF3C1 protein_coding protein_coding_CDS_not_defined 45.41898 30.72047 53.65117 4.351441 5.257439 0.8042088 6.290027 1.719472 9.2701587 1.7194718 3.47382527 2.4238180 0.12255000 0.056375 0.165775 0.109400 0.32337505 0.03157661 FALSE  
ENST00000569394 ENSG00000077235 No_inf pgKDN_inf GTF3C1 protein_coding retained_intron 45.41898 30.72047 53.65117 4.351441 5.257439 0.8042088 2.702614 3.349293 4.7585476 1.9663226 3.26135896 0.5053921 0.05955000 0.101925 0.076725 -0.025200 0.98689412 0.03157661 FALSE  
ENST00000569653 ENSG00000077235 No_inf pgKDN_inf GTF3C1 protein_coding protein_coding 45.41898 30.72047 53.65117 4.351441 5.257439 0.8042088 8.962937 5.097929 10.8402204 2.5217252 0.29708851 1.0869139 0.18960000 0.151800 0.206625 0.054825 0.81043653 0.03157661 FALSE  
MSTRG.10898.2 ENSG00000077235 No_inf pgKDN_inf GTF3C1 protein_coding   45.41898 30.72047 53.65117 4.351441 5.257439 0.8042088 9.196716 6.031300 10.1901410 0.9000458 1.25401823 0.7556581 0.20814167 0.211700 0.188925 -0.022775 0.98603744 0.03157661 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000077235 E001 0.0000000       16 27459555 27459613 59 -      
ENSG00000077235 E002 0.0000000       16 27460456 27460612 157 -      
ENSG00000077235 E003 6.5206478 0.0103064812 7.941802e-02 2.890707e-01 16 27460613 27460675 63 - 0.778 0.971 0.739
ENSG00000077235 E004 78.0515552 0.0002642718 1.824445e-01 4.588465e-01 16 27460676 27461096 421 - 1.875 1.919 0.150
ENSG00000077235 E005 54.0963332 0.0002905521 2.306079e-03 2.837693e-02 16 27461097 27461295 199 - 1.680 1.802 0.414
ENSG00000077235 E006 56.0033153 0.0002680625 9.946843e-01 1.000000e+00 16 27461296 27461562 267 - 1.753 1.752 -0.002
ENSG00000077235 E007 0.8617267 0.0125195220 4.248657e-01 7.039994e-01 16 27461563 27462293 731 - 0.211 0.333 0.882
ENSG00000077235 E008 46.5434098 0.0072245596 3.114404e-01 6.046051e-01 16 27462294 27462486 193 - 1.697 1.642 -0.185
ENSG00000077235 E009 1.8037282 0.0074859132 2.229062e-01 5.103283e-01 16 27462487 27463473 987 - 0.517 0.333 -0.993
ENSG00000077235 E010 19.2504658 0.0056343159 6.907317e-01 8.730183e-01 16 27463541 27463592 52 - 1.291 1.319 0.100
ENSG00000077235 E011 11.8663915 0.0012442650 6.924403e-12 8.056805e-10 16 27463593 27464319 727 - 0.747 1.342 2.197
ENSG00000077235 E012 8.2159948 0.0018152833 9.477733e-02 3.202722e-01 16 27464320 27464394 75 - 0.884 1.044 0.596
ENSG00000077235 E013 8.4808602 0.0016466977 3.037481e-02 1.640006e-01 16 27464395 27464409 15 - 0.872 1.077 0.760
ENSG00000077235 E014 67.8024734 0.0005522618 9.439446e-01 9.844857e-01 16 27464410 27464836 427 - 1.835 1.833 -0.009
ENSG00000077235 E015 49.9512716 0.0002948799 6.934944e-01 8.747995e-01 16 27465260 27465540 281 - 1.697 1.713 0.056
ENSG00000077235 E016 0.3802764 0.0282782112 5.574981e-02   16 27465541 27466327 787 - 0.000 0.270 12.701
ENSG00000077235 E017 36.9506720 0.0004183856 4.267867e-01 7.053693e-01 16 27469291 27469401 111 - 1.559 1.597 0.132
ENSG00000077235 E018 42.6558445 0.0003898483 5.797115e-01 8.123717e-01 16 27469402 27469550 149 - 1.626 1.651 0.085
ENSG00000077235 E019 13.8793864 0.0072998863 9.803959e-01 9.978172e-01 16 27470108 27470108 1 - 1.169 1.171 0.007
ENSG00000077235 E020 28.9341019 0.0004912187 6.089082e-01 8.297992e-01 16 27470109 27470222 114 - 1.485 1.457 -0.098
ENSG00000077235 E021 33.8035119 0.0010829670 2.988086e-02 1.626070e-01 16 27470223 27470395 173 - 1.585 1.470 -0.396
ENSG00000077235 E022 0.1271363 0.0123479033 3.863338e-01   16 27470683 27470719 37 - 0.000 0.110 11.172
ENSG00000077235 E023 0.0000000       16 27471565 27471747 183 -      
ENSG00000077235 E024 17.4486169 0.0007961889 1.097351e-01 3.476684e-01 16 27471748 27471790 43 - 1.309 1.195 -0.400
ENSG00000077235 E025 27.3225105 0.0007228263 2.545060e-01 5.462642e-01 16 27471791 27471920 130 - 1.476 1.411 -0.226
ENSG00000077235 E026 24.5480562 0.0005588109 4.084134e-01 6.907495e-01 16 27476451 27476544 94 - 1.425 1.375 -0.172
ENSG00000077235 E027 22.0596557 0.0006194601 7.609335e-01 9.065609e-01 16 27478469 27478531 63 - 1.351 1.370 0.065
