ENSG00000077549

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264202 ENSG00000077549 No_inf pgKDN_inf CAPZB protein_coding protein_coding 342.9423 301.9315 358.9553 6.938147 5.621143 0.2495753 175.51310 166.1988 182.60054 2.2364075 1.544873 0.1357731228 0.5145000 0.551050 0.509300 -0.041750 0.55542908 0.02668639 FALSE TRUE
ENST00000489607 ENSG00000077549 No_inf pgKDN_inf CAPZB protein_coding protein_coding_CDS_not_defined 342.9423 301.9315 358.9553 6.938147 5.621143 0.2495753 56.01391 21.1233 66.42679 5.6569111 7.243093 1.6524639869 0.1572583 0.068875 0.184450 0.115575 0.02668639 0.02668639 FALSE FALSE
MSTRG.376.8 ENSG00000077549 No_inf pgKDN_inf CAPZB protein_coding   342.9423 301.9315 358.9553 6.938147 5.621143 0.2495753 99.94065 100.5997 100.65141 0.4281303 4.583419 0.0007418454 0.2940750 0.333650 0.280475 -0.053175 0.37330492 0.02668639 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000077549 E001 0.8545198 2.156209e-01 7.191933e-01 8.868075e-01 1 19338775 19338775 1 - 0.304 0.233 -0.516
ENSG00000077549 E002 75.7892923 2.474013e-04 2.847123e-01 5.784334e-01 1 19338776 19339136 361 - 1.903 1.867 -0.124
ENSG00000077549 E003 144.2884447 1.189517e-04 5.877645e-01 8.170501e-01 1 19339137 19339230 94 - 2.154 2.168 0.047
ENSG00000077549 E004 75.0854618 7.230353e-04 1.463044e-01 4.072825e-01 1 19339231 19339244 14 - 1.851 1.904 0.179
ENSG00000077549 E005 181.1791375 1.352336e-04 5.683063e-02 2.380822e-01 1 19339245 19339324 80 - 2.236 2.279 0.145
ENSG00000077549 E006 147.6053961 1.365385e-04 1.515132e-01 4.149013e-01 1 19339325 19339358 34 - 2.151 2.187 0.121
ENSG00000077549 E007 144.6087303 1.964485e-03 1.049235e-01 3.387168e-01 1 19339359 19339373 15 - 2.135 2.185 0.168
ENSG00000077549 E008 551.5247459 2.067242e-04 1.816410e-02 1.190379e-01 1 19339374 19339617 244 - 2.724 2.756 0.104
ENSG00000077549 E009 50.7611321 3.173772e-04 1.390565e-28 7.352819e-26 1 19339618 19342751 3134 - 1.363 1.883 1.774
ENSG00000077549 E010 4.3575411 3.395645e-02 3.800990e-02 1.880760e-01 1 19342752 19342864 113 - 0.548 0.839 1.221
ENSG00000077549 E011 16.9739183 8.428505e-04 4.372227e-09 3.311962e-07 1 19342865 19344357 1493 - 0.960 1.408 1.600
ENSG00000077549 E012 253.4774344 9.053261e-05 6.730532e-01 8.645797e-01 1 19344358 19344434 77 - 2.409 2.401 -0.025
ENSG00000077549 E013 4.5818192 1.783633e-02 6.873447e-02 2.647379e-01 1 19344435 19345186 752 - 0.606 0.839 0.959
ENSG00000077549 E014 239.2681672 7.562804e-05 6.981260e-01 8.768537e-01 1 19345187 19345252 66 - 2.383 2.376 -0.024
ENSG00000077549 E015 11.7794637 7.213314e-03 4.326652e-03 4.478956e-02 1 19345253 19346362 1110 - 0.947 1.208 0.945
ENSG00000077549 E016 144.6320441 1.325509e-04 7.793615e-01 9.149984e-01 1 19356635 19356654 20 - 2.166 2.159 -0.022
ENSG00000077549 E017 276.5055003 7.988011e-05 9.637639e-02 3.233369e-01 1 19356655 19356746 92 - 2.458 2.428 -0.098
ENSG00000077549 E018 140.4324155 1.315607e-04 2.381509e-02 1.412167e-01 1 19356747 19356751 5 - 2.179 2.122 -0.191
ENSG00000077549 E019 256.5935134 7.467958e-05 1.254637e-01 3.754852e-01 1 19357422 19357521 100 - 2.425 2.397 -0.094
ENSG00000077549 E020 149.5862110 1.149405e-04 3.876351e-01 6.733769e-01 1 19357522 19357563 42 - 2.188 2.167 -0.070
ENSG00000077549 E021 18.8345966 8.060990e-04 2.960790e-04 5.742081e-03 1 19374048 19378539 4492 - 1.144 1.396 0.885
ENSG00000077549 E022 229.8211580 8.147703e-05 2.794474e-01 5.727510e-01 1 19378540 19378653 114 - 2.373 2.352 -0.070
ENSG00000077549 E023 266.1276500 1.676921e-03 3.661391e-02 1.840951e-01 1 19385505 19385626 122 - 2.452 2.402 -0.166
ENSG00000077549 E024 6.6156163 2.113762e-03 9.896045e-01 1.000000e+00 1 19385721 19385827 107 - 0.880 0.882 0.006
ENSG00000077549 E025 1.7070566 7.927806e-03 5.104672e-01 7.680052e-01 1 19412236 19417164 4929 - 0.481 0.384 -0.515
ENSG00000077549 E026 212.0571473 1.054003e-04 1.432751e-05 4.657867e-04 1 19419661 19419750 90 - 2.373 2.284 -0.297
ENSG00000077549 E027 2.5577655 5.420492e-03 4.204313e-01 6.997759e-01 1 19420025 19420144 120 - 0.607 0.495 -0.515
ENSG00000077549 E028 0.5066574 2.007079e-01 8.625922e-02 3.043209e-01 1 19448834 19449330 497 - 0.000 0.289 10.420
ENSG00000077549 E029 4.1571920 3.359281e-03 5.881178e-01 8.171847e-01 1 19484190 19484891 702 - 0.745 0.680 -0.270
ENSG00000077549 E030 135.8845118 1.223363e-04 1.262765e-03 1.790849e-02 1 19485436 19485539 104 - 2.178 2.095 -0.277

Help

Please Click HERE to learn more details about the results from DEXseq.