ENSG00000077380

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340296 ENSG00000077380 No_inf pgKDN_inf DYNC1I2 protein_coding protein_coding 47.70167 44.69255 55.74187 3.033152 3.05319 0.3186633 15.041111 6.115822 21.340718 2.4012892 3.036154 1.801309 0.31372500 0.133675 0.394000 0.260325 0.08857914 0.02737684 FALSE TRUE
ENST00000409197 ENSG00000077380 No_inf pgKDN_inf DYNC1I2 protein_coding protein_coding 47.70167 44.69255 55.74187 3.033152 3.05319 0.3186633 25.460639 28.712488 24.308121 0.6993481 1.124390 -0.240149 0.54515000 0.650750 0.437300 -0.213450 0.02737684 0.02737684 FALSE TRUE
ENST00000425485 ENSG00000077380 No_inf pgKDN_inf DYNC1I2 protein_coding protein_coding 47.70167 44.69255 55.74187 3.033152 3.05319 0.3186633 1.384536 0.000000 4.153607 0.0000000 4.153607 8.701690 0.02154167 0.000000 0.064625 0.064625 0.85504855 0.02737684 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000077380 E001 0.3622142 0.0166005389 0.6463580917   2 171687409 171687468 60 + 0.166 0.099 -0.859
ENSG00000077380 E002 0.3543453 0.0158385318 0.1233214918   2 171687469 171687470 2 + 0.230 0.000 -14.124
ENSG00000077380 E003 0.3543453 0.0158385318 0.1233214918   2 171687471 171687471 1 + 0.230 0.000 -14.124
ENSG00000077380 E004 2.1700013 0.0977481881 0.1370769126 0.394100430 2 171687472 171687500 29 + 0.605 0.359 -1.238
ENSG00000077380 E005 11.6052340 0.0069549607 0.0083670242 0.071267701 2 171687501 171687627 127 + 1.202 0.965 -0.859
ENSG00000077380 E006 0.1272623 0.0123426810 0.4879799348   2 171687672 171687704 33 + 0.000 0.099 12.716
ENSG00000077380 E007 0.1272623 0.0123426810 0.4879799348   2 171687705 171687707 3 + 0.000 0.099 12.716
ENSG00000077380 E008 0.7498861 0.2766692698 0.1742082868 0.447843172 2 171687708 171687743 36 + 0.091 0.359 2.463
ENSG00000077380 E009 0.9957255 0.0776809604 0.1467667004 0.407816343 2 171687744 171687754 11 + 0.166 0.405 1.726
ENSG00000077380 E010 3.2187878 0.0057110900 0.0711026540 0.270225537 2 171687755 171687775 21 + 0.491 0.730 1.059
ENSG00000077380 E011 5.3055863 0.0029677968 0.0927144274 0.316224621 2 171687776 171687791 16 + 0.696 0.886 0.754
ENSG00000077380 E012 10.9174225 0.0012783264 0.3231107788 0.615851658 2 171687792 171687873 82 + 1.033 1.117 0.303
ENSG00000077380 E013 0.1170040 0.0117637456 0.5930839503   2 171687881 171688003 123 + 0.091 0.000 -12.539
ENSG00000077380 E014 0.0000000       2 171688006 171688010 5 +      
ENSG00000077380 E015 0.2459004 0.0166318278 0.9398686570   2 171688011 171688166 156 + 0.091 0.099 0.141
ENSG00000077380 E016 0.2438580 0.0163910397 0.9391480770   2 171688303 171688309 7 + 0.091 0.099 0.141
ENSG00000077380 E017 0.1170040 0.0117637456 0.5930839503   2 171688310 171688358 49 + 0.091 0.000 -12.539
ENSG00000077380 E018 0.2537694 0.0159405758 0.2108685083   2 171688471 171688648 178 + 0.000 0.180 13.716
ENSG00000077380 E019 0.0000000       2 171690145 171690146 2 +      
ENSG00000077380 E020 39.1487914 0.0003751004 0.2279284026 0.516413246 2 171690147 171690263 117 + 1.631 1.574 -0.193