ENSG00000077235 E028 0.2442663 0.0165233238 8.015042e-01   16 27478532 27478594 63 - 0.082 0.110 0.467
ENSG00000077235 E029 0.5968488 0.0151114511 3.105502e-01 6.036406e-01 16 27480716 27481078 363 - 0.263 0.110 -1.533
ENSG00000077235 E030 18.1585786 0.0018741646 8.119594e-01 9.308014e-01 16 27481079 27481114 36 - 1.272 1.288 0.057
ENSG00000077235 E031 23.1865859 0.0054046045 4.097014e-01 6.918863e-01 16 27481115 27481191 77 - 1.355 1.411 0.192
ENSG00000077235 E032 0.1186381 0.0119063954 7.445523e-01   16 27482511 27482585 75 - 0.082 0.000 -10.576
ENSG00000077235 E033 18.5075818 0.0007836852 9.744556e-01 9.954114e-01 16 27483044 27483125 82 - 1.286 1.288 0.007
ENSG00000077235 E034 0.2533610 0.0160751744 1.499775e-01   16 27483138 27483432 295 - 0.000 0.197 12.152
ENSG00000077235 E035 23.4585121 0.0280769461 5.002193e-01 7.603521e-01 16 27484211 27484353 143 - 1.412 1.348 -0.219
ENSG00000077235 E036 23.2375442 0.0032348305 6.582884e-01 8.571648e-01 16 27485997 27486139 143 - 1.393 1.365 -0.100
ENSG00000077235 E037 11.6826044 0.0099539706 9.599023e-01 9.907448e-01 16 27486140 27486154 15 - 1.102 1.097 -0.019
ENSG00000077235 E038 0.0000000       16 27488219 27488226 8 -      
ENSG00000077235 E039 28.6140134 0.0166219760 8.541751e-01 9.485068e-01 16 27488227 27488415 189 - 1.464 1.474 0.034
ENSG00000077235 E040 13.7707587 0.0012118938 7.664918e-01 9.093869e-01 16 27488554 27488635 82 - 1.156 1.179 0.081
ENSG00000077235 E041 14.8702724 0.0009377981 7.436145e-01 8.986056e-01 16 27489043 27489178 136 - 1.187 1.211 0.086
ENSG00000077235 E042 18.3162354 0.0007997756 2.237697e-01 5.113464e-01 16 27489602 27489743 142 - 1.318 1.233 -0.296
ENSG00000077235 E043 23.1165598 0.0057863481 8.099531e-01 9.298625e-01 16 27492338 27492515 178 - 1.386 1.370 -0.055
ENSG00000077235 E044 17.7083803 0.0008243952 2.219450e-01 5.091829e-01 16 27492617 27492713 97 - 1.304 1.218 -0.302
ENSG00000077235 E045 13.3926679 0.0010444991 9.740973e-01 9.953877e-01 16 27493199 27493296 98 - 1.156 1.153 -0.010
ENSG00000077235 E046 14.4569082 0.0067077973 6.185412e-01 8.349577e-01 16 27494763 27494908 146 - 1.204 1.162 -0.149
ENSG00000077235 E047 20.1699996 0.0039864149 4.930282e-01 7.550252e-01 16 27495211 27495492 282 - 1.343 1.294 -0.169
ENSG00000077235 E048 16.3091548 0.0008319821 9.728944e-03 7.888769e-02 16 27497637 27497821 185 - 1.309 1.117 -0.680
ENSG00000077235 E049 9.5674587 0.0014520620 2.398165e-01 5.288976e-01 16 27498630 27498733 104 - 1.065 0.957 -0.399
ENSG00000077235 E050 11.0633824 0.0027429110 8.016469e-01 9.259836e-01 16 27501191 27501306 116 - 1.088 1.066 -0.079
ENSG00000077235 E051 6.6975135 0.0901041034 8.609213e-01 9.518456e-01 16 27501307 27501344 38 - 0.884 0.882 -0.009
ENSG00000077235 E052 11.4325362 0.0140071277 9.352389e-01 9.813649e-01 16 27502859 27502995 137 - 1.095 1.087 -0.029
ENSG00000077235 E053 13.8046987 0.0015043520 1.379203e-01 3.952283e-01 16 27505899 27506116 218 - 1.215 1.097 -0.421
ENSG00000077235 E054 21.0052919 0.0008242763 3.896634e-01 6.753264e-01 16 27506847 27507156 310 - 1.363 1.307 -0.195
ENSG00000077235 E055 9.6037343 0.0105831141 8.160415e-01 9.327765e-01 16 27508540 27508655 116 - 1.033 1.009 -0.088
ENSG00000077235 E056 12.3045886 0.0021051651 9.030020e-01 9.688647e-01 16 27511749 27511901 153 - 1.117 1.126 0.035
ENSG00000077235 E057 8.7097803 0.0116721237 1.696488e-01 4.417012e-01 16 27528598 27528721 124 - 1.041 0.898 -0.534
ENSG00000077235 E058 7.6737110 0.0017668198 8.880702e-01 9.625639e-01 16 27533291 27533387 97 - 0.929 0.943 0.051
ENSG00000077235 E059 11.0594145 0.0214057377 8.144715e-01 9.322775e-01 16 27537784 27537927 144 - 1.088 1.066 -0.079
ENSG00000077235 E060 12.1093089 0.0133384405 2.133423e-01 4.985876e-01 16 27538180 27538356 177 - 1.162 1.044 -0.427
ENSG00000077235 E061 10.1377980 0.0018082634 3.625495e-01 6.518310e-01 16 27545314 27545523 210 - 1.007 1.087 0.292
ENSG00000077235 E062 8.0351870 0.0017380114 9.410591e-01 9.833969e-01 16 27549670 27549913 244 - 0.950 0.957 0.026

Help

Please Click HERE to learn more details about the results from DEXseq.