ENSG00000077380 E021 45.8022799 0.0003630972 0.0479810430 0.215511781 2 171692777 171692894 118 + 1.710 1.625 -0.292
ENSG00000077380 E022 0.4831157 0.0424871191 0.3754213679   2 171692895 171693084 190 + 0.230 0.099 -1.444
ENSG00000077380 E023 0.0000000       2 171706547 171706564 18 +      
ENSG00000077380 E024 0.1272623 0.0123426810 0.4879799348   2 171706890 171707232 343 + 0.000 0.099 12.716
ENSG00000077380 E025 0.1272623 0.0123426810 0.4879799348   2 171707233 171707286 54 + 0.000 0.099 12.716
ENSG00000077380 E026 11.5684453 0.0015585191 0.3948962864 0.679688832 2 171707287 171707377 91 + 1.133 1.062 -0.256
ENSG00000077380 E027 0.0000000       2 171712402 171712766 365 +      
ENSG00000077380 E028 0.1265070 0.0122807961 0.4879966679   2 171712767 171712826 60 + 0.000 0.099 12.716
ENSG00000077380 E029 5.1819354 0.0027731997 0.1236379706 0.372342973 2 171715328 171715389 62 + 0.696 0.871 0.698
ENSG00000077380 E030 17.7349960 0.0007795597 0.8588713829 0.950846094 2 171715390 171715443 54 + 1.267 1.279 0.042
ENSG00000077380 E031 48.8861173 0.0003065957 0.8236829301 0.936001752 2 171725618 171725713 96 + 1.703 1.693 -0.032
ENSG00000077380 E032 57.0183849 0.0033857439 0.6762975070 0.865839113 2 171725919 171726081 163 + 1.754 1.773 0.067
ENSG00000077380 E033 0.8618527 0.0124810688 0.6142853127 0.832371029 2 171726082 171726193 112 + 0.230 0.307 0.556
ENSG00000077380 E034 50.0908109 0.0003327096 0.2867582999 0.580229681 2 171726194 171726293 100 + 1.686 1.730 0.148
ENSG00000077380 E035 0.7370111 0.0571608696 0.9144767872 0.973093890 2 171726558 171726790 233 + 0.230 0.248 0.141
ENSG00000077380 E036 40.9664185 0.0039505379 0.9888241713 1.000000000 2 171726791 171726916 126 + 1.624 1.622 -0.006
ENSG00000077380 E037 57.6452532 0.0046457486 0.5651559749 0.804115775 2 171727821 171727967 147 + 1.781 1.754 -0.092
ENSG00000077380 E038 39.1856375 0.0004679674 0.3160376499 0.608946360 2 171728305 171728418 114 + 1.580 1.627 0.159
ENSG00000077380 E039 33.9420110 0.0005080360 0.6151826152 0.832966831 2 171728717 171728850 134 + 1.556 1.530 -0.088
ENSG00000077380 E040 48.7809003 0.0042179847 0.7689692695 0.910626835 2 171729709 171729853 145 + 1.690 1.704 0.047
ENSG00000077380 E041 28.7910404 0.0005307614 0.2775267699 0.570769934 2 171744049 171744189 141 + 1.444 1.503 0.203
ENSG00000077380 E042 49.5886756 0.0003184860 0.5408353859 0.788686568 2 171745802 171745927 126 + 1.716 1.691 -0.087
ENSG00000077380 E043 25.4094750 0.0005855420 0.0318130753 0.168596483 2 171747776 171747778 3 + 1.479 1.354 -0.432
ENSG00000077380 E044 69.6863180 0.0002285089 0.8634513310 0.952789576 2 171747779 171748766 988 + 1.846 1.852 0.020
ENSG00000077380 E045 2.4864838 0.0069994267 0.0454152355 0.208443989 2 171748767 171748885 119 + 0.380 0.663 1.364
ENSG00000077380 E046 12.3824650 0.0013150500 0.0004887272 0.008580407 2 171748886 171750158 1273 + 0.962 1.248 1.034
ENSG00000077380 E047 0.4985363 0.0152843539 0.2742513940   2 171751954 171751975 22 + 0.091 0.248 1.726

Help

Please Click HERE to learn more details about the results from DEXseq.